Stonepine Capital Management, LLC Quant / Systematic

Location: Bend, OR

CIK: 0001440771 · Show all filings

Period: Q3 2021 (← Previous) (Next →)

Filing Date: Nov 12, 2021

Total Value: $220M (100.0% shares, 0.0% debt)

Holdings (31)

— AMRYT PHARMA PLC - SPNR ADR 31.8%

Value $69.88M Shares 5,801,748 Share Price $12.04 Est. Cost/Share $12.69 Unrealized @ Report Date —

— CTI BIOPHARMA CORP 10.7%

Value $23.5M Shares 7,964,329 Share Price $2.95 Est. Cost/Share $2.50 Unrealized @ Report Date —

— ADAMAS PHARMACEUTICALS INC 8.7%

Value $19.22M Shares 3,914,938 Share Price $4.91 Est. Cost/Share $4.82 Unrealized @ Report Date —

GLPG GALAPAGOS NV-SPON ADR 5.8%

Value $12.85M Shares 244,205 Share Price $52.61 Est. Cost/Share $52.61 Unrealized @ Report Date —

OVID OVID THERAPEUTICS INC 5.0%

Value $10.93M Shares 3,252,892 Share Price $3.36 * Est. Cost/Share $3.45 Unrealized @ Report Date +5.8%

— CATALYST BIOSCIENCES INC 4.9%

Value $10.83M Shares 2,635,014 Share Price $4.11 Est. Cost/Share $4.78 Unrealized @ Report Date —

— STRONGBRIDGE BIOPHARMA PLC 4.2%

Value $9.159M Shares 4,489,687 Share Price $2.04 Est. Cost/Share $2.64 Unrealized @ Report Date —

— APOLLO ENDOSURGERY INC 3.8%

Value $8.264M Shares 912,125 Share Price $9.06 Est. Cost/Share $4.82 Unrealized @ Report Date —

— AFFIMED NV 3.3%

Value $7.178M Shares 1,161,466 Share Price $6.18 Est. Cost/Share $6.74 Unrealized @ Report Date —

— GAMIDA CELL LTD 3.1%

Value $6.759M Shares 1,724,201 Share Price $3.92 Est. Cost/Share $4.84 Unrealized @ Report Date —

XGN EXAGEN INC 2.4%

Value $5.313M Shares 390,637 Share Price $13.60 * Est. Cost/Share $15.26 Unrealized @ Report Date -12.9%

CELC CELCUITY INC 2.4%

Value $5.304M Shares 294,692 Share Price $18.00 * Est. Cost/Share $20.31 Unrealized @ Report Date +4.4%

— YUMANITY THERAPEUTICS INC 2.3%

Value $4.971M Shares 481,692 Share Price $10.32 Est. Cost/Share $15.79 Unrealized @ Report Date —

ATYR ATYR PHARMA INC 1.7%

Value $3.728M Shares 410,535 Share Price $9.08 * Est. Cost/Share $5.98 Unrealized @ Report Date 0.0%

KALV KALVISTA PHARMACEUTICALS INC 1.6%

Value $3.49M Shares 200,000 Share Price $17.45 * Est. Cost/Share $26.28 Unrealized @ Report Date -22.9%

— SYNLOGIC INC 1.4%

Value $3.05M Shares 1,000,000 Share Price $3.05 Est. Cost/Share $3.05 Unrealized @ Report Date —

— ANGION BIOMEDICA CORP 1.2%

Value $2.737M Shares 280,183 Share Price $9.77 Est. Cost/Share $14.79 Unrealized @ Report Date —

EOLS EVOLUS INC 1.0%

Value $2.286M Shares 300,000 Share Price $7.62 * Est. Cost/Share $10.34 Unrealized @ Report Date 0.0%

— AVALO THERAPEUTICS INC 0.8%

Value $1.853M Shares 850,000 Share Price $2.18 Est. Cost/Share $2.18 Unrealized @ Report Date —

— CIDARA THERAPEUTICS INC 0.8%

Value $1.754M Shares 782,817 Share Price $2.24 Est. Cost/Share $2.02 Unrealized @ Report Date —

XOMA XOMA CORP 0.8%

Value $1.696M Shares 68,542 Share Price $24.74 * Est. Cost/Share $20.24 Unrealized @ Report Date +45.5%

— LEAP THERAPEUTICS INC 0.5%

Value $1.003M Shares 250,000 Share Price $4.01 Est. Cost/Share $4.01 Unrealized @ Report Date —

— ANTARES PHARMA INC 0.4%

Value $961K Shares 264,100 Share Price $3.64 Est. Cost/Share $3.64 Unrealized @ Report Date —

EYPT EYEPOINT PHARMACEUTICALS INC 0.4%

Value $839K Shares 80,537 Share Price $10.42 * Est. Cost/Share $11.25 Unrealized @ Report Date -15.2%

DMAC DIAMEDICA THERAPEUTICS INC 0.3%

Value $665K Shares 165,775 Share Price $4.01 * Est. Cost/Share $4.96 Unrealized @ Report Date -22.8%

— CONFORMIS INC 0.3%

Value $648K Shares 486,982 Share Price $1.33 Est. Cost/Share $1.04 Unrealized @ Report Date —

