SR ONE CAPITAL MANAGEMENT, LP Long-Term Concentrated

Location: Redwood City, CA

CIK: 0001910264 · Show all filings

Period: Q4 2024 (← Previous) (Next →)

Filing Date: Feb 13, 2025

Total Value: $410M (100.0% shares, 0.0% debt)

Holdings (11)

ACLX Arcellx, Inc. 43.9%

Value $180M Shares 2,346,630 Est. Cost $16.72 Unrealized +416.7%

SPRY ARS Pharmaceuticals, Inc. 10.3%

Value $42.34M Shares 4,012,903 Est. Cost $6.79 Unrealized +106.4%

CRSP CRISPR Therapeutics AG 10.1%

Value $41.29M Shares 1,048,951 Est. Cost $71.59 Unrealized -34.0%

DSGN Design Therapeutics, Inc. 9.8%

Value $40.27M Shares 6,526,476 Est. Cost $16.67 Unrealized -65.3%

ZBIO Zenas BioPharma, Inc 9.8%

Value $40.23M Shares 4,911,539 Est. Cost $17.98 Unrealized -13.2%

MLYS Mineralys Therapeutics Inc. 6.1%

Value $24.83M Shares 2,016,822 Est. Cost $16.34 Unrealized -20.0%

ALMS Alumis Inc. 3.8%

Value $15.4M Shares 1,959,896 Est. Cost $13.30 Unrealized -24.6%

ORKA Oruka Therapeutics, Inc 2.0%

Value $8.344M Shares 430,330 Est. Cost $33.46 Unrealized -27.1%

NKTX Nkarta, Inc. 2.0%

Value $8.3M Shares 3,333,333 Est. Cost $11.49 Unrealized -73.1%

ENGN enGene Holdings Inc. 1.2%

Value $4.973M Shares 747,750 Est. Cost $11.04 Unrealized -29.7%

KALA KALA Bio, Inc. 1.0%

Value $4.157M Shares 598,940 Est. Cost $6.53 Unrealized -3.4%

Ticker	Issuer	Shares	Value	%	Est. Cost	Unrealized	Class	CUSIP
ACLX	Arcellx, Inc.	2,346,630	$180M	43.9%	$16.72	+416.7%	Common Stock	03940C100
SPRY	ARS Pharmaceuticals, Inc.	4,012,903	$42.34M	10.3%	$6.79	+106.4%	Common Stock	82835W108
CRSP	CRISPR Therapeutics AG	1,048,951	$41.29M	10.1%	$71.59	-34.0%	Common Shares	H17182108
DSGN	Design Therapeutics, Inc.	6,526,476	$40.27M	9.8%	$16.67	-65.3%	Common Stock	25056L103
ZBIO	Zenas BioPharma, Inc	4,911,539	$40.23M	9.8%	$17.98	-13.2%	Common Stock	98937L105
MLYS	Mineralys Therapeutics Inc.	2,016,822	$24.83M	6.1%	$16.34	-20.0%	Common Stock	603170101
ALMS	Alumis Inc.	1,959,896	$15.4M	3.8%	$13.30	-24.6%	Common Stock	022307102
ORKA	Oruka Therapeutics, Inc	430,330	$8.344M	2.0%	$33.46	-27.1%	Common Stock	687604108
NKTX	Nkarta, Inc.	3,333,333	$8.3M	2.0%	$11.49	-73.1%	Common Stock	65487U108
ENGN	enGene Holdings Inc.	747,750	$4.973M	1.2%	$11.04	-29.7%	Common Shares	29286M105
KALA	KALA Bio, Inc.	598,940	$4.157M	1.0%	$6.53	-3.4%	Common Stock	483119202