Ally Bridge Group (NY) LLC Quant / Systematic

Ticker	Issuer	Shares	Value ($000)	%	Est. Cost	Unrealized	Class	CUSIP
ABVX	ABIVAX SA	70,000	$9,440	9.8%	$134.85	—	SPONSORED ADS	00370M103
IVA	INVENTIVA SA	1,500,000	$6,975	7.3%	$4.65	—	ADS	46124U107
NERV	MINERVA NEUROSCIENCES INC	1,655,500	$6,655	6.9%	$3.71	0.0%	COM NEW	603380205
EWTX	EDGEWISE THERAPEUTICS INC	250,000	$6,204	6.5%	$20.07	0.0%	PUT	28036F105
PRAX	PRAXIS PRECISION MEDICINES I	19,882	$5,860	6.1%	$186.22	0.0%	COM NEW	74006W207
EWTX	EDGEWISE THERAPEUTICS INC	195,000	$4,839	5.0%	$20.07	0.0%	COM	28036F105
QURE	UNIQURE NV	200,000	$4,786	5.0%	—	—	CALL	N90064101
OVID	OVID THERAPEUTICS INC	1,785,000	$2,910	3.0%	$1.54	0.0%	COM	690469101
TSHA	TAYSHA GENE THERAPIES INC	500,000	$2,750	2.9%	$2.83	+71.5%	CALL	877619106
PMN	PROMIS NEUROSCIENCES INC	249,339	$1,702	1.8%	$9.76	0.0%	COM SHS	74346M505

Exited Positions (16)

