Location: Greenwich, CT
CIK: 0001856083 · Show all filings
Period: Q1 2023 (← Previous) (Next →)
Filing Date: May 15, 2023
Total Value: $2.435B (100.0% shares, 0.0% debt)
| Ticker | Issuer | Shares | Value | % | Est. Cost | Unrealized | Class | CUSIP |
|---|---|---|---|---|---|---|---|---|
| JAZZ | JAZZ PHARMACEUTICALS PLC | 1,200,000 | $176M | 7.2% | $142.46 | +3.8% | SHS USD | G50871105 |
| — | IVERIC BIO INC | 6,500,000 | $158M | 6.5% | $17.64 | — | COM | 46583P102 |
| TVTX | TRAVERE THERAPEUTICS INC | 6,147,268 | $138M | 5.7% | $25.19 | -15.6% | COM | 89422G107 |
| IMVT | IMMUNOVANT INC | 7,432,717 | $115M | 4.7% | $6.72 | +158.1% | COM | 45258J102 |
| INSM | INSMED INC | 6,500,000 | $111M | 4.6% | $19.36 | +0.3% | COM PAR $.01 | 457669307 |
| IONS | IONIS PHARMACEUTICALS INC | 2,834,069 | $101M | 4.2% | $39.47 | -4.9% | COM | 462222100 |
| — | INTRA-CELLULAR THERAPIES INC | 1,700,000 | $92.06M | 3.8% | $54.15 | — | COM | 46116X101 |
| PLRX | PLIANT THERAPEUTICS INC | 3,422,057 | $91.03M | 3.7% | $23.91 | +19.1% | COM | 729139105 |
| ALKS | ALKERMES PLC | 3,000,000 | $84.57M | 3.5% | $27.24 | 0.0% | SHS | G01767105 |
| — | SPRINGWORKS THERAPEUTICS INC | 3,100,000 | $79.79M | 3.3% | $27.93 | — | COM | 85205L107 |
| — | CHINOOK THERAPEUTICS INC | 3,000,000 | $69.45M | 2.9% | $16.47 | — | COM | 16961L106 |
| — | REATA PHARMACEUTICALS INC | 729,000 | $66.28M | 2.7% | $90.92 | — | CL A | 75615P103 |
| — | VERONA PHARMA PLC | 3,187,415 | $64M | 2.6% | $12.01 | — | SPONSORED ADS | 925050106 |
| GPCR | STRUCTURE THERAPEUTICS INC | 2,646,782 | $62.97M | 2.6% | $23.79 | — | SPONSORED ADS | 86366E106 |
| — | DYNAVAX TECHNOLOGIES CORP | 6,350,000 | $62.29M | 2.6% | $10.11 | — | COM NEW | 268158201 |
| BCYC | BICYCLE THERAPEUTICS PLC | 2,819,045 | $59.96M | 2.5% | $40.57 | — | SPONSORED ADS | 088786108 |
| GERN | GERON CORP | 26,867,479 | $58.3M | 2.4% | $2.67 | +6.2% | COM | 374163103 |
| BIIB | BIOGEN INC | 200,000 | $55.61M | 2.3% | $282.44 | -2.0% | COM | 09062X103 |
| — | DICE THERAPEUTICS INC | 1,600,000 | $45.84M | 1.9% | $27.80 | — | COM | 23345J104 |
| — | AGENUS INC | 30,000,000 | $45.6M | 1.9% | $2.17 | — | COM NEW | 00847G705 |
| — | SEAGEN INC | 217,800 | $44.1M | 1.8% | — | — | Put | 81181C104 |
| PACB | PACIFIC BIOSCIENCES CALIF IN | 3,504,390 | $40.58M | 1.7% | $9.94 | 0.0% | COM | 69404D108 |
| FDMT | 4D MOLECULAR THERAPEUTICS IN | 2,278,107 | $39.16M | 1.6% | $19.53 | -0.4% | COM | 35104E100 |
| BEAM | BEAM THERAPEUTICS INC | 1,250,000 | $38.27M | 1.6% | $62.01 | -36.4% | COM | 07373V105 |
| EXEL | EXELIXIS INC | 1,931,874 | $37.5M | 1.5% | $17.42 | 0.0% | COM | 30161Q104 |
| ARGX | ARGENX SE | 100,000 | $37.26M | 1.5% | — | — | Put | 04016X101 |
| VRDN | VIRIDIAN THERAPEUTICS INC | 1,230,259 | $31.3M | 1.3% | $18.36 | +74.6% | COM | 92790C104 |
