Boxer Capital Management, LLC Quant / Systematic

CIK: 0002018299 · Show all filings

Period: Q1 2025 (← Previous) (Next →)

Filing Date: Feb 17, 2026

Total Value ($000): $332,471 (100.0% shares, 0.0% debt)

Holdings (28)

RVMD REVOLUTION MEDICINES INC 14.0%

Value ($000) $46,604 Shares 1,317,977 Est. Cost $50.47 Unrealized -19.6%

NUVL NUVALENT INC 9.6%

Value ($000) $31,914 Shares 450,000 Est. Cost $93.39 Unrealized -16.3%

— MERUS N V 8.9%

Value ($000) $29,463 Shares 700,000 Est. Cost $42.05 Unrealized —

RNAM AVIDITY BIOSCIENCES INC 7.7%

Value ($000) $25,535 Shares 865,000 Est. Cost $41.79 Unrealized -25.5%

ANAB ANAPTYSBIO INC 7.3%

Value ($000) $24,167 Shares 1,300,000 Est. Cost $24.22 Unrealized -31.1%

XENE XENON PHARMACEUTICALS INC 6.1%

Value ($000) $20,130 Shares 600,000 Est. Cost $41.35 Unrealized -8.2%

REPL REPLIMUNE GROUP INC 5.3%

Value ($000) $17,514 Shares 1,796,341 Est. Cost $12.15 Unrealized +1.8%

APLS APELLIS PHARMACEUTICALS INC 4.7%

Value ($000) $15,593 Shares 713,000 Est. Cost $30.07 Unrealized -8.1%

— CHIMERIX INC 4.6%

Value ($000) $15,403 Shares 1,810,000 Est. Cost $3.48 Unrealized —

TNGX TANGO THERAPEUTICS INC 4.3%

Value ($000) $14,222 Shares 10,380,999 Est. Cost $4.64 Unrealized -47.1%

ELVN ENLIVEN THERAPEUTICS INC 4.0%

Value ($000) $13,212 Shares 671,358 Est. Cost $25.92 Unrealized -17.0%

ORIC ORIC PHARMACEUTICALS INC 2.9%

Value ($000) $9,668 Shares 1,732,571 Est. Cost $9.18 Unrealized -4.7%

DAWN DAY ONE BIOPHARMACEUTICALS I 2.8%

Value ($000) $9,436 Shares 1,189,943 Est. Cost $13.91 Unrealized -22.6%

KYMR KYMERA THERAPEUTICS INC 2.7%

Value ($000) $8,895 Shares 325,000 Est. Cost $45.17 Unrealized -19.3%

PRTA PROTHENA CORP PLC 2.6%

Value ($000) $8,539 Shares 690,000 Est. Cost $15.77 Unrealized -10.4%

QURE UNIQURE NV 2.4%

Value ($000) $7,950 Shares 750,000 Est. Cost $8.63 Unrealized +62.4%

LEGN LEGEND BIOTECH CORP 2.0%

Value ($000) $6,786 Shares 200,000 Est. Cost $32.54 Unrealized —

NRIX NURIX THERAPEUTICS INC 2.0%

Value ($000) $6,689 Shares 563,067 Est. Cost $22.92 Unrealized -27.0%

AMLX AMYLYX PHARMACEUTICALS INC 1.9%

Value ($000) $6,195 Shares 1,750,000 Est. Cost $4.71 Unrealized -24.4%

SLDB SOLID BIOSCIENCES INC 1.4%

Value ($000) $4,591 Shares 1,240,700 Est. Cost $4.28 Unrealized 0.0%

DNLI DENALI THERAPEUTICS INC 1.0%

Value ($000) $3,400 Shares 250,000 Est. Cost $19.16 Unrealized 0.0%

KOD KODIAK SCIENCES INC 0.9%

Value ($000) $2,908 Shares 1,035,000 Est. Cost $5.74 Unrealized -5.2%

PRLD PRELUDE THERAPEUTICS INC 0.5%

Value ($000) $1,623 Shares 2,108,014 Est. Cost $1.25 Unrealized -25.5%

