EcoR1 Capital, LLC Quant / Systematic

Location: San Francisco, CA

CIK: 0001587114 · Show all filings

Period: Q1 2015 (← Previous) (Next →)

Filing Date: May 18, 2015

Total Value: $300M (92.7% shares, 7.3% debt)

Holdings (23)

— ATARA BIOTHERAPEUTICS 14.7%

Value $44.2M Shares 1,063,189 Est. Cost $36.04 Unrealized —

— EPIZYME 9.9%

Value $29.68M Shares 1,580,400 Est. Cost $18.78 Unrealized —

— RECEPTOS 8.3%

Value $24.95M Shares 151,301 Est. Cost $124.05 Unrealized —

— ARRAY BIOPHARMA SR CONV NT 3.000% Due 06/01/2020 7.3%

Value $21.97M Shares 17,500,000 Est. Cost $0.93 Unrealized —

— ASSEMBLY BIOSCIENCES 6.9%

Value $20.84M Shares 1,574,107 Est. Cost $9.79 Unrealized —

— CLOVIS ONCOLOGY 6.2%

Value $18.56M Shares 2,500 Est. Cost — Unrealized —

— CLOVIS ONCOLOGY 6.0%

Value $18.04M Shares 243,048 Est. Cost $56.00 Unrealized —

— KITE PHARMA 5.4%

Value $16.23M Shares 281,400 Est. Cost $57.67 Unrealized —

— FLEX PHARMA 5.3%

Value $15.79M Shares 805,691 Est. Cost $19.60 Unrealized —

IRWD IRONWOOD PHARMACEUTICALS CL A 4.8%

Value $14.4M Shares 900,000 Est. Cost $11.44 Unrealized +14.6%

— FIBROGEN 4.2%

Value $12.55M Shares 400,000 Est. Cost $27.34 Unrealized —

— RETROPHIN 3.3%

Value $9.824M Shares 410,000 Est. Cost $23.96 Unrealized —

— KINDRED BIOSCIENCES 3.1%

Value $9.242M Shares 1,294,431 Est. Cost $7.45 Unrealized —

IRWD IRONWOOD PHARMACEUTICALS CL A 2.7%

Value $8M Shares 5,000 Est. Cost $11.44 Unrealized +14.6%

— GENVEC 2.0%

Value $5.86M Shares 1,986,413 Est. Cost $2.08 Unrealized —

— SAGE THERAPEUTICS INC 1.9%

Value $5.649M Shares 112,455 Est. Cost $18.47 Unrealized —

— ARRAY BIOPHARMA 1.8%

Value $5.417M Shares 7,350 Est. Cost — Unrealized —

— CALITHERA BIOSCIENCES 1.6%

Value $4.852M Shares 295,480 Est. Cost $19.00 Unrealized —

— FORWARD PHARMA A/S SPONSORED ADR 1.5%

Value $4.502M Shares 158,985 Est. Cost $23.61 Unrealized —

XENE XENON PHARMACEUTICALS 1.2%

Value $3.72M Shares 220,570 Est. Cost $14.68 Unrealized +25.8%

— FLEXION THERAPEUTICS 1.2%

Value $3.669M Shares 162,900 Est. Cost $22.52 Unrealized —

— TARGACEPT 0.6%

Value $1.841M Shares 619,699 Est. Cost $2.63 Unrealized —

— EPIZYME 0.1%

Value $282K Shares 150 Est. Cost — Unrealized —

Ticker	Issuer	Shares	Value	%	Est. Cost	Unrealized	Class	CUSIP
—	ATARA BIOTHERAPEUTICS	1,063,189	$44.2M	14.7%	$36.04	—	COM	046513107
—	EPIZYME	1,580,400	$29.68M	9.9%	$18.78	—	COM	29428V104
—	RECEPTOS	151,301	$24.95M	8.3%	$124.05	—	COM	756207106
—	ARRAY BIOPHARMA SR CONV NT 3.000% Due 06/01/2020	17,500,000	$21.97M	7.3%	$0.93	—	NOTE	04269XAA3
—	ASSEMBLY BIOSCIENCES	1,574,107	$20.84M	6.9%	$9.79	—	COM	045396108
—	CLOVIS ONCOLOGY	2,500	$18.56M	6.2%	—	—	Put	189464950
—	CLOVIS ONCOLOGY	243,048	$18.04M	6.0%	$56.00	—	COM	189464100
—	KITE PHARMA	281,400	$16.23M	5.4%	$57.67	—	COM	49803L109
—	FLEX PHARMA	805,691	$15.79M	5.3%	$19.60	—	COM	33938A105
IRWD	IRONWOOD PHARMACEUTICALS CL A	900,000	$14.4M	4.8%	$11.44	+14.6%	COM CL A	46333X108
—	FIBROGEN	400,000	$12.55M	4.2%	$27.34	—	COM	31572Q808
—	RETROPHIN	410,000	$9.824M	3.3%	$23.96	—	COM	761299106
—	KINDRED BIOSCIENCES	1,294,431	$9.242M	3.1%	$7.45	—	COM	494577109
IRWD	IRONWOOD PHARMACEUTICALS CL A	5,000	$8M	2.7%	$11.44	+14.6%	Call	46333X108
—	GENVEC	1,986,413	$5.86M	2.0%	$2.08	—	COM	37246C307
—	SAGE THERAPEUTICS INC	112,455	$5.649M	1.9%	$18.47	—	COM	78667J108
—	ARRAY BIOPHARMA	7,350	$5.417M	1.8%	—	—	Call	04269X105
—	CALITHERA BIOSCIENCES	295,480	$4.852M	1.6%	$19.00	—	COM	13089P101
—	FORWARD PHARMA A/S SPONSORED ADR	158,985	$4.502M	1.5%	$23.61	—	SPONSORED ADR	34986J105
XENE	XENON PHARMACEUTICALS	220,570	$3.72M	1.2%	$14.68	+25.8%	COM	98420N105
—	FLEXION THERAPEUTICS	162,900	$3.669M	1.2%	$22.52	—	COM	33938J106
—	TARGACEPT	619,699	$1.841M	0.6%	$2.63	—	COM	87611R306
—	EPIZYME	150	$282K	0.1%	—	—	Call	29428V904