GSK plc Concentrated Active

CIK: 0001131399 · Show all filings

Period: Q4 2025

Filing Date: Feb 12, 2026

Total Value ($000): $799,023 (100.0% shares, 0.0% debt)

Holdings (15)

WVE WAVE LIFE SCIENCES LTD 38.8%

Value ($000) $310,177 Shares 18,245,691 Est. Cost $10.16 Unrealized 0.0%

CRSP CRISPR THERAPEUTICS AG 21.1%

Value ($000) $168,890 Shares 3,220,627 Est. Cost $59.89 Unrealized 0.0%

BNTX BIONTECH SE 10.6%

Value ($000) $84,711 Shares 889,824 Est. Cost $95.20 Unrealized —

VIR VIR BIOTECHNOLOGY INC 6.5%

Value ($000) $51,562 Shares 8,550,954 Est. Cost $5.95 Unrealized 0.0%

LYEL LYELL IMMUNOPHARMA INC 5.8%

Value ($000) $46,560 Shares 1,512,659 Est. Cost $22.38 Unrealized 0.0%

IDYA IDEAYA BIOSCIENCES INC 5.8%

Value ($000) $46,093 Shares 1,333,333 Est. Cost $31.88 Unrealized 0.0%

CYTK CYTOKINETICS INC 2.7%

Value ($000) $21,631 Shares 340,434 Est. Cost $62.21 Unrealized 0.0%

SPRO SPERO THERAPEUTICS INC 2.7%

Value ($000) $21,414 Shares 9,190,606 Est. Cost $2.32 Unrealized 0.0%

FULC FULCRUM THERAPEUTICS INC 2.5%

Value ($000) $20,196 Shares 1,785,714 Est. Cost $10.18 Unrealized 0.0%

BCYC BICYCLE THERAPEUTICS PLC 1.4%

Value ($000) $10,829 Shares 1,529,561 Est. Cost $7.08 Unrealized —

CVRX CVRX INC 0.9%

Value ($000) $7,154 Shares 1,007,583 Est. Cost $9.13 Unrealized 0.0%

NKTX NKARTA INC 0.7%

Value ($000) $5,829 Shares 3,150,732 Est. Cost $2.00 Unrealized 0.0%

RGNX REGENXBIO INC 0.5%

Value ($000) $3,909 Shares 271,456 Est. Cost $12.46 Unrealized 0.0%

SENS SENSEONICS HLDGS INC 0.0%

Value ($000) $60 Shares 10,856 Est. Cost $6.96 Unrealized 0.0%

HBIO HARVARD BIOSCIENCE INC 0.0%

Value ($000) $7 Shares 11,151 Est. Cost $0.59 Unrealized 0.0%

Ticker	Issuer	Shares	Value ($000)	%	Est. Cost	Unrealized	Class	CUSIP
WVE	WAVE LIFE SCIENCES LTD	18,245,691	$310,177	38.8%	$10.16	0.0%	SHS	Y95308105
CRSP	CRISPR THERAPEUTICS AG	3,220,627	$168,890	21.1%	$59.89	0.0%	NAMEN AKT	H17182108
BNTX	BIONTECH SE	889,824	$84,711	10.6%	$95.20	—	SPONSORED ADS	09075V102
VIR	VIR BIOTECHNOLOGY INC	8,550,954	$51,562	6.5%	$5.95	0.0%	COM	92764N102
LYEL	LYELL IMMUNOPHARMA INC	1,512,659	$46,560	5.8%	$22.38	0.0%	COM NEW	55083R203
IDYA	IDEAYA BIOSCIENCES INC	1,333,333	$46,093	5.8%	$31.88	0.0%	COM	45166A102
CYTK	CYTOKINETICS INC	340,434	$21,631	2.7%	$62.21	0.0%	COM NEW	23282W605
SPRO	SPERO THERAPEUTICS INC	9,190,606	$21,414	2.7%	$2.32	0.0%	COM	84833T103
FULC	FULCRUM THERAPEUTICS INC	1,785,714	$20,196	2.5%	$10.18	0.0%	COM	359616109
BCYC	BICYCLE THERAPEUTICS PLC	1,529,561	$10,829	1.4%	$7.08	—	SPONSORED ADS	088786108
CVRX	CVRX INC	1,007,583	$7,154	0.9%	$9.13	0.0%	COM	126638105
NKTX	NKARTA INC	3,150,732	$5,829	0.7%	$2.00	0.0%	COM	65487U108
RGNX	REGENXBIO INC	271,456	$3,909	0.5%	$12.46	0.0%	COM	75901B107
SENS	SENSEONICS HLDGS INC	10,856	$60	0.0%	$6.96	0.0%	COM	81727U303
HBIO	HARVARD BIOSCIENCE INC	11,151	$7	0.0%	$0.59	0.0%	COM	416906105