SLNO SOLENO THERAPEUTICS INC 17.6%

Value ($000) $16,900 Shares 250,000 Est. Cost $65.05 Unrealized -15.7%

MDGL MADRIGAL PHARMACEUTICALS INC 15.6%

Value ($000) $14,981 Shares 32,662 Est. Cost $373.08 Unrealized +36.9%

ASND ASCENDIS PHARMA A/S - ADR 10.6%

Value ($000) $10,155 Shares 51,080 Est. Cost $198.81 Unrealized —

LENZ LENZ THERAPEUTICS INC 8.5%

Value ($000) $8,168 Shares 175,363 Est. Cost $27.20 Unrealized +7.2%

AMLX AMYLYX PHARMACEUTICALS INC 6.2%

Value ($000) $5,944 Shares 437,391 Est. Cost $9.41 Unrealized +44.3%

CMPS COMPASS PATHWAYS PLC 6.1%

Value ($000) $5,881 Shares 1,026,382 Est. Cost $2.80 Unrealized —

PRAX PRAXIS PRECISION MEDICINES I 5.5%

Value ($000) $5,300 Shares 100,000 Est. Cost $186.22 Unrealized 0.0%

MNPR MONOPAR THERAPEUTICS INC 5.5%

Value ($000) $5,264 Shares 64,455 Est. Cost $40.21 Unrealized +103.2%

ARQT ARCUTIS BIOTHERAPEUTICS INC 4.6%

Value ($000) $4,396 Shares 233,220 Est. Cost $15.77 Unrealized +62.3%

— MIND MEDICINE MINDMED INC 4.4%

Value ($000) $4,261 Shares 361,444 Est. Cost $7.76 Unrealized —

TARS TARSUS PHARMACEUTICALS INC 4.4%

Value ($000) $4,206 Shares 70,778 Est. Cost $28.11 Unrealized +165.7%

— PROMIS NEUROSCIENCES INC 2.8%

Value ($000) $2,649 Shares 6,233,497 Est. Cost $0.65 Unrealized —

AVTX AVALO THERAPEUTICS INC 2.4%

Value ($000) $2,264 Shares 178,100 Est. Cost $8.60 Unrealized +96.3%

TECX TECTONIC THERAPEUTIC INC 2.3%

Value ($000) $2,175 Shares 138,595 Est. Cost $30.22 Unrealized -38.5%

MLTX MOONLAKE IMMUNOTHERAPEUTICS 0.5%

Value ($000) $495 Shares 69,000 Est. Cost — Unrealized —

ATYR ATYR PHARMA INC 0.5%

Value ($000) $433 Shares 600,000 Est. Cost — Unrealized —

Ticker	Issuer	Shares	Value ($000)	%	Est. Cost	Unrealized	Class	CUSIP
SLNO	SOLENO THERAPEUTICS INC	250,000	$16,900	17.6%	$65.05	-15.7%	CALL	834203309
MDGL	MADRIGAL PHARMACEUTICALS INC	32,662	$14,981	15.6%	$373.08	+36.9%	—	558868105
ASND	ASCENDIS PHARMA A/S - ADR	51,080	$10,155	10.6%	$198.81	—	—	04351P101
LENZ	LENZ THERAPEUTICS INC	175,363	$8,168	8.5%	$27.20	+7.2%	—	52635N103
AMLX	AMYLYX PHARMACEUTICALS INC	437,391	$5,944	6.2%	$9.41	+44.3%	—	03237H101
CMPS	COMPASS PATHWAYS PLC	1,026,382	$5,881	6.1%	$2.80	—	—	20451W101
PRAX	PRAXIS PRECISION MEDICINES I	100,000	$5,300	5.5%	$186.22	0.0%	CALL	74006W207
MNPR	MONOPAR THERAPEUTICS INC	64,455	$5,264	5.5%	$40.21	+103.2%	—	61023L207
ARQT	ARCUTIS BIOTHERAPEUTICS INC	233,220	$4,396	4.6%	$15.77	+62.3%	—	03969K108
—	MIND MEDICINE MINDMED INC	361,444	$4,261	4.4%	$7.76	—	—	60255C885
TARS	TARSUS PHARMACEUTICALS INC	70,778	$4,206	4.4%	$28.11	+165.7%	—	87650L103
—	PROMIS NEUROSCIENCES INC	6,233,497	$2,649	2.8%	$0.65	—	—	74346M406
AVTX	AVALO THERAPEUTICS INC	178,100	$2,264	2.4%	$8.60	+96.3%	—	05338F306
TECX	TECTONIC THERAPEUTIC INC	138,595	$2,175	2.3%	$30.22	-38.5%	—	878972108
MLTX	MOONLAKE IMMUNOTHERAPEUTICS	69,000	$495	0.5%	—	—	CALL	61559X104
ATYR	ATYR PHARMA INC	600,000	$433	0.5%	—	—	CALL	002120202

Decreased Positions (7)

SLNO SOLENO THERAPEUTICS INC 8.1%

Value ($000) $7,780 (-62.0%) Shares 168,029 (-44.5%) Est. Cost $65.05 Unrealized -15.7%

— ATAI BECKLEY NV 7.3%

Value ($000) $7,007 (-42.1%) Shares 1,713,105 (-25.1%) Est. Cost $5.29 Unrealized —

TSHA TAYSHA GENE THERAPIES INC 2.6%

Value ($000) $2,514 (-59.5%) Shares 457,132 (-75.9%) Est. Cost $2.83 Unrealized +71.5%

REPL REPLIMUNE GROUP INC 12.2%

Value ($000) $11,664 (-22.7%) Shares 1,200,000 (-66.7%) Est. Cost — Unrealized —

EPRX EUPRAXIA PHARMACEUTICALS INC 3.1%

Value ($000) $3,004 (-44.4%) Shares 397,895 (-56.5%) Est. Cost $5.44 Unrealized +13.3%

SLDB SOLID BIOSCIENCES INC 2.4%

Value ($000) $2,333 (-31.2%) Shares 413,625 (-24.7%) Est. Cost $3.54 Unrealized +53.3%

CMPS COMPASS PATHWAYS PLC 7.9%

Value ($000) $7,590 (+15.6%) Shares 1,100,000 (-4.0%) Est. Cost $2.80 Unrealized —

Ticker	Issuer	Shares	Value ($000)	%	Est. Cost	Unrealized	Class	CUSIP
SLNO	SOLENO THERAPEUTICS INC	168,029 (-44.5%)	$7,780 (-62.0%)	8.1%	$65.05	-15.7%	COM	834203309
—	ATAI BECKLEY NV	1,713,105 (-25.1%)	$7,007 (-42.1%)	7.3%	$5.29	—	SHS	N0731H103
TSHA	TAYSHA GENE THERAPIES INC	457,132 (-75.9%)	$2,514 (-59.5%)	2.6%	$2.83	+71.5%	COM SHS	877619106
REPL	REPLIMUNE GROUP INC	1,200,000 (-66.7%)	$11,664 (-22.7%)	12.2%	—	—	CALL	76029N106
EPRX	EUPRAXIA PHARMACEUTICALS INC	397,895 (-56.5%)	$3,004 (-44.4%)	3.1%	$5.44	+13.3%	COM	29842P105
SLDB	SOLID BIOSCIENCES INC	413,625 (-24.7%)	$2,333 (-31.2%)	2.4%	$3.54	+53.3%	COM NEW	83422E204
CMPS	COMPASS PATHWAYS PLC	1,100,000 (-4.0%)	$7,590 (+15.6%)	7.9%	$2.80	—	CALL	20451W101

Unchanged Positions (1)

WHWK WHITEHAWK THERAPEUTICS INC 2.1%

Value ($000) $1,979 Shares 817,939 Est. Cost $2.27 Unrealized +1.3%

Ticker	Issuer	Shares	Value ($000)	%	Est. Cost	Unrealized	Class	CUSIP
WHWK	WHITEHAWK THERAPEUTICS INC	817,939	$1,979	2.1%	$2.27	+1.3%	COM	00032Q104