TCG Crossover Management, LLC Diversified Active

Location: Palo Alto, CA

CIK: 0001839948 · Show all filings

Period: Q4 2023 (← Previous) (Next →)

Filing Date: Feb 14, 2024

Total Value: $902M (100.0% shares, 0.0% debt)

Holdings (29)

GPCR STRUCTURE THERAPEUTICS INC 9.5%

Value $85.99M Shares 2,109,584 Share Price $40.76 Est. Cost/Share $43.22 Unrealized @ Report Date —

— INHIBRX,INC 7.4%

Value $66.51M Shares 1,750,387 Share Price $38.00 Est. Cost/Share $18.35 Unrealized @ Report Date —

— ICOSAVAX INC 6.5%

Value $58.37M Shares 3,703,704 Share Price $15.76 Est. Cost/Share $9.93 Unrealized @ Report Date —

ANTX AN2 Therapeutics, Inc. 6.1%

Value $54.88M Shares 2,678,209 Share Price $20.49 * Est. Cost/Share $9.33 Unrealized @ Report Date +79.2%

— RAYZEBIO, INC. 6.0%

Value $54.08M Shares 869,908 Share Price $62.17 Est. Cost/Share $22.20 Unrealized @ Report Date —

— AEROVATE THERAPEUTICS INC 5.5%

Value $49.81M Shares 2,201,274 Share Price $22.63 Est. Cost/Share $15.75 Unrealized @ Report Date —

GERN GERON CORP 5.5%

Value $49.32M Shares 23,375,839 Share Price $2.11 * Est. Cost/Share $1.89 Unrealized @ Report Date +3.1%

SVRA SAVARA INC. 5.2%

Value $47M Shares 10,000,000 Share Price $4.70 * Est. Cost/Share $3.56 Unrealized @ Report Date +7.5%

— GRACELL BIOTECHNOLOGIES INC. 5.0%

Value $45.33M Shares 4,514,786 Share Price $10.04 Est. Cost/Share $5.22 Unrealized @ Report Date —

MDGL MADRIGAL PHARMACEUTICALS INC 4.6%

Value $41.63M Shares 179,917 Share Price $231.38 * Est. Cost/Share $110.42 Unrealized @ Report Date +58.5%

KALV KALVISTA PHARMACEUTICALS, INC 4.6%

Value $41.59M Shares 3,395,495 Share Price $12.25 * Est. Cost/Share $5.36 Unrealized @ Report Date +69.8%

SLN SILENCE THERAPEUTICS PLC 4.1%

Value $36.56M Shares 2,104,875 Share Price $17.37 Est. Cost/Share $10.03 Unrealized @ Report Date —

CMPS COMPASS PATHWAYS PLC 3.7%

Value $33.76M Shares 3,858,000 Share Price $8.75 Est. Cost/Share $7.40 Unrealized @ Report Date —

COGT COGENT BIOSCIENCES INC 3.7%

Value $33.11M Shares 5,631,042 Share Price $5.88 * Est. Cost/Share $9.54 Unrealized @ Report Date -19.7%

TYRA TYRA BIOSCIENCES INC 3.1%

Value $27.55M Shares 1,989,103 Share Price $13.85 * Est. Cost/Share $12.71 Unrealized @ Report Date +1.9%

— TOURMALINE BIO INC 2.9%

Value $26.39M Shares 1,007,902 Share Price $26.18 Est. Cost/Share $26.18 Unrealized @ Report Date —

TARS TARSUS PHARMACEUTICALS, INC. 2.6%

Value $23.14M Shares 1,142,857 Share Price $20.25 * Est. Cost/Share $17.70 Unrealized @ Report Date -5.6%

DYN DYNE THERAPEUTICS, INC 2.4%

Value $21.95M Shares 1,650,150 Share Price $13.30 * Est. Cost/Share $12.99 Unrealized @ Report Date -24.8%

KURA KURA ONCOLOGY INC 2.3%

Value $20.47M Shares 1,423,642 Share Price $14.38 * Est. Cost/Share $14.54 Unrealized @ Report Date -32.4%

CNTA CENTESSA PHARMACEUTICALS PLC 1.8%

Value $16.24M Shares 2,040,816 Share Price $7.96 Est. Cost/Share $6.47 Unrealized @ Report Date —

— VISTAGEN THERAPEUTICS INC 1.5%

Value $13.76M Shares 2,676,580 Share Price $5.14 Est. Cost/Share $5.14 Unrealized @ Report Date —

ABVX Abivax SA 1.3%

Value $11.77M Shares 1,100,000 Share Price $10.70 Est. Cost/Share $10.70 Unrealized @ Report Date —

CABA CABALETTA BIO, INC 1.2%

Value $11.05M Shares 486,795 Share Price $22.70 * Est. Cost/Share $3.64 Unrealized @ Report Date +361.8%

TRDA ENTRADA THERAPEUTICS INC 1.0%

Value $8.827M Shares 584,955 Share Price $15.09 Est. Cost/Share $17.12 Unrealized @ Report Date —

NRIX NURIX THERAPEUTICS INC 0.8%

Value $7.406M Shares 717,654 Share Price $10.32 * Est. Cost/Share $6.85 Unrealized @ Report Date 0.0%

