Pivotal bioVenture Partners Investment Advisor LLC Long-Term Concentrated

Location: SAN FRANCISCO, CA

CIK: 0001844645 · Show all filings

Period: Q1 2026 (← Previous)

Filing Date: May 14, 2026

Total Value ($000): $279,778 (100.0% shares, 0.0% debt)

Holdings (13)

New Positions (2)

AVTX AVALO THERAPEUTICS INC 1.6%

Value ($000) $4,418 Shares 295,933 Est. Cost $15.50 Unrealized 0.0%

RLYB RALLYBIO CORP 1.0%

Value ($000) $2,696 Shares 300,579 Est. Cost $5.22 Unrealized 0.0%

Ticker	Issuer	Shares	Value ($000)	%	Est. Cost	Unrealized	Class	CUSIP
AVTX	AVALO THERAPEUTICS INC	295,933	$4,418	1.6%	$15.50	0.0%	COM NEW	05338F306
RLYB	RALLYBIO CORP	300,579	$2,696	1.0%	$5.22	0.0%	COM	75120L209

Increased Positions (1)

TRVI TREVI THERAPEUTICS INC 6.6%

Value ($000) $18,536 (+17.8%) Shares 1,553,726 (+23.6%) Est. Cost $7.21 Unrealized +51.7%

Ticker	Issuer	Shares	Value ($000)	%	Est. Cost	Unrealized	Class	CUSIP
TRVI	TREVI THERAPEUTICS INC	1,553,726 (+23.6%)	$18,536 (+17.8%)	6.6%	$7.21	+51.7%	COM	89532M101

Exited Positions (1)

— RALLYBIO CORP 0.6%

Value ($000) $1,650 Shares 2,404,644 Est. Cost $16.97 Unrealized —

Ticker	Issuer	Shares	Value ($000)	%	Est. Cost	Unrealized	Class	CUSIP
—	RALLYBIO CORP	2,404,644	$1,650	0.6%	$16.97	—	—	75120L100

Decreased Positions (2)

OCS OCULIS HOLDING AG 16.0%

Value ($000) $44,679 (-2.2%) Shares 1,680,283 (-26.6%) Est. Cost $12.64 Unrealized +109.5%

BOLT BOLT BIOTHERAPEUTICS INC 0.1%

Value ($000) $172 (-66.7%) Shares 42,581 (-55.0%) Est. Cost $6.62 Unrealized -13.4%

Ticker	Issuer	Shares	Value ($000)	%	Est. Cost	Unrealized	Class	CUSIP
OCS	OCULIS HOLDING AG	1,680,283 (-26.6%)	$44,679 (-2.2%)	16.0%	$12.64	+109.5%	ORDINARY SHARES	H5870P102
BOLT	BOLT BIOTHERAPEUTICS INC	42,581 (-55.0%)	$172 (-66.7%)	0.1%	$6.62	-13.4%	COM NEW	097702203

Unchanged Positions (8)

PCVX VAXCYTE INC 28.5%

Value ($000) $79,752 Shares 1,372,425 Est. Cost $38.62 Unrealized +36.6%

EVMN EVOMMUNE INC 15.8%

Value ($000) $44,300 Shares 1,926,943 Est. Cost $18.78 Unrealized +17.1%

ZBIO ZENAS BIOPHARMA INC 4.1%

Value ($000) $11,573 Shares 591,991 Est. Cost $17.27 Unrealized +26.7%

ARQT ARCUTIS BIOTHERAPEUTICS INC 11.4%

Value ($000) $31,945 Shares 1,355,892 Est. Cost $11.27 Unrealized +138.4%

BIOA BIOAGE LABS INC 4.1%

Value ($000) $11,428 Shares 653,374 Est. Cost $19.50 Unrealized -1.5%

MPLT MAPLIGHT THERAPEUTICS INC 4.4%

Value ($000) $12,431 Shares 611,447 Est. Cost $16.75 Unrealized +5.2%

RXRX RECURSION PHARMACEUTICALS IN 0.7%

Value ($000) $1,828 Shares 595,518 Est. Cost $6.72 Unrealized -37.9%

IMNM IMMUNOME INC 5.7%

Value ($000) $16,020 Shares 732,512 Est. Cost $12.33 Unrealized +87.0%

Ticker	Issuer	Shares	Value ($000)	%	Est. Cost	Unrealized	Class	CUSIP
PCVX	VAXCYTE INC	1,372,425	$79,752	28.5%	$38.62	+36.6%	COM	92243G108
EVMN	EVOMMUNE INC	1,926,943	$44,300	15.8%	$18.78	+17.1%	COM SHS	30054Y107
ZBIO	ZENAS BIOPHARMA INC	591,991	$11,573	4.1%	$17.27	+26.7%	COM	98937L105
ARQT	ARCUTIS BIOTHERAPEUTICS INC	1,355,892	$31,945	11.4%	$11.27	+138.4%	COM	03969K108
BIOA	BIOAGE LABS INC	653,374	$11,428	4.1%	$19.50	-1.5%	COM	09077V100
MPLT	MAPLIGHT THERAPEUTICS INC	611,447	$12,431	4.4%	$16.75	+5.2%	COM	56565P103
RXRX	RECURSION PHARMACEUTICALS IN	595,518	$1,828	0.7%	$6.72	-37.9%	CL A	75629V104
IMNM	IMMUNOME INC	732,512	$16,020	5.7%	$12.33	+87.0%	COM	45257U108