Ghost Tree Capital, LLC Hedge Fund

CIK: 0001595851 · Show all filings

Period: Q2 2020 (← Previous) (Next →)

Filing Date: Aug 14, 2020

Total Value: $379M (100.0% shares, 0.0% debt)

Holdings (43)

XBI SPDR SER TR 8.9%

Value $33.59M Shares 300,000 Est. Cost — Unrealized —

— IMMUNOMEDICS INC 5.4%

Value $20.38M Shares 575,000 Est. Cost $11.44 Unrealized —

SPY SPDR S&P 500 ETF TR 5.3%

Value $20.04M Shares 65,000 Est. Cost — Unrealized —

— CONSTELLATION PHARMCETICLS I 5.2%

Value $19.53M Shares 650,000 Est. Cost $45.31 Unrealized —

— ADVERUM BIOTECHNOLOGIES INC 5.0%

Value $18.79M Shares 900,000 Est. Cost $5.88 Unrealized —

— MIRATI THERAPEUTICS INC 4.7%

Value $17.7M Shares 155,000 Est. Cost $82.63 Unrealized —

IOVA IOVANCE BIOTHERAPEUTICS INC 4.2%

Value $15.92M Shares 580,000 Est. Cost $24.73 Unrealized +32.9%

— MERSANA THERAPEUTICS INC 3.9%

Value $14.63M Shares 625,000 Est. Cost $5.79 Unrealized —

RCKT ROCKET PHARMACEUTICALS INC 3.6%

Value $13.61M Shares 650,000 Est. Cost $15.79 Unrealized +14.2%

— MOMENTA PHARMACEUTICALS INC 3.4%

Value $12.81M Shares 385,000 Est. Cost $13.20 Unrealized —

IMVT IMMUNOVANT INC 3.4%

Value $12.78M Shares 525,000 Est. Cost $11.17 Unrealized +91.9%

QQQ INVESCO QQQ TR 3.3%

Value $12.36M Shares 50,000 Est. Cost — Unrealized —

— TRILLIUM THERAPEUTICS INC 3.3%

Value $12.34M Shares 1,525,000 Est. Cost $5.90 Unrealized —

TGTX TG THERAPEUTICS INC 3.1%

Value $11.69M Shares 600,000 Est. Cost $14.42 Unrealized +11.7%

— SATSUMA PHARMACEUTICALS INC 2.6%

Value $9.778M Shares 340,000 Est. Cost $26.31 Unrealized —

GILD GILEAD SCIENCES INC 2.5%

Value $9.618M Shares 125,000 Est. Cost $61.47 Unrealized 0.0%

ASND ASCENDIS PHARMA A S 2.5%

Value $9.614M Shares 65,000 Est. Cost $106.36 Unrealized —

BCRX BIOCRYST PHARMACEUTICALS INC 2.4%

Value $9.054M Shares 1,900,000 Est. Cost $4.34 Unrealized -7.9%

AUPH AURINIA PHARMACEUTICALS INC 2.4%

Value $8.938M Shares 550,000 Est. Cost $11.07 Unrealized +44.7%

AXSM AXSOME THERAPEUTICS INC 2.2%

Value $8.228M Shares 100,000 Est. Cost $20.68 Unrealized +272.2%

ACAD ACADIA PHARMACEUTICALS INC 2.1%

Value $7.998M Shares 165,000 Est. Cost $48.00 Unrealized 0.0%

— REATA PHARMACEUTICALS INC 2.1%

Value $7.801M Shares 50,000 Est. Cost $121.68 Unrealized —

— AVADEL PHARMACEUTICALS PLC 1.8%

Value $6.666M Shares 825,000 Est. Cost $8.02 Unrealized —

— MYOVANT SCIENCES LTD 1.6%

Value $6.186M Shares 300,000 Est. Cost $13.68 Unrealized —