— NEUBASE THERAPEUTICS INC 0.2%

Value $396K Shares 109,742 Share Price $3.61 Est. Cost/Share $3.94 Unrealized @ Report Date —

IMUX IMMUNIC INC 0.1%

Value $198K Shares 22,409 Share Price $8.84 * Est. Cost/Share $9.84 Unrealized @ Report Date 0.0%

— CONTRAFECT CORP 0.1%

Value $139K Shares 34,413 Share Price $4.04 Est. Cost/Share $4.80 Unrealized @ Report Date —

— SEASPINE HOLDINGS CORP 0.1%

Value $131K Shares 8,349 Share Price $15.69 Est. Cost/Share $15.69 Unrealized @ Report Date —

SCYX SCYNEXIS INC 0.0%

Value $34,000 Shares 6,327 Share Price $5.37 * Est. Cost/Share $6.57 Unrealized @ Report Date -0.3%

Ticker	Issuer	Shares	Value	%	Share Price	Est. Cost/Share	Unrealized @ Report Date	Class	CUSIP
—	AMRYT PHARMA PLC - SPNR ADR	5,801,748	$69.88M	31.8%	$12.04	$12.69	—	SPONSORED ADS	03217L106
—	CTI BIOPHARMA CORP	7,964,329	$23.5M	10.7%	$2.95	$2.50	—	COM	12648L601
—	ADAMAS PHARMACEUTICALS INC	3,914,938	$19.22M	8.7%	$4.91	$4.82	—	COM	00548A106
GLPG	GALAPAGOS NV-SPON ADR	244,205	$12.85M	5.8%	$52.61	$52.61	—	SPONS ADR	36315X101
OVID	OVID THERAPEUTICS INC	3,252,892	$10.93M	5.0%	$3.36 *	$3.45	+5.8%	COM	690469101
—	CATALYST BIOSCIENCES INC	2,635,014	$10.83M	4.9%	$4.11	$4.78	—	COM NEW	14888D208
—	STRONGBRIDGE BIOPHARMA PLC	4,489,687	$9.159M	4.2%	$2.04	$2.64	—	SHS USD	G85347105
—	APOLLO ENDOSURGERY INC	912,125	$8.264M	3.8%	$9.06	$4.82	—	COM	03767D108
—	AFFIMED NV	1,161,466	$7.178M	3.3%	$6.18	$6.74	—	COM	N01045108
—	GAMIDA CELL LTD	1,724,201	$6.759M	3.1%	$3.92	$4.84	—	SHS	M47364100
XGN	EXAGEN INC	390,637	$5.313M	2.4%	$13.60 *	$15.26	-12.9%	COM	30068X103
CELC	CELCUITY INC	294,692	$5.304M	2.4%	$18.00 *	$20.31	+4.4%	COM	15102K100
—	YUMANITY THERAPEUTICS INC	481,692	$4.971M	2.3%	$10.32	$15.79	—	COM	98872L102
ATYR	ATYR PHARMA INC	410,535	$3.728M	1.7%	$9.08 *	$5.98	0.0%	COM NEW	002120202
KALV	KALVISTA PHARMACEUTICALS INC	200,000	$3.49M	1.6%	$17.45 *	$26.28	-22.9%	COM	483497103
—	SYNLOGIC INC	1,000,000	$3.05M	1.4%	$3.05	$3.05	—	COM	87166L100
—	ANGION BIOMEDICA CORP	280,183	$2.737M	1.2%	$9.77	$14.79	—	COM	03476J107
EOLS	EVOLUS INC	300,000	$2.286M	1.0%	$7.62 *	$10.34	0.0%	COM	30052C107
—	AVALO THERAPEUTICS INC	850,000	$1.853M	0.8%	$2.18	$2.18	—	COM	05338F108
—	CIDARA THERAPEUTICS INC	782,817	$1.754M	0.8%	$2.24	$2.02	—	COM	171757107
XOMA	XOMA CORP	68,542	$1.696M	0.8%	$24.74 *	$20.24	+45.5%	COM NEW	98419J206
—	LEAP THERAPEUTICS INC	250,000	$1.003M	0.5%	$4.01	$4.01	—	COM	52187K101
—	ANTARES PHARMA INC	264,100	$961K	0.4%	$3.64	$3.64	—	COM	036642106
EYPT	EYEPOINT PHARMACEUTICALS INC	80,537	$839K	0.4%	$10.42 *	$11.25	-15.2%	COM NEW	30233G209
DMAC	DIAMEDICA THERAPEUTICS INC	165,775	$665K	0.3%	$4.01 *	$4.96	-22.8%	COM NEW	25253X207
—	CONFORMIS INC	486,982	$648K	0.3%	$1.33	$1.04	—	COM	20717E101
—	NEUBASE THERAPEUTICS INC	109,742	$396K	0.2%	$3.61	$3.94	—	COM	64132K102
IMUX	IMMUNIC INC	22,409	$198K	0.1%	$8.84 *	$9.84	0.0%	COM	4525EP101
—	CONTRAFECT CORP	34,413	$139K	0.1%	$4.04	$4.80	—	COM NEW	212326300
—	SEASPINE HOLDINGS CORP	8,349	$131K	0.1%	$15.69	$15.69	—	COM	81255T108
SCYX	SCYNEXIS INC	6,327	$34,000	0.0%	$5.37 *	$6.57	-0.3%	COM NEW	811292200