Stonepine Capital Management, LLC Quant / Systematic

CIK: 0001440771 · Show all filings

Period: Q3 2021 (← Previous) (Next →)

Filing Date: Nov 12, 2021

Total Value ($000): $219,763 (100.0% shares, 0.0% debt)

Holdings (31)

— AMRYT PHARMA PLC - SPNR ADR 31.8%

Value ($000) $69,882 Shares 5,801,748 Est. Cost $12.69 Unrealized —

— CTI BIOPHARMA CORP 10.7%

Value ($000) $23,495 Shares 7,964,329 Est. Cost $2.50 Unrealized —

— ADAMAS PHARMACEUTICALS INC 8.7%

Value ($000) $19,222 Shares 3,914,938 Est. Cost $4.82 Unrealized —

GLPG GALAPAGOS NV-SPON ADR 5.8%

Value ($000) $12,848 Shares 244,205 Est. Cost $52.61 Unrealized —

OVID OVID THERAPEUTICS INC 5.0%

Value ($000) $10,930 Shares 3,252,892 Est. Cost $3.45 Unrealized +5.8%

— CATALYST BIOSCIENCES INC 4.9%

Value ($000) $10,830 Shares 2,635,014 Est. Cost $4.78 Unrealized —

— STRONGBRIDGE BIOPHARMA PLC 4.2%

Value ($000) $9,159 Shares 4,489,687 Est. Cost $2.64 Unrealized —

— APOLLO ENDOSURGERY INC 3.8%

Value ($000) $8,264 Shares 912,125 Est. Cost $4.82 Unrealized —

— AFFIMED NV 3.3%

Value ($000) $7,178 Shares 1,161,466 Est. Cost $6.74 Unrealized —

— GAMIDA CELL LTD 3.1%

Value ($000) $6,759 Shares 1,724,201 Est. Cost $4.84 Unrealized —

XGN EXAGEN INC 2.4%

Value ($000) $5,313 Shares 390,637 Est. Cost $15.26 Unrealized -12.9%

CELC CELCUITY INC 2.4%

Value ($000) $5,304 Shares 294,692 Est. Cost $20.31 Unrealized +4.4%

— YUMANITY THERAPEUTICS INC 2.3%

Value ($000) $4,971 Shares 481,692 Est. Cost $15.79 Unrealized —

ATYR ATYR PHARMA INC 1.7%

Value ($000) $3,728 Shares 410,535 Est. Cost $5.98 Unrealized 0.0%

KALV KALVISTA PHARMACEUTICALS INC 1.6%

Value ($000) $3,490 Shares 200,000 Est. Cost $26.28 Unrealized -22.9%

— SYNLOGIC INC 1.4%

Value ($000) $3,050 Shares 1,000,000 Est. Cost $3.05 Unrealized —

— ANGION BIOMEDICA CORP 1.2%

Value ($000) $2,737 Shares 280,183 Est. Cost $14.79 Unrealized —

EOLS EVOLUS INC 1.0%

Value ($000) $2,286 Shares 300,000 Est. Cost $10.34 Unrealized 0.0%

— AVALO THERAPEUTICS INC 0.8%

Value ($000) $1,853 Shares 850,000 Est. Cost $2.18 Unrealized —

— CIDARA THERAPEUTICS INC 0.8%

Value ($000) $1,754 Shares 782,817 Est. Cost $2.02 Unrealized —

XOMA XOMA CORP 0.8%

Value ($000) $1,696 Shares 68,542 Est. Cost $20.24 Unrealized +45.5%

— LEAP THERAPEUTICS INC 0.5%

Value ($000) $1,003 Shares 250,000 Est. Cost $4.01 Unrealized —

— ANTARES PHARMA INC 0.4%

Value ($000) $961 Shares 264,100 Est. Cost $3.64 Unrealized —

EYPT EYEPOINT PHARMACEUTICALS INC 0.4%

Value ($000) $839 Shares 80,537 Est. Cost $11.25 Unrealized -15.2%

DMAC DIAMEDICA THERAPEUTICS INC 0.3%

Value ($000) $665 Shares 165,775 Est. Cost $4.96 Unrealized -22.8%

— CONFORMIS INC 0.3%

