Avoro Capital Advisors LLC Diversified Active

Location: NEW YORK, NY

CIK: 0001633313 · Show all filings

Period: Q4 2018 (← Previous) (Next →)

Filing Date: Feb 14, 2019

Total Value ($000): $1,672,821 (99.8% shares, 0.2% debt)

Holdings (35)

— IMMUNOMEDICS INC 15.1%

Value ($000) $252,785 Shares 17,714,461 Est. Cost $8.14 Unrealized —

— MIRATI THERAPEUTICS INC 12.2%

Value ($000) $203,535 Shares 4,798,101 Est. Cost $18.96 Unrealized —

SRPT SAREPTA THERAPEUTICS INC 8.3%

Value ($000) $139,141 Shares 1,275,000 Est. Cost $102.30 Unrealized +22.2%

ASND ASCENDIS PHARMA 7.4%

Value ($000) $124,047 Shares 1,980,000 Est. Cost $35.68 Unrealized —

BMRN BIOMARIN PHARMACEUTICAL INC 6.9%

Value ($000) $115,804 Shares 1,360,000 Est. Cost $86.03 Unrealized +10.6%

FOLD AMICUS THERAPEUTICS INC 5.8%

Value ($000) $96,998 Shares 10,125,000 Est. Cost $10.29 Unrealized +6.8%

IOVA IOVANCE BIOTHERAPEUTICS INC 5.4%

Value ($000) $90,810 Shares 10,261,039 Est. Cost $9.91 Unrealized -2.7%

— HORIZON PHARMA PLC 5.1%

Value ($000) $84,999 Shares 4,350,000 Est. Cost $13.49 Unrealized —

ARGX ARGENX SE 4.9%

Value ($000) $82,620 Shares 860,000 Est. Cost $50.15 Unrealized —

— AMARIN CORP PLC 4.5%

Value ($000) $75,876 Shares 5,575,000 Est. Cost $15.54 Unrealized —

— ZOGENIX INC 4.3%

Value ($000) $72,009 Shares 1,975,000 Est. Cost $37.38 Unrealized —

— LOXO ONCOLOGY INC 2.7%

Value ($000) $45,523 Shares 325,000 Est. Cost $140.07 Unrealized —

— TRICIDA INC 2.5%

Value ($000) $41,265 Shares 1,750,000 Est. Cost $30.15 Unrealized —

ALLO ALLOGENE THERAPEUTICS INC 1.7%

Value ($000) $27,753 Shares 1,128,584 Est. Cost $26.57 Unrealized 0.0%

MDGL MADRIGAL PHARMACEUTICALS INC 1.5%

Value ($000) $25,362 Shares 225,000 Est. Cost $175.60 Unrealized -11.9%

— ASSEMBLY BIOSCIENCES INC 1.4%

Value ($000) $22,620 Shares 1,000,000 Est. Cost $28.06 Unrealized —

TGTX TG THERAPEUTICS INC 1.2%

Value ($000) $19,475 Shares 4,750,000 Est. Cost $9.62 Unrealized -48.4%

— INTEC PHARMA LTD 1.1%

Value ($000) $18,850 Shares 2,500,000 Est. Cost $8.29 Unrealized —

— BIODELIVERY SCIENCES INTL 1.0%

Value ($000) $17,483 Shares 4,725,000 Est. Cost $2.57 Unrealized —

PCRX PACIRA PHARMACEUTICALS INC 1.0%

Value ($000) $17,208 Shares 400,000 Est. Cost $38.49 Unrealized +21.3%

XENE XENON PHARMACEUTICALS INC 0.9%

Value ($000) $15,144 Shares 2,400,000 Est. Cost $8.86 Unrealized +0.3%

— GLOBAL BLOOD THERAPEUTICS INC 0.9%

Value ($000) $14,368 Shares 350,000 Est. Cost $30.01 Unrealized —

PTCT PTC THERAPEUTICS INC 0.8%

Value ($000) $13,042 Shares 380,000 Est. Cost $31.18 Unrealized +15.3%

ESTA ESTABLISHMENT LABS HOLDINGS INC 0.8%

Value ($000) $13,025 Shares 475,000 Est. Cost $25.66 Unrealized -4.7%

— TELIGENT INC 0.4%

Value ($000) $7,261 Shares 5,300,000 Est. Cost $7.35 Unrealized —

FENC FENNEC PHARMACEUTICALS INC 0.4%

Value ($000) $7,056 Shares 1,105,999 Est. Cost $11.09 Unrealized -37.0%

KOD KODIAK SCIENCES INC 0.4%

Value ($000) $6,406 Shares 902,200 Est. Cost $8.85 Unrealized 0.0%

— Y MABS THERAPEUTICS INC 0.4%

Value ($000) $6,305 Shares 310,000 Est. Cost $26.56 Unrealized —

— ALIMERA SCIENCES INC 0.3%

Value ($000) $4,481 Shares 6,240,000 Est. Cost $1.43 Unrealized —

— PROTEOSTASIS THERAPEUTICS INC 0.3%

Value ($000) $4,212 Shares 1,300,000 Est. Cost $3.24 Unrealized —

