Novo Holdings A/S Long-Term Concentrated

Location: Hellerup, Denmark

CIK: 0001388325 · Show all filings

Period: Q1 2026 (← Previous)

Filing Date: May 15, 2026

Total Value: $1.234B (100.0% shares, 0.0% debt)

Holdings (22)

New Positions (1)

XENE XENON PHARMACEUTICALS INC 2.3%

Value $28.23M Shares 485,438 Est. Cost $41.98 Unrealized 0.0%

Ticker	Issuer	Shares	Value	%	Est. Cost	Unrealized	Class	CUSIP
XENE	XENON PHARMACEUTICALS INC	485,438	$28.23M	2.3%	$41.98	0.0%	COM	98420N105

Increased Positions (3)

MIRM MIRUM PHARMACEUTICALS INC 9.9%

Value $122M (+22.6%) Shares 1,325,000 (+4.8%) Est. Cost $16.14 Unrealized +498.1%

CRM SALESFORCE INC 5.9%

Value $73.4M (-16.1%) Shares 393,187 (+19.1%) Est. Cost $207.33 Unrealized +4.1%

BBOT BRIDGEBIO ONCOLOGY THERAPEUT 1.6%

Value $19.56M (-20.3%) Shares 2,185,923 (+11.5%) Est. Cost $11.31 Unrealized —

Ticker	Issuer	Shares	Value	%	Est. Cost	Unrealized	Class	CUSIP
MIRM	MIRUM PHARMACEUTICALS INC	1,325,000 (+4.8%)	$122M (+22.6%)	9.9%	$16.14	+498.1%	COM	604749101
CRM	SALESFORCE INC	393,187 (+19.1%)	$73.4M (-16.1%)	5.9%	$207.33	+4.1%	COM	79466L302
BBOT	BRIDGEBIO ONCOLOGY THERAPEUT	2,185,923 (+11.5%)	$19.56M (-20.3%)	1.6%	$11.31	—	COM NEW	107924102

Exited Positions (3)

ZBIO ZENAS BIOPHARMA INC 4.3%

Value $52.65M Shares 1,450,000 Est. Cost $14.60 Unrealized +49.9%

INSM INSMED INC 2.8%

Value $34.81M Shares 200,000 Est. Cost $23.10 Unrealized +588.4%

IOBT IO BIOTECH INC 0.1%

Value $1.53M Shares 2,512,453 Est. Cost $6.26 Unrealized -93.5%

Ticker	Issuer	Shares	Value	%	Est. Cost	Unrealized	Class	CUSIP
ZBIO	ZENAS BIOPHARMA INC	1,450,000	$52.65M	4.3%	$14.60	+49.9%	—	98937L105
INSM	INSMED INC	200,000	$34.81M	2.8%	$23.10	+588.4%	—	457669307
IOBT	IO BIOTECH INC	2,512,453	$1.53M	0.1%	$6.26	-93.5%	—	449778109

Decreased Positions (7)

VRDN VIRIDIAN THERAPEUTICS INC 3.2%

Value $39.12M (-47.2%) Shares 2,000,000 (-16.0%) Est. Cost $16.63 Unrealized +85.5%

ELVN ENLIVEN THERAPEUTICS INC 4.1%

Value $50.18M (+120.1%) Shares 1,280,000 (-13.5%) Est. Cost $19.25 Unrealized +33.0%

CRNX CRINETICS PHARMACEUTICALS IN 4.6%

Value $56.3M (-25.6%) Shares 1,550,000 (-4.6%) Est. Cost $25.38 Unrealized +93.9%

VALN VALNEVA SE 0.5%

Value $6.609M (-67.5%) Shares 1,057,421 (-54.1%) Est. Cost $5.67 Unrealized —

PCVX VAXCYTE INC 4.0%

Value $49.97M (+18.2%) Shares 860,000 (-6.1%) Est. Cost $39.88 Unrealized +32.3%

APGE APOGEE THERAPEUTICS INC 3.1%

Value $37.88M (-12.0%) Shares 450,000 (-21.1%) Est. Cost $41.12 Unrealized +75.7%