Value ($000) $648 Shares 486,982 Est. Cost $1.04 Unrealized —

— NEUBASE THERAPEUTICS INC 0.2%

Value ($000) $396 Shares 109,742 Est. Cost $3.94 Unrealized —

IMUX IMMUNIC INC 0.1%

Value ($000) $198 Shares 22,409 Est. Cost $9.84 Unrealized 0.0%

— CONTRAFECT CORP 0.1%

Value ($000) $139 Shares 34,413 Est. Cost $4.80 Unrealized —

— SEASPINE HOLDINGS CORP 0.1%

Value ($000) $131 Shares 8,349 Est. Cost $15.69 Unrealized —

SCYX SCYNEXIS INC 0.0%

Value ($000) $34 Shares 6,327 Est. Cost $6.57 Unrealized -0.3%

Ticker	Issuer	Shares	Value ($000)	%	Est. Cost	Unrealized	Class	CUSIP
—	AMRYT PHARMA PLC - SPNR ADR	5,801,748	$69,882	31.8%	$12.69	—	SPONSORED ADS	03217L106
—	CTI BIOPHARMA CORP	7,964,329	$23,495	10.7%	$2.50	—	COM	12648L601
—	ADAMAS PHARMACEUTICALS INC	3,914,938	$19,222	8.7%	$4.82	—	COM	00548A106
GLPG	GALAPAGOS NV-SPON ADR	244,205	$12,848	5.8%	$52.61	—	SPONS ADR	36315X101
OVID	OVID THERAPEUTICS INC	3,252,892	$10,930	5.0%	$3.45	+5.8%	COM	690469101
—	CATALYST BIOSCIENCES INC	2,635,014	$10,830	4.9%	$4.78	—	COM NEW	14888D208
—	STRONGBRIDGE BIOPHARMA PLC	4,489,687	$9,159	4.2%	$2.64	—	SHS USD	G85347105
—	APOLLO ENDOSURGERY INC	912,125	$8,264	3.8%	$4.82	—	COM	03767D108
—	AFFIMED NV	1,161,466	$7,178	3.3%	$6.74	—	COM	N01045108
—	GAMIDA CELL LTD	1,724,201	$6,759	3.1%	$4.84	—	SHS	M47364100
XGN	EXAGEN INC	390,637	$5,313	2.4%	$15.26	-12.9%	COM	30068X103
CELC	CELCUITY INC	294,692	$5,304	2.4%	$20.31	+4.4%	COM	15102K100
—	YUMANITY THERAPEUTICS INC	481,692	$4,971	2.3%	$15.79	—	COM	98872L102
ATYR	ATYR PHARMA INC	410,535	$3,728	1.7%	$5.98	0.0%	COM NEW	002120202
KALV	KALVISTA PHARMACEUTICALS INC	200,000	$3,490	1.6%	$26.28	-22.9%	COM	483497103
—	SYNLOGIC INC	1,000,000	$3,050	1.4%	$3.05	—	COM	87166L100
—	ANGION BIOMEDICA CORP	280,183	$2,737	1.2%	$14.79	—	COM	03476J107
EOLS	EVOLUS INC	300,000	$2,286	1.0%	$10.34	0.0%	COM	30052C107
—	AVALO THERAPEUTICS INC	850,000	$1,853	0.8%	$2.18	—	COM	05338F108
—	CIDARA THERAPEUTICS INC	782,817	$1,754	0.8%	$2.02	—	COM	171757107
XOMA	XOMA CORP	68,542	$1,696	0.8%	$20.24	+45.5%	COM NEW	98419J206
—	LEAP THERAPEUTICS INC	250,000	$1,003	0.5%	$4.01	—	COM	52187K101
—	ANTARES PHARMA INC	264,100	$961	0.4%	$3.64	—	COM	036642106
EYPT	EYEPOINT PHARMACEUTICALS INC	80,537	$839	0.4%	$11.25	-15.2%	COM NEW	30233G209
DMAC	DIAMEDICA THERAPEUTICS INC	165,775	$665	0.3%	$4.96	-22.8%	COM NEW	25253X207
—	CONFORMIS INC	486,982	$648	0.3%	$1.04	—	COM	20717E101
—	NEUBASE THERAPEUTICS INC	109,742	$396	0.2%	$3.94	—	COM	64132K102
IMUX	IMMUNIC INC	22,409	$198	0.1%	$9.84	0.0%	COM	4525EP101
—	CONTRAFECT CORP	34,413	$139	0.1%	$4.80	—	COM NEW	212326300
—	SEASPINE HOLDINGS CORP	8,349	$131	0.1%	$15.69	—	COM	81255T108
SCYX	SCYNEXIS INC	6,327	$34	0.0%	$6.57	-0.3%	COM NEW	811292200