Spruce Street Capital LP Diversified Active

Location: New York, NY

CIK: 0002050194 · Show all filings

Period: Q1 2026 (← Previous) (Next →)

Filing Date: May 14, 2026

Total Value: $416M (100.0% shares, 0.0% debt)

Holdings (28)

RLMD RELMADA THERAPEUTICS INC 10.3%

Value $43M Shares 6,262,114 Est. Cost $3.58 Unrealized +12.1%

KNSA KINIKSA PHARMACEUTICALS I 8.8%

Value $36.65M Shares 761,063 Est. Cost $41.42 Unrealized +4.2%

LBRX LB PHARMACEUTICALS INC 8.1%

Value $33.64M Shares 1,376,159 Est. Cost $18.79 Unrealized +19.1%

DNTH DIANTHUS THERAPEUTICS IN 7.5%

Value $31.33M Shares 373,274 Est. Cost $40.56 Unrealized +17.3%

RLAY RELAY THERAPEUTICS INC 7.1%

Value $29.69M Shares 2,984,125 Est. Cost $7.14 Unrealized +16.3%

ANRO ALTO NEUROSCIENCE INC 7.0%

Value $29.12M Shares 1,325,210 Est. Cost $16.06 Unrealized +4.4%

CNTA CENTESSA PHARMACEUTICALS 4.7%

Value $19.46M Shares 489,849 Est. Cost $37.38 Unrealized —

SVRA SAVARA INC 4.4%

Value $18.47M Shares 3,383,175 Est. Cost $5.13 Unrealized +11.1%

KALV KALVISTA PHARMACEUTICALS 4.3%

Value $18.07M Shares 897,681 Est. Cost $14.52 Unrealized +6.7%

PCVX VAXCYTE INC 3.4%

Value $14.28M Shares 245,709 Est. Cost $44.73 Unrealized +18.0%

ELVN ENLIVEN THERAPEUTICS INC 3.1%

Value $12.9M Shares 329,006 Est. Cost $19.92 Unrealized +28.5%

SRZN SURROZEN INC COM NEW 3.0%

Value $12.59M Shares 432,040 Est. Cost $16.18 Unrealized +37.4%

ENTA ENANTA PHARMACEUTICALS I 2.8%

Value $11.78M Shares 932,598 Est. Cost $13.16 Unrealized +2.5%

ALKS ALKERMES PLC 2.7%

Value $11.24M Shares 317,992 Est. Cost $32.34 Unrealized 0.0%

CATX PERSPECTIVE THERAPEUTICS 2.6%

Value $10.96M Shares 2,627,107 Est. Cost $3.84 Unrealized 0.0%

NERV MINERVA NEUROSCIENC 2.4%

Value $9.974M Shares 1,655,500 Est. Cost $3.71 Unrealized +33.7%

IPSC CENTURY THERAPEUTICS 2.2%

Value $9.173M Shares 4,059,054 Est. Cost $1.47 Unrealized +31.5%

ALMS ALUMIS INC 2.1%

Value $8.648M Shares 392,574 Est. Cost $24.33 Unrealized 0.0%

SABS SAB BIOTHERAPEUTICS IN 2.0%

Value $8.42M Shares 2,198,502 Est. Cost $3.29 Unrealized +21.6%

ERAS ERASCA INC 1.6%

Value $6.837M Shares 422,543 Est. Cost $2.81 Unrealized +256.4%

IKT INHIBIKASE THERAPEUTI 1.4%

Value $6.017M Shares 3,581,603 Est. Cost $1.59 Unrealized +9.0%

MAZE MAZE THERAPEUTICS INC 1.4%

Value $5.97M Shares 200,000 Est. Cost $44.04 Unrealized 0.0%

ANTX AN2 THERAPEUTICS INC 1.3%

Value $5.576M Shares 1,661,073 Est. Cost $1.13 Unrealized 0.0%

LXEO LEXEO THERAPEUTICS INC 1.3%

Value $5.33M Shares 928,593 Est. Cost $7.83 Unrealized -3.8%

