Ghost Tree Capital, LLC Hedge Fund

CIK: 0001595851 · Show all filings

Period: Q3 2023 (← Previous) (Next →)

Filing Date: Nov 14, 2023

Total Value: $304M (100.0% shares, 0.0% debt)

Holdings (69)

XBI SPDR SER TR 7.2%
Value $21.91M Shares 300,000 Share Price $73.02 Est. Cost/Share — Unrealized @ Report Date —
MLTX MOONLAKE IMMUNOTHERAPEUTICS 6.2%
Value $18.81M Shares 330,000 Share Price $57.00 * Est. Cost/Share $20.94 Unrealized @ Report Date +163.6%
SRPT SAREPTA THERAPEUTICS INC 6.0%
Value $18.18M Shares 150,000 Share Price $121.22 * Est. Cost/Share $96.08 Unrealized @ Report Date +17.6%
MLTX MOONLAKE IMMUNOTHERAPEUTICS 4.7%
Value $14.25M Shares 250,000 Share Price $57.00 * Est. Cost/Share $20.94 Unrealized @ Report Date +163.6%
— AKERO THERAPEUTICS INC 4.2%
Value $12.64M Shares 250,000 Share Price $50.58 Est. Cost/Share $44.16 Unrealized @ Report Date —
KRYS KRYSTAL BIOTECH INC 3.1%
Value $9.28M Shares 80,000 Share Price $116.00 * Est. Cost/Share $117.03 Unrealized @ Report Date +4.3%
MDGL MADRIGAL PHARMACEUTICALS INC 2.8%
Value $8.397M Shares 57,500 Share Price $146.04 * Est. Cost/Share $197.50 Unrealized @ Report Date -4.7%
TGTX TG THERAPEUTICS INC 2.7%
Value $8.36M Shares 1,000,000 Share Price $8.36 * Est. Cost/Share $14.97 Unrealized @ Report Date -6.9%
ASND ASCENDIS PHARMA A/S 2.6%
Value $7.959M Shares 85,000 Share Price $93.64 Est. Cost/Share $124.74 Unrealized @ Report Date —
AXSM AXSOME THERAPEUTICS INC 2.5%
Value $7.688M Shares 110,000 Share Price $69.89 * Est. Cost/Share $36.01 Unrealized @ Report Date +107.6%
— ALPINE IMMUNE SCIENCES INC 2.5%
Value $7.604M Shares 664,132 Share Price $11.45 Est. Cost/Share $10.07 Unrealized @ Report Date —
PCVX VAXCYTE INC 2.3%
Value $7.137M Shares 140,000 Share Price $50.98 * Est. Cost/Share $31.83 Unrealized @ Report Date +55.0%
TARS TARSUS PHARMACEUTICALS INC 2.3%
Value $7.108M Shares 400,000 Share Price $17.77 Est. Cost/Share $20.09 Unrealized @ Report Date -11.9%
APLS APELLIS PHARMACEUTICALS INC 2.3%
Value $7.037M Shares 185,000 Share Price $38.04 * Est. Cost/Share $54.54 Unrealized @ Report Date -19.5%
PTGX PROTAGONIST THERAPEUTICS INC 2.2%
Value $6.672M Shares 400,000 Share Price $16.68 * Est. Cost/Share $17.94 Unrealized @ Report Date +8.2%
COGT COGENT BIOSCIENCES INC 2.1%
Value $6.338M Shares 650,000 Share Price $9.75 * Est. Cost/Share $10.99 Unrealized @ Report Date +7.9%
RCKT ROCKET PHARMACEUTICALS INC 2.0%
Value $6.045M Shares 295,000 Share Price $20.49 * Est. Cost/Share $20.20 Unrealized @ Report Date -10.0%
— AMBRX BIOPHARMA INC 2.0%
Value $6.037M Shares 525,000 Share Price $11.50 Est. Cost/Share $10.33 Unrealized @ Report Date —
— AKERO THERAPEUTICS INC 1.9%
Value $5.817M Shares 115,000 Share Price $50.58 Est. Cost/Share $44.16 Unrealized @ Report Date —
IMVT IMMUNOVANT INC 1.6%
Value $4.991M Shares 130,000 Share Price $38.39 * Est. Cost/Share $22.60 Unrealized @ Report Date 0.0%
SRPT SAREPTA THERAPEUTICS INC 1.6%
Value $4.849M Shares 40,000 Share Price $121.22 * Est. Cost/Share $96.08 Unrealized @ Report Date +17.6%
SNDX SYNDAX PHARMACEUTICALS INC 1.4%
