NEXTBio Capital Management LP Concentrated Active

Location: AUSTIN, TX

CIK: 0002038158 · Show all filings

Period: Q1 2026 (← Previous)

Filing Date: May 14, 2026

Total Value ($000): $215,370 (100.0% shares, 0.0% debt)

Holdings (24)

New Positions (1)

SMMT SUMMIT THERAPEUTICS INC 0.8%

Value ($000) $1,701 Shares 89,717 Est. Cost $16.20 Unrealized 0.0%

Ticker	Issuer	Shares	Value ($000)	%	Est. Cost	Unrealized	Class	CUSIP
SMMT	SUMMIT THERAPEUTICS INC	89,717	$1,701	0.8%	$16.20	0.0%	COM	86627T108

Increased Positions (9)

TERN TERNS PHARMACEUTICALS INC 14.8%

Value ($000) $31,871 (+43.1%) Shares 604,534 (+9.7%) Est. Cost $24.38 Unrealized +53.7%

CMPS COMPASS PATHWAYS PLC 5.2%

Value ($000) $11,178 (+115.3%) Shares 2,021,407 (+168.6%) Est. Cost $6.04 Unrealized —

RYTM RHYTHM PHARMACEUTICALS INC 5.1%

Value ($000) $10,965 (+51.6%) Shares 126,078 (+86.5%) Est. Cost $104.57 Unrealized -1.7%

ZBIO ZENAS BIOPHARMA INC 3.9%

Value ($000) $8,343 (-28.6%) Shares 426,736 (+32.5%) Est. Cost $30.19 Unrealized -27.5%

COGT COGENT BIOSCIENCES INC 2.3%

Value ($000) $5,049 (+48.4%) Shares 131,188 (+36.9%) Est. Cost $30.61 Unrealized +22.1%

IVA INVENTIVA SA 3.4%

Value ($000) $7,401 (+22.6%) Shares 1,333,484 (+2.7%) Est. Cost $4.67 Unrealized —

ZLAB ZAI LAB LTD 1.6%

Value ($000) $3,449 (+19.7%) Shares 183,362 (+12.2%) Est. Cost $17.77 Unrealized —

GPCR STRUCTURE THERAPEUTICS INC 3.0%

Value ($000) $6,422 (-2.2%) Shares 133,239 (+41.1%) Est. Cost $63.33 Unrealized —

IRON DISC MEDICINE INC 1.6%

Value ($000) $3,367 (-0.9%) Shares 52,655 (+23.1%) Est. Cost $82.54 Unrealized -10.3%

Ticker	Issuer	Shares	Value ($000)	%	Est. Cost	Unrealized	Class	CUSIP
TERN	TERNS PHARMACEUTICALS INC	604,534 (+9.7%)	$31,871 (+43.1%)	14.8%	$24.38	+53.7%	COM	880881107
CMPS	COMPASS PATHWAYS PLC	2,021,407 (+168.6%)	$11,178 (+115.3%)	5.2%	$6.04	—	SPONSORED ADS	20451W101
RYTM	RHYTHM PHARMACEUTICALS INC	126,078 (+86.5%)	$10,965 (+51.6%)	5.1%	$104.57	-1.7%	COM	76243J105
ZBIO	ZENAS BIOPHARMA INC	426,736 (+32.5%)	$8,343 (-28.6%)	3.9%	$30.19	-27.5%	COM	98937L105
COGT	COGENT BIOSCIENCES INC	131,188 (+36.9%)	$5,049 (+48.4%)	2.3%	$30.61	+22.1%	COM	19240Q201
IVA	INVENTIVA SA	1,333,484 (+2.7%)	$7,401 (+22.6%)	3.4%	$4.67	—	ADS	46124U107
ZLAB	ZAI LAB LTD	183,362 (+12.2%)	$3,449 (+19.7%)	1.6%	$17.77	—	ADR	98887Q104
GPCR	STRUCTURE THERAPEUTICS INC	133,239 (+41.1%)	$6,422 (-2.2%)	3.0%	$63.33	—	SPONSORED ADS	86366E106
IRON	DISC MEDICINE INC	52,655 (+23.1%)	$3,367 (-0.9%)	1.6%	$82.54	-10.3%	COM	254604101

Decreased Positions (3)

ORIC ORIC PHARMACEUTICALS INC 3.1%

Value ($000) $6,634 (+31.7%) Shares 523,619 (-15.0%) Est. Cost $11.51 Unrealized -6.5%

