Ghost Tree Capital, LLC Hedge Fund

CIK: 0001595851 · Show all filings

Period: Q1 2024 (← Previous) (Next →)

Filing Date: May 15, 2024

Total Value: $361M (100.0% shares, 0.0% debt)

Holdings (72)

XBI SPDR SER TR 6.6%
Value $23.72M Shares 250,000 Share Price $94.89 Est. Cost/Share — Unrealized @ Report Date —
AXSM AXSOME THERAPEUTICS INC 4.6%
Value $16.76M Shares 210,000 Share Price $79.80 * Est. Cost/Share $54.36 Unrealized @ Report Date +54.4%
SRPT SAREPTA THERAPEUTICS INC 4.5%
Value $16.18M Shares 125,000 Share Price $129.46 * Est. Cost/Share $101.29 Unrealized @ Report Date +20.9%
BHVN BIOHAVEN LTD 4.3%
Value $15.59M Shares 285,000 Share Price $54.69 * Est. Cost/Share $31.75 Unrealized @ Report Date +56.0%
MLTX MOONLAKE IMMUNOTHERAPEUTICS 4.2%
Value $15.07M Shares 300,000 Share Price $50.23 * Est. Cost/Share $45.36 Unrealized @ Report Date +19.6%
ROIV ROIVANT SCIENCES LTD 3.8%
Value $13.7M Shares 1,300,000 Share Price $10.54 * Est. Cost/Share $10.26 Unrealized @ Report Date +5.0%
TGTX TG THERAPEUTICS INC 3.5%
Value $12.55M Shares 825,000 Share Price $15.21 * Est. Cost/Share $15.64 Unrealized @ Report Date +1.9%
VRDN VIRIDIAN THERAPEUTICS INC 3.0%
Value $10.94M Shares 625,000 Share Price $17.51 * Est. Cost/Share $19.55 Unrealized @ Report Date -0.9%
TARS TARSUS PHARMACEUTICALS INC 3.0%
Value $10.9M Shares 300,000 Share Price $36.35 * Est. Cost/Share $20.09 Unrealized @ Report Date +46.4%
CRNX CRINETICS PHARMACEUTICALS IN 2.6%
Value $9.362M Shares 200,000 Share Price $46.81 * Est. Cost/Share $33.11 Unrealized @ Report Date +18.2%
ALNY ALNYLAM PHARMACEUTICALS INC 2.5%
Value $8.967M Shares 60,000 Share Price $149.45 * Est. Cost/Share $168.43 Unrealized @ Report Date -1.0%
SLNO SOLENO THERAPEUTICS INC 2.4%
Value $8.56M Shares 200,000 Share Price $42.80 * Est. Cost/Share $35.80 Unrealized @ Report Date +26.3%
SVRA SAVARA INC 2.2%
Value $7.968M Shares 1,600,000 Share Price $4.98 * Est. Cost/Share $4.36 Unrealized @ Report Date +10.7%
APLS APELLIS PHARMACEUTICALS INC 2.1%
Value $7.641M Shares 130,000 Share Price $58.78 * Est. Cost/Share $63.75 Unrealized @ Report Date 0.0%
— PERSPECTIVE THERAPEUTICS INC 2.0%
Value $7.14M Shares 6,000,000 Share Price $1.19 Est. Cost/Share $0.98 Unrealized @ Report Date —
— BLUEPRINT MEDICINES CORP 1.9%
Value $6.902M Shares 72,761 Share Price $94.86 Est. Cost/Share $94.86 Unrealized @ Report Date —
— AEROVATE THERAPEUTICS INC 1.8%
Value $6.653M Shares 225,000 Share Price $29.57 Est. Cost/Share $18.73 Unrealized @ Report Date —
VKTX VIKING THERAPEUTICS INC 1.8%
Value $6.56M Shares 80,000 Share Price $82.00 * Est. Cost/Share $44.50 Unrealized @ Report Date 0.0%
PCVX VAXCYTE INC 1.8%
Value $6.489M Shares 95,000 Share Price $68.31 Est. Cost/Share $41.68 Unrealized @ Report Date +66.2%
CABA CABALETTA BIO INC 1.8%
Value $6.397M Shares 375,000 Share Price $17.06 * Est. Cost/Share $19.60 Unrealized @ Report Date +9.5%
VKTX VIKING THERAPEUTICS INC 1.7%
Value $5.986M Shares 73,002 Share Price $82.00 * Est. Cost/Share $44.50 Unrealized @ Report Date 0.0%
RYTM RHYTHM PHARMACEUTICALS INC 1.5%
Value $5.416M Shares 125,000 Share Price $43.33 Est. Cost/Share $43.76 Unrealized @ Report Date 0.0%
BBIO BRIDGEBIO PHARMA INC 1.5%
Value $5.411M Shares 175,000 Share Price $30.92 * Est. Cost/Share $26.78 Unrealized @ Report Date +27.0%