AGIO AGIOS PHARMACEUTICALS INC 1.6%

Value $6.15M Shares 115,000 Est. Cost $46.30 Unrealized 0.0%

WVE WAVE LIFE SCIENCES LTD 1.5%

Value $5.569M Shares 535,000 Est. Cost $9.41 Unrealized 0.0%

— SURFACE ONCOLOGY INC 1.2%

Value $4.592M Shares 700,000 Est. Cost $6.56 Unrealized —

— IVERIC BIO INC 1.2%

Value $4.59M Shares 900,000 Est. Cost $7.86 Unrealized —

FATE FATE THERAPEUTICS INC 1.1%

Value $4.289M Shares 125,000 Est. Cost $19.17 Unrealized +55.5%

KALV KALVISTA PHARMACEUTICALS INC 1.1%

Value $4.235M Shares 350,000 Est. Cost $15.74 Unrealized -32.4%

ALDX ALDEYRA THERAPEUTICS INC 1.1%

Value $4.17M Shares 1,000,000 Est. Cost $3.65 Unrealized 0.0%

XENE XENON PHARMACEUTICALS INC 1.1%

Value $4.076M Shares 325,000 Est. Cost $14.24 Unrealized -10.6%

ARVN ARVINAS INC 1.1%

Value $4.025M Shares 120,000 Est. Cost $27.20 Unrealized +56.1%

— HOMOLOGY MEDICINES INC 0.9%

Value $3.57M Shares 235,000 Est. Cost $15.49 Unrealized —

— SELECTA BIOSCIENCES INC 0.7%

Value $2.84M Shares 1,000,000 Est. Cost $2.39 Unrealized —

SNDX SYNDAX PHARMACEUTICALS INC 0.7%

Value $2.742M Shares 185,000 Est. Cost $9.38 Unrealized +62.3%

GILD GILEAD SCIENCES INC 0.5%

Value $1.924M Shares 25,000 Est. Cost $61.47 Unrealized 0.0%

— POLYPID LTD 0.5%

Value $1.803M Shares 100,000 Est. Cost $18.03 Unrealized —

ALT ALTIMMUNE INC 0.4%

Value $1.607M Shares 150,000 Est. Cost $5.49 Unrealized 0.0%

— KINIKSA PHARMACEUTICALS LTD 0.3%

Value $1.274M Shares 50,000 Est. Cost $11.06 Unrealized —

VRAYQ VIEWRAY INC 0.2%

Value $672K Shares 300,000 Est. Cost $5.75 Unrealized -62.9%

MRNA MODERNA INC 0.2%

Value $642K Shares 10,000 Est. Cost $54.76 Unrealized 0.0%

FXE INVESCO CURRENCYSHARES EURO 0.1%

Value $212K Shares 2,000 Est. Cost $104.32 Unrealized —

Ticker	Issuer	Shares	Value	%	Est. Cost	Unrealized	Class	CUSIP
XBI	SPDR SER TR	300,000	$33.59M	8.9%	—	—	Put	78464A870
—	IMMUNOMEDICS INC	575,000	$20.38M	5.4%	$11.44	—	COM	452907108
SPY	SPDR S&P 500 ETF TR	65,000	$20.04M	5.3%	—	—	Put	78462F103
—	CONSTELLATION PHARMCETICLS I	650,000	$19.53M	5.2%	$45.31	—	COM	210373106
—	ADVERUM BIOTECHNOLOGIES INC	900,000	$18.79M	5.0%	$5.88	—	COM	00773U108
—	MIRATI THERAPEUTICS INC	155,000	$17.7M	4.7%	$82.63	—	COM	60468T105
IOVA	IOVANCE BIOTHERAPEUTICS INC	580,000	$15.92M	4.2%	$24.73	+32.9%	COM	462260100
—	MERSANA THERAPEUTICS INC	625,000	$14.63M	3.9%	$5.79	—	COM	59045L106
RCKT	ROCKET PHARMACEUTICALS INC	650,000	$13.61M	3.6%	$15.79	+14.2%	COM	77313F106
