Avoro Capital Advisors LLC Diversified Active

Location: NEW YORK, NY

CIK: 0001633313 · Show all filings

Period: Q4 2019 (← Previous) (Next →)

Filing Date: Feb 14, 2020

Total Value ($000): $3,405,658 (100.0% shares, 0.0% debt)

Holdings (31)

— IMMUNOMEDICS INC 15.2%

Value ($000) $518,420 Shares 24,500,000 Est. Cost $10.77 Unrealized —

— MIRATI THERAPEUTICS INC 14.6%

Value ($000) $496,137 Shares 3,850,200 Est. Cost $21.82 Unrealized —

ASND ASCENDIS PHARMA 7.6%

Value ($000) $259,459 Shares 1,865,000 Est. Cost $42.74 Unrealized —

IOVA IOVANCE BIOTHERAPEUTICS INC 7.2%

Value ($000) $244,305 Shares 8,826,039 Est. Cost $10.01 Unrealized +127.2%

SRPT SAREPTA THERAPEUTICS INC 6.7%

Value ($000) $227,110 Shares 1,760,000 Est. Cost $106.97 Unrealized -5.6%

— CONSTELLATION PHARMACEUTICALS INC 5.0%

Value ($000) $171,952 Shares 3,650,000 Est. Cost $47.11 Unrealized —

BMRN BIOMARIN PHARMACEUTICAL INC 5.0%

Value ($000) $169,100 Shares 2,000,000 Est. Cost $84.64 Unrealized -10.8%

ARGX ARGENX SE 4.4%

Value ($000) $150,327 Shares 936,500 Est. Cost $62.11 Unrealized —

— HORIZON THERAPEUTICS PLC 4.3%

Value ($000) $144,800 Shares 4,000,000 Est. Cost $24.06 Unrealized —

QURE UNIQURE NV 3.6%

Value ($000) $121,822 Shares 1,700,000 Est. Cost $55.50 Unrealized -1.1%

— KARYOPHARM THERAPEUTICS INC 3.3%

Value ($000) $113,103 Shares 5,900,000 Est. Cost $9.62 Unrealized —

— MYOKARDIA INC 3.3%

Value ($000) $112,243 Shares 1,540,000 Est. Cost $51.56 Unrealized —

FOLD AMICUS THERAPEUTICS INC 3.2%

Value ($000) $109,088 Shares 11,200,000 Est. Cost $10.45 Unrealized -12.4%

— ZOGENIX INC 3.1%

Value ($000) $104,260 Shares 2,000,000 Est. Cost $38.83 Unrealized —

— ATHENEX INC 2.4%

Value ($000) $80,342 Shares 5,261,437 Est. Cost $18.13 Unrealized —

— ADVERUM BIOTECHNOLOGIES INC 1.8%

Value ($000) $60,480 Shares 5,250,000 Est. Cost $10.90 Unrealized —

— TRICIDA INC 1.7%

Value ($000) $58,874 Shares 1,560,000 Est. Cost $32.26 Unrealized —

— AMARIN CORP PLC 1.2%

Value ($000) $40,736 Shares 1,900,000 Est. Cost $16.89 Unrealized —

MDGL MADRIGAL PHARMACEUTICALS INC 0.9%

Value ($000) $31,797 Shares 349,000 Est. Cost $153.98 Unrealized -37.0%

XENE XENON PHARMACEUTICALS INC 0.9%

Value ($000) $31,464 Shares 2,400,000 Est. Cost $8.86 Unrealized +18.7%

— DECIPHERA PHARMACEUTICALS INC 0.9%

Value ($000) $31,120 Shares 500,000 Est. Cost $62.24 Unrealized —

CUE CUE BIOPHARMA INC 0.9%

Value ($000) $29,686 Shares 1,870,000 Est. Cost $10.47 Unrealized 0.0%

ALLO ALLOGENE THERAPEUTICS INC 0.9%

Value ($000) $29,321 Shares 1,128,594 Est. Cost $26.57 Unrealized +3.7%

— BIODELIVERY SCIENCES INTL 0.6%

Value ($000) $18,960 Shares 3,000,000 Est. Cost $3.56 Unrealized —

— MARINUS PHARMACEUTICALS INC 0.4%

Value ($000) $13,392 Shares 6,200,000 Est. Cost $2.16 Unrealized —

TGTX TG THERAPEUTICS INC 0.3%

Value ($000) $11,100 Shares 1,000,000 Est. Cost $7.60 Unrealized 0.0%