CCCC C4 THERAPEUTICS, INC. 0.8%

Value $7.213M Shares 1,276,574 Share Price $5.65 * Est. Cost/Share $5.83 Unrealized @ Report Date -60.9%

TSHA TAYSHA GENE THERAPIES, INC. 0.6%

Value $5.156M Shares 2,912,861 Share Price $1.77 * Est. Cost/Share $1.87 Unrealized @ Report Date +6.7%

VTYX VENTYX BIOSCIENCES, INC 0.2%

Value $2.015M Shares 815,724 Share Price $2.47 * Est. Cost/Share $29.94 Unrealized @ Report Date -68.3%

KOD KODIAK SCIENCES INC 0.1%

Value $815K Shares 267,941 Share Price $3.04 * Est. Cost/Share $2.22 Unrealized @ Report Date 0.0%

Ticker	Issuer	Shares	Value	%	Share Price	Est. Cost/Share	Unrealized @ Report Date	Class	CUSIP
GPCR	STRUCTURE THERAPEUTICS INC	2,109,584	$85.99M	9.5%	$40.76	$43.22	—	ADRS	86366E106
—	INHIBRX,INC	1,750,387	$66.51M	7.4%	$38.00	$18.35	—	COMM	45720L107
—	ICOSAVAX INC	3,703,704	$58.37M	6.5%	$15.76	$9.93	—	COMM	45114M109
ANTX	AN2 Therapeutics, Inc.	2,678,209	$54.88M	6.1%	$20.49 *	$9.33	+79.2%	COMM	037326105
—	RAYZEBIO, INC.	869,908	$54.08M	6.0%	$62.17	$22.20	—	COMM	75525N107
—	AEROVATE THERAPEUTICS INC	2,201,274	$49.81M	5.5%	$22.63	$15.75	—	COMM	008064107
GERN	GERON CORP	23,375,839	$49.32M	5.5%	$2.11 *	$1.89	+3.1%	COMM	374163103
SVRA	SAVARA INC.	10,000,000	$47M	5.2%	$4.70 *	$3.56	+7.5%	COMM	805111101
—	GRACELL BIOTECHNOLOGIES INC.	4,514,786	$45.33M	5.0%	$10.04	$5.22	—	ADRS	38406L103
MDGL	MADRIGAL PHARMACEUTICALS INC	179,917	$41.63M	4.6%	$231.38 *	$110.42	+58.5%	COMM	558868105
KALV	KALVISTA PHARMACEUTICALS, INC	3,395,495	$41.59M	4.6%	$12.25 *	$5.36	+69.8%	COMM	483497103
SLN	SILENCE THERAPEUTICS PLC	2,104,875	$36.56M	4.1%	$17.37	$10.03	—	ADRS	82686Q101
CMPS	COMPASS PATHWAYS PLC	3,858,000	$33.76M	3.7%	$8.75	$7.40	—	ADRS	20451W101
COGT	COGENT BIOSCIENCES INC	5,631,042	$33.11M	3.7%	$5.88 *	$9.54	-19.7%	COMM	19240Q201
TYRA	TYRA BIOSCIENCES INC	1,989,103	$27.55M	3.1%	$13.85 *	$12.71	+1.9%	COMM	90240B106
—	TOURMALINE BIO INC	1,007,902	$26.39M	2.9%	$26.18	$26.18	—	COMM	89157D105
TARS	TARSUS PHARMACEUTICALS, INC.	1,142,857	$23.14M	2.6%	$20.25 *	$17.70	-5.6%	COMM	87650L103
DYN	DYNE THERAPEUTICS, INC	1,650,150	$21.95M	2.4%	$13.30 *	$12.99	-24.8%	COMM	26818M108
KURA	KURA ONCOLOGY INC	1,423,642	$20.47M	2.3%	$14.38 *	$14.54	-32.4%	COMM	50127T109
CNTA	CENTESSA PHARMACEUTICALS PLC	2,040,816	$16.24M	1.8%	$7.96	$6.47	—	COMM	152309100
—	VISTAGEN THERAPEUTICS INC	2,676,580	$13.76M	1.5%	$5.14	$5.14	—	COMM	92840H202
ABVX	Abivax SA	1,100,000	$11.77M	1.3%	$10.70	$10.70	—	COMM	00370M103
CABA	CABALETTA BIO, INC	486,795	$11.05M	1.2%	$22.70 *	$3.64	+361.8%	COMM	12674W109
TRDA	ENTRADA THERAPEUTICS INC	584,955	$8.827M	1.0%	$15.09	$17.12	—	COMM	29384C108
NRIX	NURIX THERAPEUTICS INC	717,654	$7.406M	0.8%	$10.32 *	$6.85	0.0%	COMM	67080M103
CCCC	C4 THERAPEUTICS, INC.	1,276,574	$7.213M	0.8%	$5.65 *	$5.83	-60.9%	COMM	12529R107
TSHA	TAYSHA GENE THERAPIES, INC.	2,912,861	$5.156M	0.6%	$1.77 *	$1.87	+6.7%	COMM	877619106
VTYX	VENTYX BIOSCIENCES, INC	815,724	$2.015M	0.2%	$2.47 *	$29.94	-68.3%	COMM	92332V107
KOD	KODIAK SCIENCES INC	267,941	$815K	0.1%	$3.04 *	$2.22	0.0%	COMM	50015M109