Stonepine Capital Management, LLC Quant / Systematic

Location: Bend, OR

CIK: 0001440771 · Show all filings

Period: Q1 2019 (← Previous) (Next →)

Filing Date: May 14, 2019

Total Value: $174M (100.0% shares, 0.0% debt)

Holdings (30)

VNDA VANDA PHARMACEUTICALS INC 13.3%

Value $23.19M Shares 1,260,288 Share Price $18.40 * Est. Cost/Share $21.40 Unrealized @ Report Date +6.5%

— AMARIN CORP PLC -ADR 11.3%

Value $19.65M Shares 946,379 Share Price $20.76 Est. Cost/Share $3.01 Unrealized @ Report Date —

LGND LIGAND PHARMACEUTICALS 10.8%

Value $18.86M Shares 150,000 Share Price $125.71 * Est. Cost/Share $75.76 Unrealized @ Report Date 0.0%

— NEOS THERAPEUTICS INC 6.8%

Value $11.78M Shares 4,511,504 Share Price $2.61 Est. Cost/Share $1.88 Unrealized @ Report Date —

— APOLLO ENDOSURGERY INC 5.6%

Value $9.651M Shares 2,580,518 Share Price $3.74 Est. Cost/Share $4.60 Unrealized @ Report Date —

— BIODELIVERY SCIENCES INTL 4.7%

Value $8.159M Shares 1,539,437 Share Price $5.30 Est. Cost/Share $2.54 Unrealized @ Report Date —

— HTG MOLECULAR DIAGNOSTICS 4.1%

Value $7.089M Shares 2,835,786 Share Price $2.50 Est. Cost/Share $2.67 Unrealized @ Report Date —

— ADAMAS PHARMACEUTICALS INC 4.0%

Value $6.999M Shares 984,329 Share Price $7.11 Est. Cost/Share $7.11 Unrealized @ Report Date —

CPIX CUMBERLAND PHARMACEUTICALS 4.0%

Value $6.983M Shares 1,201,975 Share Price $5.81 Est. Cost/Share $5.84 Unrealized @ Report Date -0.6%

— ALIMERA SCIENCES INC 4.0%

Value $6.873M Shares 6,483,610 Share Price $1.06 Est. Cost/Share $1.18 Unrealized @ Report Date —

— AEGERION PHARMACEUTICALSAEGR 2 08/15/19 3.5%

Value $6.032M Shares 9,000,000 Share Price $0.67 Est. Cost/Share $0.67 Unrealized @ Report Date —

ENTA ENANTA PHARMACEUTICALS INC 3.3%

Value $5.811M Shares 60,840 Share Price $95.51 * Est. Cost/Share $89.70 Unrealized @ Report Date 0.0%

— OPHTHOTECH CORP 3.3%

Value $5.746M Shares 4,074,944 Share Price $1.41 Est. Cost/Share $2.69 Unrealized @ Report Date —

— CTI BIOPHARMA CORP 2.2%

Value $3.881M Shares 4,000,000 Share Price $0.97 Est. Cost/Share $3.06 Unrealized @ Report Date —

— OPIANT PHARMACEUTICALS INC 2.2%

Value $3.869M Shares 294,894 Share Price $13.12 Est. Cost/Share $16.22 Unrealized @ Report Date —

— APTEVO THERAPEUTICS INC 2.0%

Value $3.505M Shares 3,894,219 Share Price $0.90 Est. Cost/Share $0.90 Unrealized @ Report Date —

— VIVEVE MEDICAL INC 1.8%

Value $3.199M Shares 3,403,402 Share Price $0.94 Est. Cost/Share $6.92 Unrealized @ Report Date —

XOMA XOMA CORP 1.6%

Value $2.816M Shares 227,430 Share Price $12.38 * Est. Cost/Share $13.68 Unrealized @ Report Date 0.0%

— FOAMIX PHARMACEUTICALS LTD 1.6%

Value $2.738M Shares 730,004 Share Price $3.75 Est. Cost/Share $4.50 Unrealized @ Report Date —

EBS EMERGENT BIOSOLUTIONS INC 1.4%

Value $2.364M Shares 46,800 Share Price $50.51 * Est. Cost/Share $58.99 Unrealized @ Report Date 0.0%

— OXFORD IMMUNOTEC GLOBAL PLC 1.3%

Value $2.192M Shares 127,224 Share Price $17.23 Est. Cost/Share $16.23 Unrealized @ Report Date —

— MATINAS BIOPHARMA HOLDINGS I 1.3%

Value $2.189M Shares 2,008,006 Share Price $1.09 Est. Cost/Share $1.09 Unrealized @ Report Date —

— AFFIMED NV 1.2%

Value $2.124M Shares 505,736 Share Price $4.20 Est. Cost/Share $3.11 Unrealized @ Report Date —

— CHIASMA INC 0.9%

Value $1.56M Shares 300,000 Share Price $5.20 Est. Cost/Share $5.20 Unrealized @ Report Date —

— VERASTEM INC 0.9%

Value $1.48M Shares 500,000 Share Price $2.96 Est. Cost/Share $2.96 Unrealized @ Report Date —

— INTERPACE DIAGNOSTICS GROUP 0.7%

Value $1.147M Shares 1,434,030 Share Price $0.80 Est. Cost/Share $0.80 Unrealized @ Report Date —