TIL INSTIL BIO INC 0.4%

Value ($000) $1,391 Shares 80,125 Est. Cost $30.49 Unrealized -32.0%

BOLD BOUNDLESS BIO INC 0.1%

Value ($000) $378 Shares 250,000 Est. Cost $2.91 Unrealized -28.9%

CLYM CLIMB BIO INC 0.1%

Value ($000) $177 Shares 145,000 Est. Cost $3.62 Unrealized -55.2%

— NUVATION BIO INC 0.0%

Value ($000) $85 Shares 266,666 Est. Cost $0.23 Unrealized —

SRZNW SURROZEN INC 0.0%

Value ($000) $2 Shares 66,666 Est. Cost $0.02 Unrealized —

Ticker	Issuer	Shares	Value ($000)	%	Est. Cost	Unrealized	Class	CUSIP
RVMD	REVOLUTION MEDICINES INC	1,317,977	$46,604	14.0%	$50.47	-19.6%	COM	76155X100
NUVL	NUVALENT INC	450,000	$31,914	9.6%	$93.39	-16.3%	COM	670703107
—	MERUS N V	700,000	$29,463	8.9%	$42.05	—	COM	N5749R100
RNAM	AVIDITY BIOSCIENCES INC	865,000	$25,535	7.7%	$41.79	-25.5%	COM	05370A108
ANAB	ANAPTYSBIO INC	1,300,000	$24,167	7.3%	$24.22	-31.1%	COM	032724106
XENE	XENON PHARMACEUTICALS INC	600,000	$20,130	6.1%	$41.35	-8.2%	COM	98420N105
REPL	REPLIMUNE GROUP INC	1,796,341	$17,514	5.3%	$12.15	+1.8%	COM	76029N106
APLS	APELLIS PHARMACEUTICALS INC	713,000	$15,593	4.7%	$30.07	-8.1%	COM	03753U106
—	CHIMERIX INC	1,810,000	$15,403	4.6%	$3.48	—	COM	16934W106
TNGX	TANGO THERAPEUTICS INC	10,380,999	$14,222	4.3%	$4.64	-47.1%	COM	87583X109
ELVN	ENLIVEN THERAPEUTICS INC	671,358	$13,212	4.0%	$25.92	-17.0%	COM	29337E102
ORIC	ORIC PHARMACEUTICALS INC	1,732,571	$9,668	2.9%	$9.18	-4.7%	COM	68622P109
DAWN	DAY ONE BIOPHARMACEUTICALS I	1,189,943	$9,436	2.8%	$13.91	-22.6%	COM	23954D109
KYMR	KYMERA THERAPEUTICS INC	325,000	$8,895	2.7%	$45.17	-19.3%	COM	501575104
PRTA	PROTHENA CORP PLC	690,000	$8,539	2.6%	$15.77	-10.4%	SHS	G72800108
QURE	UNIQURE NV	750,000	$7,950	2.4%	$8.63	+62.4%	SHS	N90064101
LEGN	LEGEND BIOTECH CORP	200,000	$6,786	2.0%	$32.54	—	SPONSORED ADS	52490G102
NRIX	NURIX THERAPEUTICS INC	563,067	$6,689	2.0%	$22.92	-27.0%	COM	67080M103
AMLX	AMYLYX PHARMACEUTICALS INC	1,750,000	$6,195	1.9%	$4.71	-24.4%	COM	03237H101
SLDB	SOLID BIOSCIENCES INC	1,240,700	$4,591	1.4%	$4.28	0.0%	COM NEW	83422E204
DNLI	DENALI THERAPEUTICS INC	250,000	$3,400	1.0%	$19.16	0.0%	COM	24823R105
KOD	KODIAK SCIENCES INC	1,035,000	$2,908	0.9%	$5.74	-5.2%	COM	50015M109
PRLD	PRELUDE THERAPEUTICS INC	2,108,014	$1,623	0.5%	$1.25	-25.5%	COM	74065P101
TIL	INSTIL BIO INC	80,125	$1,391	0.4%	$30.49	-32.0%	COM NEW	45783C200
BOLD	BOUNDLESS BIO INC	250,000	$378	0.1%	$2.91	-28.9%	COM	10170A100
CLYM	CLIMB BIO INC	145,000	$177	0.1%	$3.62	-55.2%	COM	28658R106
—	NUVATION BIO INC	266,666	$85	0.0%	$0.23	—	*W EXP 02/10/202	67080N119
SRZNW	SURROZEN INC	66,666	$2	0.0%	$0.02	—	*W EXP 08/01/203	86889P117