Value $4.356M Shares 300,000 Share Price $14.52 * Est. Cost/Share $21.73 Unrealized @ Report Date -12.9%
PMVP PMV PHARMACEUTICALS INC 1.4%
Value $4.334M Shares 705,881 Share Price $6.14 * Est. Cost/Share $6.22 Unrealized @ Report Date +10.5%
REPL REPLIMUNE GROUP INC 1.4%
Value $4.277M Shares 250,000 Share Price $17.11 * Est. Cost/Share $19.54 Unrealized @ Report Date +0.5%
VRDN VIRIDIAN THERAPEUTICS INC 1.4%
Value $4.218M Shares 275,000 Share Price $15.34 * Est. Cost/Share $20.10 Unrealized @ Report Date -5.1%
TSHA TAYSHA GENE THERAPIES INC 1.4%
Value $4.187M Shares 1,325,000 Share Price $3.16 * Est. Cost/Share $1.87 Unrealized @ Report Date 0.0%
— DECIPHERA PHARMACEUTICALS IN 1.4%
Value $4.134M Shares 325,000 Share Price $12.72 Est. Cost/Share $12.72 Unrealized @ Report Date —
PHAT PHATHOM PHARMACEUTICALS INC 1.3%
Value $4.096M Shares 395,000 Share Price $10.37 * Est. Cost/Share $12.86 Unrealized @ Report Date +6.6%
— REVANCE THERAPEUTICS INC 1.3%
Value $4.014M Shares 350,000 Share Price $11.47 Est. Cost/Share $26.11 Unrealized @ Report Date —
AMLX AMYLYX PHARMACEUTICALS INC 1.3%
Value $3.937M Shares 215,000 Share Price $18.31 * Est. Cost/Share $27.45 Unrealized @ Report Date -23.0%
— CYMABAY THERAPEUTICS INC 1.2%
Value $3.547M Shares 237,900 Share Price $14.91 Est. Cost/Share — Unrealized @ Report Date —
XENE XENON PHARMACEUTICALS INC 1.1%
Value $3.38M Shares 98,951 Share Price $34.16 * Est. Cost/Share $36.94 Unrealized @ Report Date +1.2%
IMVT IMMUNOVANT INC 1.1%
Value $3.263M Shares 85,000 Share Price $38.39 * Est. Cost/Share $22.60 Unrealized @ Report Date 0.0%
CRNX CRINETICS PHARMACEUTICALS IN 1.0%
Value $3.017M Shares 101,443 Share Price $29.74 * Est. Cost/Share $20.61 Unrealized @ Report Date 0.0%
SNDX SYNDAX PHARMACEUTICALS INC 1.0%
Value $2.904M Shares 200,000 Share Price $14.52 * Est. Cost/Share $21.73 Unrealized @ Report Date -12.9%
— IMMUNOGEN INC 0.9%
Value $2.777M Shares 175,000 Share Price $15.87 Est. Cost/Share $9.00 Unrealized @ Report Date —
GPCR STRUCTURE THERAPEUTICS INC 0.9%
Value $2.773M Shares 55,000 Share Price $50.42 Est. Cost/Share $50.42 Unrealized @ Report Date —
— AEROVATE THERAPEUTICS INC 0.9%
Value $2.73M Shares 201,197 Share Price $13.57 Est. Cost/Share $17.75 Unrealized @ Report Date —
— MORPHOSYS AG 0.9%
Value $2.688M Shares 400,000 Share Price $6.72 Est. Cost/Share $6.72 Unrealized @ Report Date —
CYTK CYTOKINETICS INC 0.9%
Value $2.651M Shares 90,000 Share Price $29.46 * Est. Cost/Share $33.30 Unrealized @ Report Date 0.0%
— MIRATI THERAPEUTICS INC 0.9%
Value $2.614M Shares 60,000 Share Price $43.56 Est. Cost/Share $58.72 Unrealized @ Report Date —
EYPT EYEPOINT PHARMACEUTICALS INC 0.9%
Value $2.597M Shares 325,000 Share Price $7.99 * Est. Cost/Share $10.97 Unrealized @ Report Date 0.0%
VKTX VIKING THERAPEUTICS INC 0.8%
Value $2.491M Shares 225,000 Share Price $11.07 * Est. Cost/Share $8.44 Unrealized @ Report Date +69.5%
— ASTRIA THERAPEUTICS INC 0.7%
Value $2.238M Shares 300,000 Share Price $7.46 Est. Cost/Share $9.04 Unrealized @ Report Date —
FOLD AMICUS THERAPEUTICS INC 0.7%
Value $2.128M Shares 175,000 Share Price $12.16 * Est. Cost/Share $12.33 Unrealized @ Report Date +4.7%
