Avoro Capital Advisors LLC Diversified Active

Location: New York, NY

CIK: 0001633313 · Show all filings

Period: Q2 2018 (← Previous) (Next →)

Filing Date: Aug 14, 2018

Total Value: $2.598B (99.9% shares, 0.1% debt)

Holdings (42)

— IMMUNOMEDICS INC 16.1%

Value $419M Shares 17,714,461 Est. Cost $8.14 Unrealized —

— MIRATI THERAPEUTICS INC 9.1%

Value $237M Shares 4,798,101 Est. Cost $18.96 Unrealized —

BMRN BIOMARIN PHARMACEUTICAL INC 5.9%

Value $153M Shares 1,622,770 Est. Cost $86.03 Unrealized +1.8%

FOLD AMICUS THERAPEUTICS INC 5.6%

Value $146M Shares 9,369,150 Est. Cost $10.23 Unrealized +47.8%

ASND ASCENDIS PHARMA 5.3%

Value $137M Shares 2,063,336 Est. Cost $35.68 Unrealized —

MDGL MADRIGAL PHARMACEUTICALS INC 5.3%

Value $137M Shares 489,536 Est. Cost $175.60 Unrealized 0.0%

SRPT SAREPTA THERAPEUTICS INC 4.9%

Value $127M Shares 958,928 Est. Cost $94.31 Unrealized 0.0%

IOVA IOVANCE BIOTHERAPEUTICS INC 4.0%

Value $105M Shares 8,177,720 Est. Cost $9.71 Unrealized +50.6%

— HORIZON PHARMA PLC 3.6%

Value $92.63M Shares 5,593,683 Est. Cost $13.49 Unrealized —

— ENDOCYTE INC 3.0%

Value $78.59M Shares 5,695,200 Est. Cost $9.09 Unrealized —

PTCT PTC THERAPEUTICS INC 3.0%

Value $77.41M Shares 2,294,877 Est. Cost $31.18 Unrealized 0.0%

— SPECTRUM PHARMACEUTICALS INC 2.8%

Value $71.68M Shares 3,419,818 Est. Cost $20.96 Unrealized —

ALNY ALNYLAM PHARMACEUTICALS INC 2.7%

Value $68.95M Shares 700,100 Est. Cost $99.19 Unrealized 0.0%

— ZOGENIX INC 2.6%

Value $66.45M Shares 1,503,313 Est. Cost $37.70 Unrealized —

TGTX TG THERAPEUTICS INC 2.5%

Value $65.09M Shares 4,950,031 Est. Cost $10.23 Unrealized +34.4%

ARGX ARGENX SE 2.5%

Value $64.8M Shares 782,053 Est. Cost $43.79 Unrealized —

PBYI PUMA BIOTECHNOLOGY INC 2.4%

Value $61.18M Shares 1,034,375 Est. Cost $71.46 Unrealized -18.9%

VNDA VANDA PHARMACEUTICALS INC 2.1%

Value $53.34M Shares 2,800,191 Est. Cost $15.29 Unrealized +9.4%

— CLOVIS ONCOLOGY INC 2.0%

Value $52.13M Shares 1,146,436 Est. Cost $74.62 Unrealized —

PCRX PACIRA PHARMACEUTICALS INC 1.8%

Value $46.81M Shares 1,460,610 Est. Cost $38.49 Unrealized -10.3%

VKTX VIKING THERAPEUTICS INC 1.6%

Value $42.43M Shares 4,471,300 Est. Cost $6.65 Unrealized 0.0%

— ASSEMBLY BIOSCIENCES INC 1.5%

Value $37.78M Shares 963,427 Est. Cost $27.25 Unrealized —

— MEDICINES CO 1.4%

Value $35.29M Shares 961,574 Est. Cost $42.25 Unrealized —

— TRICIDA INC 1.3%