CMPX COMPASS THERAPEUTICS INC 2.1%

Value ($000) $4,487 (-25.0%) Shares 848,204 (-23.9%) Est. Cost $4.62 Unrealized +29.9%

EVMN EVOMMUNE INC 2.0%

Value ($000) $4,232 (+8.3%) Shares 184,063 (-19.4%) Est. Cost $18.78 Unrealized +17.1%

Ticker	Issuer	Shares	Value ($000)	%	Est. Cost	Unrealized	Class	CUSIP
ORIC	ORIC PHARMACEUTICALS INC	523,619 (-15.0%)	$6,634 (+31.7%)	3.1%	$11.51	-6.5%	COM	68622P109
CMPX	COMPASS THERAPEUTICS INC	848,204 (-23.9%)	$4,487 (-25.0%)	2.1%	$4.62	+29.9%	COM	20454B104
EVMN	EVOMMUNE INC	184,063 (-19.4%)	$4,232 (+8.3%)	2.0%	$18.78	+17.1%	COM SHS	30054Y107

Unchanged Positions (11)

STTK SHATTUCK LABS INC 9.4%

Value ($000) $20,254 Shares 3,149,907 Est. Cost $2.39 Unrealized +73.9%

VOR VOR BIOPHARMA INC 8.3%

Value ($000) $17,839 Shares 999,967 Est. Cost $18.62 Unrealized -24.9%

PTGX PROTAGONIST THERAPEUTICS INC 11.2%

Value ($000) $24,202 Shares 229,619 Est. Cost $81.85 Unrealized +1.8%

VSTM VERASTEM INC 3.2%

Value ($000) $6,926 Shares 1,306,800 Est. Cost $8.91 Unrealized -27.3%

CBIO CRESCENT BIOPHARMA INC. 3.2%

Value ($000) $6,849 Shares 372,856 Est. Cost $12.74 Unrealized -13.2%

XENE XENON PHARMACEUTICALS INC 4.9%

Value ($000) $10,655 Shares 183,225 Est. Cost $42.00 Unrealized -0.0%

PVLA PALVELLA THERAPEUTICS INC NE 4.8%

Value ($000) $10,307 Shares 82,686 Est. Cost $85.31 Unrealized +7.1%

PCVX VAXCYTE INC 2.6%

Value ($000) $5,533 Shares 95,223 Est. Cost $44.73 Unrealized +18.0%

OCS OCULIS HOLDING AG 1.8%

Value ($000) $3,978 Shares 149,592 Est. Cost $20.00 Unrealized +32.4%

KALV KALVISTA PHARMACEUTICALS INC 1.2%

Value ($000) $2,653 Shares 131,796 Est. Cost $13.24 Unrealized +17.0%

ACET ADICET BIO INC 0.5%

Value ($000) $1,075 Shares 157,827 Est. Cost $11.05 Unrealized -29.8%

Ticker	Issuer	Shares	Value ($000)	%	Est. Cost	Unrealized	Class	CUSIP
STTK	SHATTUCK LABS INC	3,149,907	$20,254	9.4%	$2.39	+73.9%	COM	82024L103
VOR	VOR BIOPHARMA INC	999,967	$17,839	8.3%	$18.62	-24.9%	COM NEW	929033207
PTGX	PROTAGONIST THERAPEUTICS INC	229,619	$24,202	11.2%	$81.85	+1.8%	COM	74366E102
VSTM	VERASTEM INC	1,306,800	$6,926	3.2%	$8.91	-27.3%	COM NEW	92337C203
CBIO	CRESCENT BIOPHARMA INC.	372,856	$6,849	3.2%	$12.74	-13.2%	COM	G2545C104
XENE	XENON PHARMACEUTICALS INC	183,225	$10,655	4.9%	$42.00	-0.0%	COM	98420N105
PVLA	PALVELLA THERAPEUTICS INC NE	82,686	$10,307	4.8%	$85.31	+7.1%	COM	697947109
PCVX	VAXCYTE INC	95,223	$5,533	2.6%	$44.73	+18.0%	COM	92243G108
OCS	OCULIS HOLDING AG	149,592	$3,978	1.8%	$20.00	+32.4%	ORDINARY SHARES	H5870P102
KALV	KALVISTA PHARMACEUTICALS INC	131,796	$2,653	1.2%	$13.24	+17.0%	COM	483497103
ACET	ADICET BIO INC	157,827	$1,075	0.5%	$11.05	-29.8%	COM NEW	007002207