— ACER THERAPEUTICS INC 0.2%

Value ($000) $3,018 Shares 150,000 Est. Cost $30.84 Unrealized —

— PERNIX THERAPEUTICS HOLDINGS INC 0.2%

Value ($000) $2,545 Shares 6,000,000 Est. Cost $0.21 Unrealized —

XBI SPDR SERIES TRUST - S&P BIOTECH 0.1%

Value ($000) $1,440 Shares 500,000 Est. Cost — Unrealized —

— OUTLOOK THERAPEUTICS INC 0.0%

Value ($000) $340 Shares 680,000 Est. Cost $0.50 Unrealized —

NBIX NEUROCRINE BIOSCIENCES INC 0.0%

Value ($000) $15 Shares 50,000 Est. Cost — Unrealized —

Ticker	Issuer	Shares	Value ($000)	%	Est. Cost	Unrealized	Class	CUSIP
—	IMMUNOMEDICS INC	17,714,461	$252,785	15.1%	$8.14	—	Common	452907108
—	MIRATI THERAPEUTICS INC	4,798,101	$203,535	12.2%	$18.96	—	Common	60468T105
SRPT	SAREPTA THERAPEUTICS INC	1,275,000	$139,141	8.3%	$102.30	+22.2%	Common	803607100
ASND	ASCENDIS PHARMA	1,980,000	$124,047	7.4%	$35.68	—	Sponsored ADR	04351P101
BMRN	BIOMARIN PHARMACEUTICAL INC	1,360,000	$115,804	6.9%	$86.03	+10.6%	Common	09061G101
FOLD	AMICUS THERAPEUTICS INC	10,125,000	$96,998	5.8%	$10.29	+6.8%	Common	03152W109
IOVA	IOVANCE BIOTHERAPEUTICS INC	10,261,039	$90,810	5.4%	$9.91	-2.7%	Common	462260100
—	HORIZON PHARMA PLC	4,350,000	$84,999	5.1%	$13.49	—	Common	G4617B105
ARGX	ARGENX SE	860,000	$82,620	4.9%	$50.15	—	Sponsored ADR	04016X101
—	AMARIN CORP PLC	5,575,000	$75,876	4.5%	$15.54	—	Sponsored ADR	023111206
—	ZOGENIX INC	1,975,000	$72,009	4.3%	$37.38	—	Common	98978L204
—	LOXO ONCOLOGY INC	325,000	$45,523	2.7%	$140.07	—	Common	548862101
—	TRICIDA INC	1,750,000	$41,265	2.5%	$30.15	—	Common	89610F101
ALLO	ALLOGENE THERAPEUTICS INC	1,128,584	$27,753	1.7%	$26.57	0.0%	Common	019770106
MDGL	MADRIGAL PHARMACEUTICALS INC	225,000	$25,362	1.5%	$175.60	-11.9%	Common	558868105
—	ASSEMBLY BIOSCIENCES INC	1,000,000	$22,620	1.4%	$28.06	—	Common	045396108
TGTX	TG THERAPEUTICS INC	4,750,000	$19,475	1.2%	$9.62	-48.4%	Common	88322Q108
—	INTEC PHARMA LTD	2,500,000	$18,850	1.1%	$8.29	—	Common	M53644106
—	BIODELIVERY SCIENCES INTL	4,725,000	$17,483	1.0%	$2.57	—	Common	09060J106
PCRX	PACIRA PHARMACEUTICALS INC	400,000	$17,208	1.0%	$38.49	+21.3%	Common	695127100
XENE	XENON PHARMACEUTICALS INC	2,400,000	$15,144	0.9%	$8.86	+0.3%	Common	98420N105
—	GLOBAL BLOOD THERAPEUTICS INC	350,000	$14,368	0.9%	$30.01	—	Common	37890U108
PTCT	PTC THERAPEUTICS INC	380,000	$13,042	0.8%	$31.18	+15.3%	Common	69366J200
ESTA	ESTABLISHMENT LABS HOLDINGS INC	475,000	$13,025	0.8%	$25.66	-4.7%	Common	G31249108
—	TELIGENT INC	5,300,000	$7,261	0.4%	$7.35	—	Common	87960W104
FENC	FENNEC PHARMACEUTICALS INC	1,105,999	$7,056	0.4%	$11.09	-37.0%	Common	31447P100
KOD	KODIAK SCIENCES INC	902,200	$6,406	0.4%	$8.85	0.0%	Common	50015M109
—	Y MABS THERAPEUTICS INC	310,000	$6,305	0.4%	$26.56	—	Common	984241109
—	ALIMERA SCIENCES INC	6,240,000	$4,481	0.3%	$1.43	—	Common	016259103
—	PROTEOSTASIS THERAPEUTICS INC	1,300,000	$4,212	0.3%	$3.24	—	Common	74373B109
—	ACER THERAPEUTICS INC	150,000	$3,018	0.2%	$30.84	—	Common	00444P108
—	PERNIX THERAPEUTICS HOLDINGS INC	6,000,000	$2,545	0.2%	$0.21	—	Convertible Debt	71426VAK4
XBI	SPDR SERIES TRUST - S&P BIOTECH	500,000	$1,440	0.1%	—	—	Call	78464A870
—	OUTLOOK THERAPEUTICS INC	680,000	$340	0.0%	$0.50	—	Common	69012T107
NBIX	NEUROCRINE BIOSCIENCES INC	50,000	$15	0.0%	—	—	Call	64125C109