— KARUNA THERAPEUTICS INC 0.7%
Value $2.114M Shares 12,500 Share Price $169.09 Est. Cost/Share $144.21 Unrealized @ Report Date —
— ACELYRIN INC 0.7%
Value $2.034M Shares 200,000 Share Price $10.17 Est. Cost/Share $10.17 Unrealized @ Report Date —
— ACELYRIN INC 0.7%
Value $2.034M Shares 200,000 Share Price $10.17 Est. Cost/Share $10.17 Unrealized @ Report Date —
ZNTL ZENTALIS PHARMACEUTICALS INC 0.7%
Value $2.006M Shares 100,000 Share Price $20.06 * Est. Cost/Share $23.99 Unrealized @ Report Date +5.8%
BBIO BRIDGEBIO PHARMA INC 0.7%
Value $1.978M Shares 75,000 Share Price $26.37 * Est. Cost/Share $19.78 Unrealized @ Report Date +43.4%
ACAD ACADIA PHARMACEUTICALS INC 0.5%
Value $1.667M Shares 80,000 Share Price $20.84 * Est. Cost/Share $27.16 Unrealized @ Report Date 0.0%
LEGN LEGEND BIOTECH CORP 0.5%
Value $1.511M Shares 22,500 Share Price $67.17 Est. Cost/Share $67.17 Unrealized @ Report Date —
QURE UNIQURE NV 0.5%
Value $1.443M Shares 215,000 Share Price $6.71 * Est. Cost/Share $20.98 Unrealized @ Report Date -57.1%
RCUS ARCUS BIOSCIENCES INC 0.4%
Value $1.346M Shares 75,000 Share Price $17.95 * Est. Cost/Share $19.11 Unrealized @ Report Date +5.1%
TVTX TRAVERE THERAPEUTICS INC 0.4%
Value $1.341M Shares 150,000 Share Price $8.94 * Est. Cost/Share $14.11 Unrealized @ Report Date 0.0%
ARGX ARGENX SE 0.4%
Value $1.229M Shares 2,500 Share Price $491.63 Est. Cost/Share $491.63 Unrealized @ Report Date —
VTYX VENTYX BIOSCIENCES INC 0.4%
Value $1.216M Shares 35,000 Share Price $34.73 Est. Cost/Share $34.57 Unrealized @ Report Date 0.0%
WHWK AADI BIOSCIENCE INC 0.4%
Value $1.21M Shares 250,000 Share Price $4.84 * Est. Cost/Share $13.64 Unrealized @ Report Date -57.4%
KALV KALVISTA PHARMACEUTICALS INC 0.3%
Value $963K Shares 100,000 Share Price $9.63 * Est. Cost/Share $10.22 Unrealized @ Report Date 0.0%
BMEA BIOMEA FUSION INC 0.3%
Value $894K Shares 65,000 Share Price $13.76 * Est. Cost/Share $19.38 Unrealized @ Report Date -7.0%
ROIV ROIVANT SCIENCES LTD 0.2%
Value $748K Shares 64,000 Share Price $11.68 * Est. Cost/Share $8.94 Unrealized @ Report Date +26.4%
— VERONA PHARMA PLC 0.2%
Value $734K Shares 45,000 Share Price $16.30 Est. Cost/Share $21.14 Unrealized @ Report Date —
— INHIBRX INC 0.2%
Value $642K Shares 35,000 Share Price $18.35 Est. Cost/Share $25.96 Unrealized @ Report Date —
— FUSION PHARMACEUTICALS INC 0.2%
Value $633K Shares 243,287 Share Price $2.60 Est. Cost/Share $3.91 Unrealized @ Report Date —
ABOS ACUMEN PHARMACEUTICALS INC 0.2%
Value $623K Shares 150,000 Share Price $4.15 * Est. Cost/Share $6.18 Unrealized @ Report Date 0.0%
— 89BIO INC 0.2%
Value $463K Shares 30,000 Share Price $15.44 Est. Cost/Share $15.44 Unrealized @ Report Date —
RNAM AVIDITY BIOSCIENCES INC 0.1%
Value $415K Shares 65,000 Share Price $6.38 * Est. Cost/Share $16.33 Unrealized @ Report Date -47.2%
— RAIN ONCOLOGY INC 0.1%
Value $280K Shares 325,000 Share Price $0.86 Est. Cost/Share $7.00 Unrealized @ Report Date —
— MERSANA THERAPEUTICS INC 0.0%
Value $77,788 Shares 61,250 Share Price $1.27 Est. Cost/Share $3.29 Unrealized @ Report Date —