REPL REPLIMUNE GROUP INC 1.5%
Value $5.311M Shares 650,000 Share Price $8.17 Est. Cost/Share $10.29 Unrealized @ Report Date -20.3%
CYTK CYTOKINETICS INC 1.5%
Value $5.258M Shares 75,000 Share Price $70.11 * Est. Cost/Share $55.32 Unrealized @ Report Date +39.8%
PHAT PHATHOM PHARMACEUTICALS INC 1.4%
Value $5.151M Shares 485,000 Share Price $10.62 * Est. Cost/Share $11.96 Unrealized @ Report Date -29.0%
IMVT IMMUNOVANT INC 1.3%
Value $4.846M Shares 150,000 Share Price $32.31 * Est. Cost/Share $36.48 Unrealized @ Report Date 0.0%
ACAD ACADIA PHARMACEUTICALS INC 1.2%
Value $4.16M Shares 225,000 Share Price $18.49 * Est. Cost/Share $25.31 Unrealized @ Report Date -2.1%
INSM INSMED INC 1.1%
Value $4.069M Shares 150,000 Share Price $27.13 * Est. Cost/Share $27.99 Unrealized @ Report Date 0.0%
TNYA TENAYA THERAPEUTICS INC 1.1%
Value $4.053M Shares 775,000 Share Price $5.23 * Est. Cost/Share $4.78 Unrealized @ Report Date 0.0%
IMVT IMMUNOVANT INC 1.1%
Value $4.039M Shares 125,000 Share Price $32.31 * Est. Cost/Share $36.48 Unrealized @ Report Date 0.0%
SYRE SPYRE THERAPEUTICS INC 1.0%
Value $3.793M Shares 100,000 Share Price $37.93 * Est. Cost/Share $28.97 Unrealized @ Report Date 0.0%
ACAD ACADIA PHARMACEUTICALS INC 1.0%
Value $3.698M Shares 200,000 Share Price $18.49 * Est. Cost/Share $25.31 Unrealized @ Report Date -2.1%
SNDX SYNDAX PHARMACEUTICALS INC 1.0%
Value $3.57M Shares 150,000 Share Price $23.80 * Est. Cost/Share $22.30 Unrealized @ Report Date 0.0%
— INTRA-CELLULAR THERAPIES INC 1.0%
Value $3.46M Shares 50,000 Share Price $69.20 Est. Cost/Share — Unrealized @ Report Date —
ENGN ENGENE HOLDINGS INC 0.9%
Value $3.39M Shares 200,000 Share Price $16.95 * Est. Cost/Share $12.24 Unrealized @ Report Date 0.0%
CGON CG ONCOLOGY INC 0.9%
Value $3.292M Shares 75,000 Share Price $43.90 * Est. Cost/Share $40.84 Unrealized @ Report Date 0.0%
GPCR STRUCTURE THERAPEUTICS INC 0.9%
Value $3.215M Shares 75,000 Share Price $42.86 Est. Cost/Share $44.30 Unrealized @ Report Date —
BBOT HELIX ACQUISITION CORP II 0.9%
Value $3.12M Shares 300,000 Share Price $10.40 Est. Cost/Share $10.35 Unrealized @ Report Date 0.0%
COGT COGENT BIOSCIENCES INC 0.8%
Value $3.024M Shares 450,000 Share Price $6.72 * Est. Cost/Share $8.27 Unrealized @ Report Date -25.2%
AQST AQUESTIVE THERAPEUTICS INC 0.8%
Value $2.995M Shares 702,941 Share Price $4.26 * Est. Cost/Share $3.33 Unrealized @ Report Date 0.0%
— DECIPHERA PHARMACEUTICALS IN 0.8%
Value $2.777M Shares 176,513 Share Price $15.73 Est. Cost/Share $12.72 Unrealized @ Report Date —
TSHA TAYSHA GENE THERAPIES INC 0.8%
Value $2.727M Shares 950,000 Share Price $2.87 * Est. Cost/Share $1.91 Unrealized @ Report Date +8.9%
— RAPT THERAPEUTICS INC 0.7%
Value $2.694M Shares 300,000 Share Price $8.98 Est. Cost/Share — Unrealized @ Report Date —
GERN GERON CORP 0.7%
Value $2.64M Shares 800,000 Share Price $3.30 * Est. Cost/Share $2.23 Unrealized @ Report Date 0.0%
— MARINUS PHARMACEUTICALS INC 0.7%
Value $2.576M Shares 285,000 Share Price $9.04 Est. Cost/Share $9.91 Unrealized @ Report Date —
ALT ALTIMMUNE INC 0.7%
Value $2.545M Shares 250,000 Share Price $10.18 Est. Cost/Share $10.17 Unrealized @ Report Date 0.0%
RGNX REGENXBIO INC 0.7%