—	MOMENTA PHARMACEUTICALS INC	385,000	$12.81M	3.4%	$13.20	—	COM	60877T100
IMVT	IMMUNOVANT INC	525,000	$12.78M	3.4%	$11.17	+91.9%	COM	45258J102
QQQ	INVESCO QQQ TR	50,000	$12.36M	3.3%	—	—	Put	46090E103
—	TRILLIUM THERAPEUTICS INC	1,525,000	$12.34M	3.3%	$5.90	—	COM NEW	89620X506
TGTX	TG THERAPEUTICS INC	600,000	$11.69M	3.1%	$14.42	+11.7%	COM	88322Q108
—	SATSUMA PHARMACEUTICALS INC	340,000	$9.778M	2.6%	$26.31	—	COM	80405P107
GILD	GILEAD SCIENCES INC	125,000	$9.618M	2.5%	$61.47	0.0%	Call	375558103
ASND	ASCENDIS PHARMA A S	65,000	$9.614M	2.5%	$106.36	—	SPONSORED ADR	04351P101
BCRX	BIOCRYST PHARMACEUTICALS INC	1,900,000	$9.054M	2.4%	$4.34	-7.9%	COM	09058V103
AUPH	AURINIA PHARMACEUTICALS INC	550,000	$8.938M	2.4%	$11.07	+44.7%	COM	05156V102
AXSM	AXSOME THERAPEUTICS INC	100,000	$8.228M	2.2%	$20.68	+272.2%	COM	05464T104
ACAD	ACADIA PHARMACEUTICALS INC	165,000	$7.998M	2.1%	$48.00	0.0%	COM	004225108
—	REATA PHARMACEUTICALS INC	50,000	$7.801M	2.1%	$121.68	—	CL A	75615P103
—	AVADEL PHARMACEUTICALS PLC	825,000	$6.666M	1.8%	$8.02	—	SPONSORED ADR	05337M104
—	MYOVANT SCIENCES LTD	300,000	$6.186M	1.6%	$13.68	—	COM	G637AM102
AGIO	AGIOS PHARMACEUTICALS INC	115,000	$6.15M	1.6%	$46.30	0.0%	COM	00847X104
WVE	WAVE LIFE SCIENCES LTD	535,000	$5.569M	1.5%	$9.41	0.0%	SHS	Y95308105
—	SURFACE ONCOLOGY INC	700,000	$4.592M	1.2%	$6.56	—	COM	86877M209
—	IVERIC BIO INC	900,000	$4.59M	1.2%	$7.86	—	COM	46583P102
FATE	FATE THERAPEUTICS INC	125,000	$4.289M	1.1%	$19.17	+55.5%	COM	31189P102
KALV	KALVISTA PHARMACEUTICALS INC	350,000	$4.235M	1.1%	$15.74	-32.4%	COM	483497103
ALDX	ALDEYRA THERAPEUTICS INC	1,000,000	$4.17M	1.1%	$3.65	0.0%	COM	01438T106
XENE	XENON PHARMACEUTICALS INC	325,000	$4.076M	1.1%	$14.24	-10.6%	COM	98420N105
ARVN	ARVINAS INC	120,000	$4.025M	1.1%	$27.20	+56.1%	COM	04335A105
—	HOMOLOGY MEDICINES INC	235,000	$3.57M	0.9%	$15.49	—	COM	438083107
—	SELECTA BIOSCIENCES INC	1,000,000	$2.84M	0.7%	$2.39	—	COM	816212104
SNDX	SYNDAX PHARMACEUTICALS INC	185,000	$2.742M	0.7%	$9.38	+62.3%	COM	87164F105
GILD	GILEAD SCIENCES INC	25,000	$1.924M	0.5%	$61.47	0.0%	COM	375558103
—	POLYPID LTD	100,000	$1.803M	0.5%	$18.03	—	SHS	M8001Q118
ALT	ALTIMMUNE INC	150,000	$1.607M	0.4%	$5.49	0.0%	COM NEW	02155H200
—	KINIKSA PHARMACEUTICALS LTD	50,000	$1.274M	0.3%	$11.06	—	COM CL A	G5269C101
VRAYQ	VIEWRAY INC	300,000	$672K	0.2%	$5.75	-62.9%	COM	92672L107
MRNA	MODERNA INC	10,000	$642K	0.2%	$54.76	0.0%	COM	60770K107
FXE	INVESCO CURRENCYSHARES EURO	2,000	$212K	0.1%	$104.32	—	EURO SHS	46138K103