Location: Greenwich, CT
CIK: 0001856083 · Show all filings
Period: Q3 2023 (← Previous) (Next →)
Filing Date: Nov 14, 2023
Total Value: $2.591B (100.0% shares, 0.0% debt)
| Ticker | Issuer | Shares | Value | % | Est. Cost | Unrealized | Class | CUSIP |
|---|---|---|---|---|---|---|---|---|
| INSM | INSMED INC | 6,000,000 | $152M | 5.8% | $19.36 | +18.1% | COM PAR $.01 | 457669307 |
| JAZZ | JAZZ PHARMACEUTICALS PLC | 1,138,045 | $147M | 5.7% | $142.14 | -6.3% | SHS USD | G50871105 |
| — | INTRA-CELLULAR THERAPIES INC | 2,600,000 | $135M | 5.2% | $53.32 | — | COM | 46116X101 |
| IONS | IONIS PHARMACEUTICALS INC | 2,834,069 | $129M | 5.0% | $39.47 | +4.5% | COM | 462222100 |
| GH | GUARDANT HEALTH INC | 4,050,000 | $120M | 4.6% | $32.78 | +7.3% | COM | 40131M109 |
| IMVT | IMMUNOVANT INC | 2,797,955 | $107M | 4.1% | $6.72 | +236.2% | COM | 45258J102 |
| ALKS | ALKERMES PLC | 3,800,000 | $106M | 4.1% | $27.68 | +5.9% | SHS | G01767105 |
| — | DYNAVAX TECHNOLOGIES CORP | 6,756,956 | $99.8M | 3.9% | $10.34 | — | COM NEW | 268158201 |
| GPCR | STRUCTURE THERAPEUTICS INC | 1,915,000 | $96.55M | 3.7% | $23.79 | — | SPONSORED ADS | 86366E106 |
| PLRX | PLIANT THERAPEUTICS INC | 5,500,000 | $95.37M | 3.7% | $22.15 | -21.7% | COM | 729139105 |
| — | SPRINGWORKS THERAPEUTICS INC | 3,546,435 | $81.99M | 3.2% | $27.71 | — | COM | 85205L107 |
| AXSM | AXSOME THERAPEUTICS INC | 1,140,745 | $79.73M | 3.1% | $74.42 | +0.4% | COM | 05464T104 |
| BCYC | BICYCLE THERAPEUTICS PLC | 3,490,506 | $70.12M | 2.7% | $36.63 | — | SPONSORED ADS | 088786108 |
| TVTX | TRAVERE THERAPEUTICS INC | 7,370,000 | $65.89M | 2.5% | $24.03 | -41.3% | COM | 89422G107 |
| NTLA | INTELLIA THERAPEUTICS INC | 2,000,000 | $63.24M | 2.4% | $44.18 | -12.2% | COM | 45826J105 |
| EDIT | EDITAS MEDICINE INC | 7,101,935 | $55.4M | 2.1% | $8.64 | -0.8% | COM | 28106W103 |
| GERN | GERON CORP | 25,700,000 | $54.48M | 2.1% | $2.68 | +1.4% | COM | 374163103 |
| — | VERONA PHARMA PLC | 3,187,415 | $51.95M | 2.0% | $12.01 | — | SPONSORED ADS | 925050106 |
| APGE | APOGEE THERAPEUTICS INC | 2,414,373 | $51.43M | 2.0% | $22.03 | 0.0% | COM | 03770N101 |
| PACB | PACIFIC BIOSCIENCES CALIF IN | 6,000,000 | $50.1M | 1.9% | $11.07 | +3.2% | COM | 69404D108 |
| VRDN | VIRIDIAN THERAPEUTICS INC | 2,963,267 | $45.46M | 1.8% | $18.89 | +1.0% | COM | 92790C104 |
| NVCR | NOVOCURE LTD | 2,500,000 | $40.38M | 1.6% | $28.83 | 0.0% | ORD SHS | G6674U108 |
| — | HILLEVAX INC | 2,900,000 | $39.01M | 1.5% | $13.45 | — | COM | 43157M102 |
| — | REPARE THERAPEUTICS INC | 3,067,731 | $37.06M | 1.4% | $17.83 | — | COM | 760273102 |
| — | AGENUS INC | 31,697,539 | $35.82M | 1.4% | $2.11 | — | COM NEW | 00847G705 |
| FDMT | 4D MOLECULAR THERAPEUTICS IN | 2,778,107 | $35.37M | 1.4% | $19.33 | -13.5% | COM | 35104E100 |
| AUTL | AUTOLUS THERAPEUTICS PLC | 15,000,000 | $34.95M | 1.3% | $1.90 | — | SPON ADS | 05280R100 |
| NBIX | NEUROCRINE BIOSCIENCES INC | 300,000 | $33.75M | 1.3% | $105.30 | 0.0% | COM | 64125C109 |
| TERN | TERNS PHARMACEUTICALS INC | 6,000,000 | $30.18M | 1.2% | $7.32 | -13.3% | COM | 880881107 |
| — | RAPT THERAPEUTICS INC | 1,500,000 | $24.93M | 1.0% | $18.43 | — | COM | 75382E109 |