Value $2.528M Shares 120,000 Share Price $21.07 * Est. Cost/Share $17.79 Unrealized @ Report Date 0.0%
KRYS KRYSTAL BIOTECH INC 0.7%
Value $2.491M Shares 14,000 Share Price $177.93 * Est. Cost/Share $117.03 Unrealized @ Report Date +18.7%
KALV KALVISTA PHARMACEUTICALS INC 0.7%
Value $2.372M Shares 200,000 Share Price $11.86 * Est. Cost/Share $11.14 Unrealized @ Report Date +19.7%
NTRA NATERA INC 0.6%
Value $2.287M Shares 25,000 Share Price $91.46 * Est. Cost/Share $49.96 Unrealized @ Report Date +50.6%
OLMA OLEMA PHARMACEUTICALS INC 0.6%
Value $2.264M Shares 200,000 Share Price $11.32 * Est. Cost/Share $12.90 Unrealized @ Report Date 0.0%
CRBP CORBUS PHARMACEUTICALS HLDGS 0.6%
Value $2.234M Shares 56,941 Share Price $39.24 * Est. Cost/Share $24.66 Unrealized @ Report Date 0.0%
— REVANCE THERAPEUTICS INC 0.6%
Value $2.214M Shares 450,000 Share Price $4.92 Est. Cost/Share $21.62 Unrealized @ Report Date —
PTGX PROTAGONIST THERAPEUTICS INC 0.6%
Value $2.17M Shares 75,000 Share Price $28.93 * Est. Cost/Share $17.94 Unrealized @ Report Date +51.7%
EYPT EYEPOINT PHARMACEUTICALS INC 0.5%
Value $1.86M Shares 90,000 Share Price $20.67 * Est. Cost/Share $10.97 Unrealized @ Report Date +125.8%
MDGL MADRIGAL PHARMACEUTICALS INC 0.5%
Value $1.736M Shares 6,500 Share Price $267.04 * Est. Cost/Share $197.50 Unrealized @ Report Date +19.3%
ARVN ARVINAS INC 0.5%
Value $1.651M Shares 40,000 Share Price $41.28 * Est. Cost/Share $23.38 Unrealized @ Report Date +86.9%
— ASTRIA THERAPEUTICS INC 0.4%
Value $1.619M Shares 115,000 Share Price $14.07 Est. Cost/Share $8.90 Unrealized @ Report Date —
LRMR LARIMAR THERAPEUTICS INC 0.4%
Value $1.598M Shares 210,603 Share Price $7.59 * Est. Cost/Share $7.79 Unrealized @ Report Date 0.0%
CYTK CYTOKINETICS INC 0.4%
Value $1.402M Shares 20,000 Share Price $70.11 * Est. Cost/Share $55.32 Unrealized @ Report Date +39.8%
CTMX CYTOMX THERAPEUTICS INC 0.4%
Value $1.308M Shares 600,000 Share Price $2.18 * Est. Cost/Share $1.85 Unrealized @ Report Date 0.0%
— ELEVATION ONCOLOGY INC 0.4%
Value $1.282M Shares 250,000 Share Price $5.13 Est. Cost/Share $5.13 Unrealized @ Report Date —
NGNE NEUROGENE INC 0.4%
Value $1.272M Shares 25,000 Share Price $50.90 * Est. Cost/Share $33.40 Unrealized @ Report Date 0.0%
SGMT SAGIMET BIOSCIENCES INC 0.3%
Value $1.22M Shares 225,000 Share Price $5.42 * Est. Cost/Share $7.18 Unrealized @ Report Date 0.0%
ATYR ATYR PHARMA INC 0.3%
Value $1.17M Shares 600,000 Share Price $1.95 * Est. Cost/Share $1.74 Unrealized @ Report Date 0.0%
PMVP PMV PHARMACEUTICALS INC 0.3%
Value $1.147M Shares 675,000 Share Price $1.70 * Est. Cost/Share $6.13 Unrealized @ Report Date -69.5%
ARWR ARROWHEAD PHARMACEUTICALS IN 0.3%
Value $1.001M Shares 35,000 Share Price $28.60 * Est. Cost/Share $31.99 Unrealized @ Report Date 0.0%
RARE ULTRAGENYX PHARMACEUTICAL IN 0.3%
Value $934K Shares 20,000 Share Price $46.69 Est. Cost/Share $47.17 Unrealized @ Report Date 0.0%
QURE UNIQURE NV 0.2%
Value $858K Shares 165,000 Share Price $5.20 * Est. Cost/Share $20.98 Unrealized @ Report Date -72.7%
ANTX AN2 THERAPEUTICS INC 0.2%
Value $713K Shares 219,331 Share Price $3.25 * Est. Cost/Share $10.88 Unrealized @ Report Date 0.0%
NTLA INTELLIA THERAPEUTICS INC 0.2%
Value $688K Shares 25,000 Share Price $27.51 Est. Cost/Share $27.78 Unrealized @ Report Date 0.0%