Omega Fund Management, LLC Long-Term Concentrated

Location: Boston, MA

CIK: 0001637359 · Show all filings

Period: Q1 2026 (← Previous)

Filing Date: May 15, 2026

Total Value: $163M (100.0% shares, 0.0% debt)

Holdings (10)

Increased Positions (1)

BCAX Bicara Therapeutics Inc. 29.2%

Value $47.58M (+28.2%) Shares 2,392,150 (+8.5%) Est. Cost — Unrealized —

Ticker	Issuer	Shares	Value	%	Est. Cost	Unrealized	Class	CUSIP
BCAX	Bicara Therapeutics Inc.	2,392,150 (+8.5%)	$47.58M (+28.2%)	29.2%	—	—	Common Stock	055477103

Exited Positions (1)

UPB Upstream Bio Inc. 22.1%

Value $36.01M Shares 1,326,293 Est. Cost — Unrealized —

Ticker	Issuer	Shares	Value	%	Est. Cost	Unrealized	Class	CUSIP
UPB	Upstream Bio Inc.	1,326,293	$36.01M	22.1%	—	—	—	91678A107

Decreased Positions (2)

KMTS Kestra Med Technologies Ltd 12.5%

Value $20.37M (-44.1%) Shares 1,022,149 (-25.6%) Est. Cost — Unrealized —

ALMS Alumis Inc. 3.3%

Value $5.315M (-16.6%) Shares 241,255 (-63.1%) Est. Cost — Unrealized —

Ticker	Issuer	Shares	Value	%	Est. Cost	Unrealized	Class	CUSIP
KMTS	Kestra Med Technologies Ltd	1,022,149 (-25.6%)	$20.37M (-44.1%)	12.5%	—	—	Common Stock	G52441105
ALMS	Alumis Inc.	241,255 (-63.1%)	$5.315M (-16.6%)	3.3%	—	—	Common Stock	022307102

Unchanged Positions (7)

NUVB Nuvation Bio Inc. 21.2%

Value $34.67M Shares 8,081,089 Est. Cost — Unrealized —

BBNX Beta Bionics Inc. 8.1%

Value $13.19M Shares 1,316,183 Est. Cost — Unrealized —

BBOT BridgeBio Oncology Therapeutics Inc. 18.0%

Value $29.44M Shares 3,289,661 Est. Cost — Unrealized —

ENGN enGene Holdings Inc. 3.7%

Value $5.968M Shares 876,357 Est. Cost — Unrealized —

SANA Sana Biotechnology, Inc. 1.5%

Value $2.43M Shares 843,750 Est. Cost — Unrealized —

IMA ImageneBio, Inc. 1.4%

Value $2.277M Shares 455,361 Est. Cost — Unrealized —

REPL Replimune Group 1.2%

Value $1.91M Shares 248,672 Est. Cost — Unrealized —

Ticker	Issuer	Shares	Value	%	Est. Cost	Unrealized	Class	CUSIP
NUVB	Nuvation Bio Inc.	8,081,089	$34.67M	21.2%	—	—	Common Stock Class A	67080N101
BBNX	Beta Bionics Inc.	1,316,183	$13.19M	8.1%	—	—	Common Stock	08659B102
BBOT	BridgeBio Oncology Therapeutics Inc.	3,289,661	$29.44M	18.0%	—	—	Common Stock	107924102
ENGN	enGene Holdings Inc.	876,357	$5.968M	3.7%	—	—	Common Stock	29286M105
SANA	Sana Biotechnology, Inc.	843,750	$2.43M	1.5%	—	—	Common Stock	799566104
IMA	ImageneBio, Inc.	455,361	$2.277M	1.4%	—	—	Common Stock	45175G207
REPL	Replimune Group	248,672	$1.91M	1.2%	—	—	Common Stock	76029N106