— CYMABAY THERAPEUTICS INC 0.3%

Value ($000) $10,780 Shares 5,500,000 Est. Cost $5.32 Unrealized —

FENC FENNEC PHARMACEUTICALS INC 0.2%

Value ($000) $7,167 Shares 1,105,999 Est. Cost $11.09 Unrealized -51.5%

— DECIPHERA PHARMACEUTICALS INC 0.1%

Value ($000) $5,010 Shares 800,000 Est. Cost $62.24 Unrealized —

— ALIMERA SCIENCES INC 0.1%

Value ($000) $3,153 Shares 415,999 Est. Cost $7.58 Unrealized —

— SEATTLE GENETICS INC 0.0%

Value ($000) $150 Shares 75,000 Est. Cost — Unrealized —

Ticker	Issuer	Shares	Value ($000)	%	Est. Cost	Unrealized	Class	CUSIP
—	IMMUNOMEDICS INC	24,500,000	$518,420	15.2%	$10.77	—	Common	452907108
—	MIRATI THERAPEUTICS INC	3,850,200	$496,137	14.6%	$21.82	—	Common	60468T105
ASND	ASCENDIS PHARMA	1,865,000	$259,459	7.6%	$42.74	—	Sponsored ADR	04351P101
IOVA	IOVANCE BIOTHERAPEUTICS INC	8,826,039	$244,305	7.2%	$10.01	+127.2%	Common	462260100
SRPT	SAREPTA THERAPEUTICS INC	1,760,000	$227,110	6.7%	$106.97	-5.6%	Common	803607100
—	CONSTELLATION PHARMACEUTICALS INC	3,650,000	$171,952	5.0%	$47.11	—	Common	210373106
BMRN	BIOMARIN PHARMACEUTICAL INC	2,000,000	$169,100	5.0%	$84.64	-10.8%	Common	09061G101
ARGX	ARGENX SE	936,500	$150,327	4.4%	$62.11	—	Sponsored ADR	04016X101
—	HORIZON THERAPEUTICS PLC	4,000,000	$144,800	4.3%	$24.06	—	Common	G46188101
QURE	UNIQURE NV	1,700,000	$121,822	3.6%	$55.50	-1.1%	Common	N90064101
—	KARYOPHARM THERAPEUTICS INC	5,900,000	$113,103	3.3%	$9.62	—	Common	48576U106
—	MYOKARDIA INC	1,540,000	$112,243	3.3%	$51.56	—	Common	62857M105
FOLD	AMICUS THERAPEUTICS INC	11,200,000	$109,088	3.2%	$10.45	-12.4%	Common	03152W109
—	ZOGENIX INC	2,000,000	$104,260	3.1%	$38.83	—	Common	98978L204
—	ATHENEX INC	5,261,437	$80,342	2.4%	$18.13	—	Common	04685N103
—	ADVERUM BIOTECHNOLOGIES INC	5,250,000	$60,480	1.8%	$10.90	—	Common	00773U108
—	TRICIDA INC	1,560,000	$58,874	1.7%	$32.26	—	Common	89610F101
—	AMARIN CORP PLC	1,900,000	$40,736	1.2%	$16.89	—	Sponsored ADR	023111206
MDGL	MADRIGAL PHARMACEUTICALS INC	349,000	$31,797	0.9%	$153.98	-37.0%	Common	558868105
XENE	XENON PHARMACEUTICALS INC	2,400,000	$31,464	0.9%	$8.86	+18.7%	Common	98420N105
—	DECIPHERA PHARMACEUTICALS INC	500,000	$31,120	0.9%	$62.24	—	Common	24344T101
CUE	CUE BIOPHARMA INC	1,870,000	$29,686	0.9%	$10.47	0.0%	Common	22978P106
ALLO	ALLOGENE THERAPEUTICS INC	1,128,594	$29,321	0.9%	$26.57	+3.7%	Common	019770106
—	BIODELIVERY SCIENCES INTL	3,000,000	$18,960	0.6%	$3.56	—	Common	09060J106
—	MARINUS PHARMACEUTICALS INC	6,200,000	$13,392	0.4%	$2.16	—	Common	56854Q101
TGTX	TG THERAPEUTICS INC	1,000,000	$11,100	0.3%	$7.60	0.0%	Common	88322Q108
—	CYMABAY THERAPEUTICS INC	5,500,000	$10,780	0.3%	$5.32	—	Common	23257D103
FENC	FENNEC PHARMACEUTICALS INC	1,105,999	$7,167	0.2%	$11.09	-51.5%	Common	31447P100
—	DECIPHERA PHARMACEUTICALS INC	800,000	$5,010	0.1%	$62.24	—	Call	24344T101
—	ALIMERA SCIENCES INC	415,999	$3,153	0.1%	$7.58	—	Common	016259202
—	SEATTLE GENETICS INC	75,000	$150	0.0%	—	—	Call	812578102