HLXC HELIX ACQUISITION CORP III 1.2%

Value $5.08M Shares 500,000 Est. Cost $10.16 Unrealized —

ALEC ALECTOR INC 1.1%

Value $4.517M Shares 2,101,068 Est. Cost $1.84 Unrealized +3.8%

LONA LEONABIO INC 0.9%

Value $3.845M Shares 393,701 Est. Cost $4.58 Unrealized +22.8%

CRVS CORVUS PHARMACEUTICALS I 0.8%

Value $3.388M Shares 231,585 Est. Cost $16.29 Unrealized 0.0%

Ticker	Issuer	Shares	Value	%	Est. Cost	Unrealized	Class	CUSIP
RLMD	RELMADA THERAPEUTICS INC	6,262,114	$43M	10.3%	$3.58	+12.1%	COM	75955J402
KNSA	KINIKSA PHARMACEUTICALS I	761,063	$36.65M	8.8%	$41.42	+4.2%	ORD SHS CL A	G52694109
LBRX	LB PHARMACEUTICALS INC	1,376,159	$33.64M	8.1%	$18.79	+19.1%	COM SHS	50180M108
DNTH	DIANTHUS THERAPEUTICS IN	373,274	$31.33M	7.5%	$40.56	+17.3%	COM	252828108
RLAY	RELAY THERAPEUTICS INC	2,984,125	$29.69M	7.1%	$7.14	+16.3%	COM	75943R102
ANRO	ALTO NEUROSCIENCE INC	1,325,210	$29.12M	7.0%	$16.06	+4.4%	COM SHS	02157Q109
CNTA	CENTESSA PHARMACEUTICALS	489,849	$19.46M	4.7%	$37.38	—	SPONSORED ADS	152309100
SVRA	SAVARA INC	3,383,175	$18.47M	4.4%	$5.13	+11.1%	COM	805111101
KALV	KALVISTA PHARMACEUTICALS	897,681	$18.07M	4.3%	$14.52	+6.7%	COM	483497103
PCVX	VAXCYTE INC	245,709	$14.28M	3.4%	$44.73	+18.0%	COM	92243G108
ELVN	ENLIVEN THERAPEUTICS INC	329,006	$12.9M	3.1%	$19.92	+28.5%	COM	29337E102
SRZN	SURROZEN INC COM NEW	432,040	$12.59M	3.0%	$16.18	+37.4%	COM NEW	86889P208
ENTA	ENANTA PHARMACEUTICALS I	932,598	$11.78M	2.8%	$13.16	+2.5%	COM	29251M106
ALKS	ALKERMES PLC	317,992	$11.24M	2.7%	$32.34	0.0%	SHS	G01767105
CATX	PERSPECTIVE THERAPEUTICS	2,627,107	$10.96M	2.6%	$3.84	0.0%	COM NEW	46489V302
NERV	MINERVA NEUROSCIENC	1,655,500	$9.974M	2.4%	$3.71	+33.7%	COM NEW	603380205
IPSC	CENTURY THERAPEUTICS	4,059,054	$9.173M	2.2%	$1.47	+31.5%	COM	15673T100
ALMS	ALUMIS INC	392,574	$8.648M	2.1%	$24.33	0.0%	COM	022307102
SABS	SAB BIOTHERAPEUTICS IN	2,198,502	$8.42M	2.0%	$3.29	+21.6%	COM NEW	78397T202
ERAS	ERASCA INC	422,543	$6.837M	1.6%	$2.81	+256.4%	COM	29479A108
IKT	INHIBIKASE THERAPEUTI	3,581,603	$6.017M	1.4%	$1.59	+9.0%	COM NEW	45719W205
MAZE	MAZE THERAPEUTICS INC	200,000	$5.97M	1.4%	$44.04	0.0%	COM	578784100
ANTX	AN2 THERAPEUTICS INC	1,661,073	$5.576M	1.3%	$1.13	0.0%	COM	037326105
LXEO	LEXEO THERAPEUTICS INC	928,593	$5.33M	1.3%	$7.83	-3.8%	COM	52886X107
HLXC	HELIX ACQUISITION CORP III	500,000	$5.08M	1.2%	$10.16	—	USD CL A ORD SHS	G4444S107
ALEC	ALECTOR INC	2,101,068	$4.517M	1.1%	$1.84	+3.8%	COM	014442107
LONA	LEONABIO INC	393,701	$3.845M	0.9%	$4.58	+22.8%	COM	04746L203
CRVS	CORVUS PHARMACEUTICALS I	231,585	$3.388M	0.8%	$16.29	0.0%	COM	221015100