Value $32.76M Shares 1,095,764 Est. Cost $29.90 Unrealized —

— GLOBAL BLOOD THERAPEUTICS INC 1.2%

Value $31.66M Shares 700,548 Est. Cost $27.61 Unrealized —

— TELIGENT INC 0.7%

Value $18.34M Shares 5,299,431 Est. Cost $7.35 Unrealized —

— CYMABAY THERAPEUTICS INC 0.7%

Value $17.21M Shares 1,282,374 Est. Cost $13.42 Unrealized —

— DERMIRA INC 0.7%

Value $16.95M Shares 1,841,823 Est. Cost $17.73 Unrealized —

— BIODELIVERY SCIENCES INTL 0.6%

Value $16.04M Shares 5,437,779 Est. Cost $2.57 Unrealized —

CPRX CATALYST PHARMACEUTICALS INC 0.5%

Value $14.03M Shares 4,497,042 Est. Cost $1.81 Unrealized +67.2%

— SESEN BIO INC 0.5%

Value $13.26M Shares 6,800,000 Est. Cost $1.95 Unrealized —

— INTEC PHARMA LTD 0.4%

Value $11.31M Shares 2,570,705 Est. Cost $8.29 Unrealized —

XENE XENON PHARMACEUTICALS INC 0.4%

Value $11.06M Shares 1,202,118 Est. Cost $6.21 Unrealized 0.0%

FENC FENNEC PHARMACEUTICALS INC 0.4%

Value $10.7M Shares 1,022,666 Est. Cost $11.42 Unrealized +3.8%

ARWR ARROWHEAD PHARMACEUTICALS INC 0.2%

Value $6.12M Shares 450,000 Est. Cost $9.35 Unrealized 0.0%

— ALIMERA SCIENCES INC 0.2%

Value $6.106M Shares 6,241,581 Est. Cost $1.43 Unrealized —

— ONCOSEC MEDICAL INC 0.2%

Value $5.531M Shares 4,007,696 Est. Cost $1.88 Unrealized —

XBI SPDR SERIES TRUST - S&P BIOTECH 0.2%

Value $5.3M Shares 1,750,000 Est. Cost — Unrealized —

— AVROBIO INC 0.1%

Value $2.856M Shares 100,000 Est. Cost $28.56 Unrealized —

— PERNIX THERAPEUTICS HOLDINGS INC 0.1%

Value $2.618M Shares 6,000,000 Est. Cost $0.21 Unrealized —

— ONCOBIOLOGICS INC 0.0%

Value $578K Shares 683,531 Est. Cost $3.27 Unrealized —

— ONCOBIOLOGICS INC - WARRANT A 0.0%

Value $12,000 Shares 233,333 Est. Cost $0.46 Unrealized —

Ticker	Issuer	Shares	Value	%	Est. Cost	Unrealized	Class	CUSIP
—	IMMUNOMEDICS INC	17,714,461	$419M	16.1%	$8.14	—	Common	452907108
—	MIRATI THERAPEUTICS INC	4,798,101	$237M	9.1%	$18.96	—	Common	60468T105
BMRN	BIOMARIN PHARMACEUTICAL INC	1,622,770	$153M	5.9%	$86.03	+1.8%	Common	09061G101
FOLD	AMICUS THERAPEUTICS INC	9,369,150	$146M	5.6%	$10.23	+47.8%	Common	03152W109
ASND	ASCENDIS PHARMA	2,063,336	$137M	5.3%	$35.68	—	Sponsored ADR	04351P101
MDGL	MADRIGAL PHARMACEUTICALS INC	489,536	$137M	5.3%	$175.60	0.0%	Common	558868105
SRPT	SAREPTA THERAPEUTICS INC	958,928	$127M	4.9%	$94.31	0.0%	Common	803607100
IOVA	IOVANCE BIOTHERAPEUTICS INC	8,177,720	$105M	4.0%	$9.71	+50.6%	Common	462260100
—	HORIZON PHARMA PLC	5,593,683	$92.63M	3.6%	$13.49	—	Common	G4617B105