DMAC DIAMEDICA THERAPEUTICS INC 0.7%

Value $1.135M Shares 250,000 Share Price $4.54 * Est. Cost/Share $3.61 Unrealized @ Report Date 0.0%

XENE XENON PHARMACEUTICALS INC 0.6%

Value $1.004M Shares 98,860 Share Price $10.16 * Est. Cost/Share $8.48 Unrealized @ Report Date 0.0%

— STRONGBRIDGE BIOPHARMA PLC 0.5%

Value $932K Shares 187,074 Share Price $4.98 Est. Cost/Share $4.98 Unrealized @ Report Date —

COLL COLLEGIUM PHARMACEUTICAL INC 0.5%

Value $909K Shares 60,045 Share Price $15.14 * Est. Cost/Share $16.02 Unrealized @ Report Date 0.0%

Ticker	Issuer	Shares	Value	%	Share Price	Est. Cost/Share	Unrealized @ Report Date	Class	CUSIP
VNDA	VANDA PHARMACEUTICALS INC	1,260,288	$23.19M	13.3%	$18.40 *	$21.40	+6.5%	COM	921659108
—	AMARIN CORP PLC -ADR	946,379	$19.65M	11.3%	$20.76	$3.01	—	SPONS ADR NEW	023111206
LGND	LIGAND PHARMACEUTICALS	150,000	$18.86M	10.8%	$125.71 *	$75.76	0.0%	COM NEW	53220K504
—	NEOS THERAPEUTICS INC	4,511,504	$11.78M	6.8%	$2.61	$1.88	—	COM	64052L106
—	APOLLO ENDOSURGERY INC	2,580,518	$9.651M	5.6%	$3.74	$4.60	—	COM	03767D108
—	BIODELIVERY SCIENCES INTL	1,539,437	$8.159M	4.7%	$5.30	$2.54	—	COM	09060J106
—	HTG MOLECULAR DIAGNOSTICS	2,835,786	$7.089M	4.1%	$2.50	$2.67	—	COM	40434H104
—	ADAMAS PHARMACEUTICALS INC	984,329	$6.999M	4.0%	$7.11	$7.11	—	COM	00548A106
CPIX	CUMBERLAND PHARMACEUTICALS	1,201,975	$6.983M	4.0%	$5.81	$5.84	-0.6%	COM	230770109
—	ALIMERA SCIENCES INC	6,483,610	$6.873M	4.0%	$1.06	$1.18	—	COM	016259103
—	AEGERION PHARMACEUTICALSAEGR 2 08/15/19	9,000,000	$6.032M	3.5%	$0.67	$0.67	—	NOTE 2.000% 8/1	00767EAB8
ENTA	ENANTA PHARMACEUTICALS INC	60,840	$5.811M	3.3%	$95.51 *	$89.70	0.0%	COM	29251M106
—	OPHTHOTECH CORP	4,074,944	$5.746M	3.3%	$1.41	$2.69	—	COM	683745103
—	CTI BIOPHARMA CORP	4,000,000	$3.881M	2.2%	$0.97	$3.06	—	COM NEW	12648L601
—	OPIANT PHARMACEUTICALS INC	294,894	$3.869M	2.2%	$13.12	$16.22	—	COM	683750103
—	APTEVO THERAPEUTICS INC	3,894,219	$3.505M	2.0%	$0.90	$0.90	—	COM	03835L108
—	VIVEVE MEDICAL INC	3,403,402	$3.199M	1.8%	$0.94	$6.92	—	COM NEW	92852W204
XOMA	XOMA CORP	227,430	$2.816M	1.6%	$12.38 *	$13.68	0.0%	COM NEW	98419J206
—	FOAMIX PHARMACEUTICALS LTD	730,004	$2.738M	1.6%	$3.75	$4.50	—	SHS	M46135105
EBS	EMERGENT BIOSOLUTIONS INC	46,800	$2.364M	1.4%	$50.51 *	$58.99	0.0%	COM	29089Q105
—	OXFORD IMMUNOTEC GLOBAL PLC	127,224	$2.192M	1.3%	$17.23	$16.23	—	ORD SHS	G6855A103
—	MATINAS BIOPHARMA HOLDINGS I	2,008,006	$2.189M	1.3%	$1.09	$1.09	—	COM	576810105
—	AFFIMED NV	505,736	$2.124M	1.2%	$4.20	$3.11	—	COM	N01045108
—	CHIASMA INC	300,000	$1.56M	0.9%	$5.20	$5.20	—	COM	16706W102
—	VERASTEM INC	500,000	$1.48M	0.9%	$2.96	$2.96	—	COM	92337C104
—	INTERPACE DIAGNOSTICS GROUP	1,434,030	$1.147M	0.7%	$0.80	$0.80	—	COM NEW	46062X204
DMAC	DIAMEDICA THERAPEUTICS INC	250,000	$1.135M	0.7%	$4.54 *	$3.61	0.0%	COM NEW	25253X207
XENE	XENON PHARMACEUTICALS INC	98,860	$1.004M	0.6%	$10.16 *	$8.48	0.0%	COM	98420N105
—	STRONGBRIDGE BIOPHARMA PLC	187,074	$932K	0.5%	$4.98	$4.98	—	SHS USD	G85347105
COLL	COLLEGIUM PHARMACEUTICAL INC	60,045	$909K	0.5%	$15.14 *	$16.02	0.0%	COM	19459J104