| AUTL | AUTOLUS THERAPEUTICS PLC | 15,000,000 | $27.6M | 1.1% | $1.90 | — | SPON ADS | 05280R100 |
| — | 89BIO INC | 1,800,000 | $27.41M | 1.1% | $7.98 | — | COM | 282559103 |
| DYN | DYNE THERAPEUTICS INC | 2,334,633 | $26.89M | 1.1% | $12.14 | +7.0% | COM | 26818M108 |
| — | REPARE THERAPEUTICS INC | 2,727,606 | $26.84M | 1.1% | $18.55 | — | COM | 760273102 |
| NRIX | NURIX THERAPEUTICS INC | 2,997,830 | $26.62M | 1.1% | $11.16 | -6.6% | COM | 67080M103 |
| NTLA | INTELLIA THERAPEUTICS INC | 704,533 | $26.26M | 1.1% | $53.76 | -27.0% | COM | 45826J105 |
| — | ASTRIA THERAPEUTICS INC | 1,816,531 | $24.16M | 1.0% | $14.89 | — | COM | 04635X102 |
| — | DECIPHERA PHARMACEUTICALS IN | 1,363,201 | $21.06M | 0.9% | $15.45 | — | COM | 24344T101 |
| EWTX | EDGEWISE THERAPEUTICS INC | 3,068,259 | $20.47M | 0.8% | $10.10 | -8.3% | COM | 28036F105 |
| — | VIGIL NEUROSCIENCE INC | 2,025,137 | $19.83M | 0.8% | $8.83 | — | COM | 92673K108 |
| — | INOZYME PHARMA INC | 3,250,000 | $18.62M | 0.8% | $4.77 | — | COM | 45790W108 |
| QURE | UNIQURE NV | 865,767 | $17.44M | 0.7% | $20.98 | 0.0% | SHS | N90064101 |
| — | POINT BIOPHARMA GLOBAL INC | 2,345,073 | $17.05M | 0.7% | $7.27 | — | COM | 730541109 |
| ABOS | ACUMEN PHARMACEUTICALS INC | 3,952,000 | $16.05M | 0.7% | $8.05 | -35.1% | COM | 00509G209 |
| — | ALLAKOS INC | 3,585,000 | $15.95M | 0.7% | $6.30 | — | COM | 01671P100 |
| ACRS | ACLARIS THERAPEUTICS INC | 1,708,971 | $13.83M | 0.6% | $12.69 | 0.0% | COM | 00461U105 |
| NUVB | NUVATION BIO INC | 7,720,688 | $12.82M | 0.5% | $4.49 | -54.8% | COM CL A | 67080N101 |
| SLN | SILENCE THERAPEUTICS PLC | 1,951,580 | $12.1M | 0.5% | $16.79 | — | ADS | 82686Q101 |
| — | RAPT THERAPEUTICS INC | 571,233 | $10.48M | 0.4% | $19.80 | — | COM | 75382E109 |
| — | JOUNCE THERAPEUTICS INC | 4,259,653 | $7.88M | 0.3% | $8.25 | — | COM | 481116101 |
| RLMD | RELMADA THERAPEUTICS INC | 2,837,818 | $6.413M | 0.3% | $10.86 | -68.3% | COM | 75955J402 |
| — | ORCHARD THERAPEUTICS PLC | 1,166,670 | $6.265M | 0.3% | $5.37 | — | SPON ADS NEW | 68570P200 |
| HRTX | HERON THERAPEUTICS INC | 3,234,722 | $4.884M | 0.2% | $3.91 | -36.0% | COM | 427746102 |
| NKTX | NKARTA INC | 1,354,200 | $4.807M | 0.2% | $14.20 | -66.6% | COM | 65487U108 |
| GHRS | GH RESEARCH PLC | 499,400 | $3.99M | 0.2% | $21.97 | -58.2% | ORDINARY SHARES | G3855L106 |
| IMUX | IMMUNIC INC | 2,524,242 | $3.761M | 0.2% | $1.86 | 0.0% | COM | 4525EP101 |
| — | 2SEVENTY BIO INC | 350,000 | $3.57M | 0.1% | $10.20 | — | COMMON STOCK | 901384107 |
| IPSC | CENTURY THERAPEUTICS INC | 1,022,892 | $3.549M | 0.1% | $11.43 | -61.6% | COM | 15673T100 |
| — | IMMUNOGEN INC | 428,100 | $1.644M | 0.1% | — | — | Put | 45253H101 |
| — | NEKTAR THERAPEUTICS | 1,743,248 | $1.225M | 0.1% | $0.70 | — | COM | 640268108 |
| — | 89BIO INC | 4,400 | $67,012 | 0.0% | $7.98 | — | Put | 282559103 |