ASML ASML HOLDING N V 10.2%

Value $125M (+2.9%) Shares 94,946 (-16.7%) Est. Cost $662.32 Unrealized —

Ticker	Issuer	Shares	Value	%	Est. Cost	Unrealized	Class	CUSIP
VRDN	VIRIDIAN THERAPEUTICS INC	2,000,000 (-16.0%)	$39.12M (-47.2%)	3.2%	$16.63	+85.5%	COM	92790C104
ELVN	ENLIVEN THERAPEUTICS INC	1,280,000 (-13.5%)	$50.18M (+120.1%)	4.1%	$19.25	+33.0%	COM	29337E102
CRNX	CRINETICS PHARMACEUTICALS IN	1,550,000 (-4.6%)	$56.3M (-25.6%)	4.6%	$25.38	+93.9%	COM	22663K107
VALN	VALNEVA SE	1,057,421 (-54.1%)	$6.609M (-67.5%)	0.5%	$5.67	—	SPONSORED ADS	92025Y103
PCVX	VAXCYTE INC	860,000 (-6.1%)	$49.97M (+18.2%)	4.0%	$39.88	+32.3%	COM	92243G108
APGE	APOGEE THERAPEUTICS INC	450,000 (-21.1%)	$37.88M (-12.0%)	3.1%	$41.12	+75.7%	COM	03770N101
ASML	ASML HOLDING N V	94,946 (-16.7%)	$125M (+2.9%)	10.2%	$662.32	—	N Y REGISTRY SHS	N07059210

Unchanged Positions (11)

EWTX EDGEWISE THERAPEUTICS INC 13.7%

Value $169M Shares 5,350,000 Est. Cost $18.02 Unrealized +56.4%

BN BROOKFIELD CORP 11.5%

Value $141M Shares 3,496,245 Est. Cost $29.96 Unrealized +55.8%

MPLT MAPLIGHT THERAPEUTICS INC 6.1%

Value $74.95M Shares 3,686,622 Est. Cost $16.75 Unrealized +5.2%

FDMT 4D MOLECULAR THERAPEUTICS IN 2.8%

Value $33.99M Shares 3,650,737 Est. Cost $12.43 Unrealized -31.0%

AVBP ARRIVENT BIOPHARMA INC 3.6%

Value $44.81M Shares 1,942,142 Est. Cost $20.49 Unrealized +7.7%

CLDX CELLDEX THERAPEUTICS INC NEW 3.1%

Value $38.06M Shares 1,200,000 Est. Cost $34.88 Unrealized -27.1%

BABA ALIBABA GROUP HLDG LTD 2.6%

Value $32.28M Shares 257,327 Est. Cost $165.09 Unrealized —

BMRN BIOMARIN PHARMACEUTICAL INC 3.0%

Value $37.28M Shares 660,000 Est. Cost $77.70 Unrealized -24.4%

PHVS PHARVARIS N V 4.0%

Value $49.44M Shares 1,750,000 Est. Cost $15.36 Unrealized +74.1%

LNZA LANZATECH GLOBAL INC 0.2%

Value $2.532M Shares 158,148 Est. Cost $28.70 Unrealized -58.8%

MQ MARQETA INC 0.1%

Value $1.802M Shares 441,558 Est. Cost $22.37 Unrealized -80.7%

Ticker	Issuer	Shares	Value	%	Est. Cost	Unrealized	Class	CUSIP
EWTX	EDGEWISE THERAPEUTICS INC	5,350,000	$169M	13.7%	$18.02	+56.4%	COM	28036F105
BN	BROOKFIELD CORP	3,496,245	$141M	11.5%	$29.96	+55.8%	CL A LTD VT SH	11271J107
MPLT	MAPLIGHT THERAPEUTICS INC	3,686,622	$74.95M	6.1%	$16.75	+5.2%	COM	56565P103
FDMT	4D MOLECULAR THERAPEUTICS IN	3,650,737	$33.99M	2.8%	$12.43	-31.0%	COM	35104E100
AVBP	ARRIVENT BIOPHARMA INC	1,942,142	$44.81M	3.6%	$20.49	+7.7%	COM	04272N102
CLDX	CELLDEX THERAPEUTICS INC NEW	1,200,000	$38.06M	3.1%	$34.88	-27.1%	COM NEW	15117B202
BABA	ALIBABA GROUP HLDG LTD	257,327	$32.28M	2.6%	$165.09	—	SPONSORED ADS	01609W102
BMRN	BIOMARIN PHARMACEUTICAL INC	660,000	$37.28M	3.0%	$77.70	-24.4%	COM	09061G101
PHVS	PHARVARIS N V	1,750,000	$49.44M	4.0%	$15.36	+74.1%	COM	N69605108
LNZA	LANZATECH GLOBAL INC	158,148	$2.532M	0.2%	$28.70	-58.8%	COM NEW	51655R200
MQ	MARQETA INC	441,558	$1.802M	0.1%	$22.37	-80.7%	CLASS A COM	57142B104