| BEAM | BEAM THERAPEUTICS INC | 1,015,641 | $24.43M | 0.9% | $60.50 | -55.7% | COM | 07373V105 |
| ANAB | ANAPTYSBIO INC | 1,345,813 | $24.17M | 0.9% | $19.08 | 0.0% | COM | 032724106 |
| OLMA | OLEMA PHARMACEUTICALS INC | 1,930,894 | $23.85M | 0.9% | $10.19 | 0.0% | COM | 68062P106 |
| NRIX | NURIX THERAPEUTICS INC | 2,997,830 | $23.56M | 0.9% | $11.16 | -18.2% | COM | 67080M103 |
| ANIP | ANI PHARMACEUTICALS INC | 400,000 | $23.22M | 0.9% | $44.33 | +30.2% | COM | 00182C103 |
| AMLX | AMYLYX PHARMACEUTICALS INC | 1,259,335 | $23.06M | 0.9% | $21.15 | 0.0% | COM | 03237H101 |
| BNTX | BIONTECH SE | 200,000 | $21.73M | 0.8% | $108.64 | — | SPONSORED ADS | 09075V102 |
| DYN | DYNE THERAPEUTICS INC | 2,403,672 | $21.54M | 0.8% | $12.12 | -11.1% | COM | 26818M108 |
| MRNA | MODERNA INC | 200,000 | $20.66M | 0.8% | $111.55 | 0.0% | COM | 60770K107 |
| SLN | SILENCE THERAPEUTICS PLC | 1,951,580 | $19.16M | 0.7% | $16.79 | — | ADS | 82686Q101 |
| — | POINT BIOPHARMA GLOBAL INC | 2,781,565 | $18.55M | 0.7% | $7.55 | — | COM | 730541109 |
| ZURA | ZURA BIO LTD | 2,523,000 | $16.65M | 0.6% | $8.03 | -16.8% | CLASS A ORD SHS | G9TY5A101 |
| — | ORCHARD THERAPEUTICS PLC | 2,041,670 | $15.78M | 0.6% | $7.73 | — | SPON ADS NEW | 68570P200 |
| EWTX | EDGEWISE THERAPEUTICS INC | 2,750,000 | $15.76M | 0.6% | $10.10 | -32.7% | COM | 28036F105 |
| PRTA | PROTHENA CORP PLC | 250,000 | $12.06M | 0.5% | — | — | Put | G72800108 |
| — | NEKTAR THERAPEUTICS | 18,400,000 | $10.96M | 0.4% | $0.59 | — | COM | 640268108 |
| — | MORPHIC HLDG INC | 470,647 | $10.78M | 0.4% | $38.76 | — | COM | 61775R105 |
| AGIO | AGIOS PHARMACEUTICALS INC | 422,247 | $10.45M | 0.4% | $26.45 | 0.0% | COM | 00847X104 |
| ABOS | ACUMEN PHARMACEUTICALS INC | 2,513,044 | $10.43M | 0.4% | $8.05 | -23.2% | COM | 00509G209 |
| NUVB | NUVATION BIO INC | 7,720,688 | $10.35M | 0.4% | $4.49 | -62.9% | COM CL A | 67080N101 |
| — | VIGIL NEUROSCIENCE INC | 1,767,131 | $9.525M | 0.4% | $8.83 | — | COM | 92673K108 |
| RLMD | RELMADA THERAPEUTICS INC | 2,837,818 | $8.513M | 0.3% | $10.86 | -72.7% | COM | 75955J402 |
| — | ASTRIA THERAPEUTICS INC | 1,037,873 | $7.743M | 0.3% | $14.89 | — | COM | 04635X102 |
| TXG | 10X GENOMICS INC | 182,691 | $7.536M | 0.3% | $52.02 | 0.0% | CL A COM | 88025U109 |
| NVAX | NOVAVAX INC | 1,000,000 | $7.24M | 0.3% | $7.99 | 0.0% | COM NEW | 670002401 |
| — | ACELYRIN INC | 551,289 | $5.607M | 0.2% | $10.17 | — | COM | 00445A100 |
| GHRS | GH RESEARCH PLC | 499,400 | $5.019M | 0.2% | $21.97 | -47.4% | ORDINARY SHARES | G3855L106 |
| SYRS | SYROS PHARMACEUTICALS INC | 828,485 | $3.273M | 0.1% | $3.74 | 0.0% | COM NEW | 87184Q206 |
| SRRK | SCHOLAR ROCK HLDG CORP | 353,855 | $2.512M | 0.1% | $6.72 | 0.0% | COM | 80706P103 |
| CMPS | COMPASS PATHWAYS PLC | 328,424 | $2.43M | 0.1% | $8.28 | — | SPONSORED ADS | 20451W101 |
| HRTX | HERON THERAPEUTICS INC | 2,086,704 | $2.149M | 0.1% | $3.91 | -63.6% | COM | 427746102 |
| — | 89BIO INC | 91,078 | $1.406M | 0.1% | $7.98 | — | COM | 282559103 |
| IPSC | CENTURY THERAPEUTICS INC | 543,008 | $1.086M | 0.0% | $11.43 | -76.7% | COM | 15673T100 |