—	ENDOCYTE INC	5,695,200	$78.59M	3.0%	$9.09	—	Common	29269A102
PTCT	PTC THERAPEUTICS INC	2,294,877	$77.41M	3.0%	$31.18	0.0%	Common	69366J200
—	SPECTRUM PHARMACEUTICALS INC	3,419,818	$71.68M	2.8%	$20.96	—	Common	84763A108
ALNY	ALNYLAM PHARMACEUTICALS INC	700,100	$68.95M	2.7%	$99.19	0.0%	Common	02043Q107
—	ZOGENIX INC	1,503,313	$66.45M	2.6%	$37.70	—	Common	98978L204
TGTX	TG THERAPEUTICS INC	4,950,031	$65.09M	2.5%	$10.23	+34.4%	Common	88322Q108
ARGX	ARGENX SE	782,053	$64.8M	2.5%	$43.79	—	Sponsored ADR	04016X101
PBYI	PUMA BIOTECHNOLOGY INC	1,034,375	$61.18M	2.4%	$71.46	-18.9%	Common	74587V107
VNDA	VANDA PHARMACEUTICALS INC	2,800,191	$53.34M	2.1%	$15.29	+9.4%	Common	921659108
—	CLOVIS ONCOLOGY INC	1,146,436	$52.13M	2.0%	$74.62	—	Common	189464100
PCRX	PACIRA PHARMACEUTICALS INC	1,460,610	$46.81M	1.8%	$38.49	-10.3%	Common	695127100
VKTX	VIKING THERAPEUTICS INC	4,471,300	$42.43M	1.6%	$6.65	0.0%	Common	92686J106
—	ASSEMBLY BIOSCIENCES INC	963,427	$37.78M	1.5%	$27.25	—	Common	045396108
—	MEDICINES CO	961,574	$35.29M	1.4%	$42.25	—	Common	584688105
—	TRICIDA INC	1,095,764	$32.76M	1.3%	$29.90	—	Common	89610F101
—	GLOBAL BLOOD THERAPEUTICS INC	700,548	$31.66M	1.2%	$27.61	—	Common	37890U108
—	TELIGENT INC	5,299,431	$18.34M	0.7%	$7.35	—	Common	87960W104
—	CYMABAY THERAPEUTICS INC	1,282,374	$17.21M	0.7%	$13.42	—	Common	23257D103
—	DERMIRA INC	1,841,823	$16.95M	0.7%	$17.73	—	Common	24983L104
—	BIODELIVERY SCIENCES INTL	5,437,779	$16.04M	0.6%	$2.57	—	Common	09060J106
CPRX	CATALYST PHARMACEUTICALS INC	4,497,042	$14.03M	0.5%	$1.81	+67.2%	Common	14888U101
—	SESEN BIO INC	6,800,000	$13.26M	0.5%	$1.95	—	Common	817763105
—	INTEC PHARMA LTD	2,570,705	$11.31M	0.4%	$8.29	—	Common	M53644106
XENE	XENON PHARMACEUTICALS INC	1,202,118	$11.06M	0.4%	$6.21	0.0%	Common	98420N105
FENC	FENNEC PHARMACEUTICALS INC	1,022,666	$10.7M	0.4%	$11.42	+3.8%	Common	31447P100
ARWR	ARROWHEAD PHARMACEUTICALS INC	450,000	$6.12M	0.2%	$9.35	0.0%	Common	04280A100
—	ALIMERA SCIENCES INC	6,241,581	$6.106M	0.2%	$1.43	—	Common	016259103
—	ONCOSEC MEDICAL INC	4,007,696	$5.531M	0.2%	$1.88	—	Common	68234L207
XBI	SPDR SERIES TRUST - S&P BIOTECH	1,750,000	$5.3M	0.2%	—	—	Put	78464A870
—	AVROBIO INC	100,000	$2.856M	0.1%	$28.56	—	Common	05455M100
—	PERNIX THERAPEUTICS HOLDINGS INC	6,000,000	$2.618M	0.1%	$0.21	—	Convertible Debt	71426VAK4
—	ONCOBIOLOGICS INC	683,531	$578K	0.0%	$3.27	—	Common	68235M105
—	ONCOBIOLOGICS INC - WARRANT A	233,333	$12,000	0.0%	$0.46	—	Warrant	68235M113