Prosight Management, LP Quant / Systematic

Ticker	Issuer	Shares	Value ($000)	%	Est. Cost	Unrealized	Class	CUSIP
NKTR	NEKTAR THERAPEUTICS	554,633	$23,450	4.8%	$55.96	0.0%	COM NEW	640268306
VEEV	VEEVA SYS INC	90,133	$20,120	4.2%	$265.35	0.0%	CL A COM	922475108
PHR	PHREESIA INC	977,152	$16,533	3.4%	$20.63	0.0%	COM	71944F106
AVTR	AVANTOR INC	898,499	$10,297	2.1%	$12.31	0.0%	COM	05352A100
LH	LABCORP HOLDINGS INC	34,532	$8,663	1.8%	$265.14	0.0%	COM SHS	504922105
WGS	GENEDX HOLDINGS CORP	55,000	$7,153	1.5%	$137.25	0.0%	COM CL A	81663L200
ALNY	ALNYLAM PHARMACEUTICALS INC	17,109	$6,803	1.4%	$442.56	0.0%	COM	02043Q107
TERN	TERNS PHARMACEUTICALS INC	95,000	$3,838	0.8%	$23.11	0.0%	COM	880881107
ABVX	ABIVAX SA	17,000	$2,293	0.5%	$134.85	—	SPONSORED ADS	00370M103
ACET	ADICET BIO INC	250,244	$2,107	0.4%	$11.05	0.0%	COM NEW	007002207
TEM	TEMPUS AI INC	35,000	$2,067	0.4%	$78.23	0.0%	CL A	88023B103

Increased Positions (10)

PRCT PROCEPT BIOROBOTICS CORP 9.0%

Value ($000) $43,415 (+1480.0%) Shares 1,380,000 (+1692.4%) Est. Cost $33.86 Unrealized -2.1%

BSX BOSTON SCIENTIFIC CORP 4.1%

Value ($000) $20,024 (+169.5%) Shares 210,000 (+176.0%) Est. Cost $100.04 Unrealized -2.0%

JANX JANUX THERAPEUTICS INC 6.8%

Value ($000) $33,017 (+56.1%) Shares 2,392,523 (+176.5%) Est. Cost $29.10 Unrealized -19.2%

CON CONCENTRA GROUP HOLDINGS PAR 3.6%

Value ($000) $17,535 (+37.3%) Shares 891,030 (+46.1%) Est. Cost $20.82 Unrealized -4.1%

SEM SELECT MED HLDGS CORP 3.2%

Value ($000) $15,371 (+36.8%) Shares 1,035,086 (+18.3%) Est. Cost $14.11 Unrealized -0.1%

PLRX PLIANT THERAPEUTICS INC 0.4%

Value ($000) $1,898 (+6159.7%) Shares 1,555,744 (+7493.8%) Est. Cost $1.53 Unrealized -1.5%

OKUR ONKURE THERAPEUTICS INC 0.5%

Value ($000) $2,369 (+221.5%) Shares 816,909 (+204.9%) Est. Cost $4.07 Unrealized -26.5%

TBI TRUEBLUE INC 0.4%

Value ($000) $2,014 (+313.3%) Shares 442,554 (+456.8%) Est. Cost $5.35 Unrealized -4.0%

CRBP CORBUS PHARMACEUTICALS HLDGS 1.2%

Value ($000) $5,567 (+28.1%) Shares 683,872 (+99.1%) Est. Cost $16.35 Unrealized -24.5%

ADCT ADC THERAPEUTICS SA 6.2%

Value ($000) $29,925 (+0.1%) Shares 8,477,338 (+13.5%) Est. Cost $3.23 Unrealized +25.8%

Ticker	Issuer	Shares	Value ($000)	%	Est. Cost	Unrealized	Class	CUSIP
PRCT	PROCEPT BIOROBOTICS CORP	1,380,000 (+1692.4%)	$43,415 (+1480.0%)	9.0%	$33.86	-2.1%	COM	74276L105
BSX	BOSTON SCIENTIFIC CORP	210,000 (+176.0%)	$20,024 (+169.5%)	4.1%	$100.04	-2.0%	COM	101137107
JANX	JANUX THERAPEUTICS INC	2,392,523 (+176.5%)	$33,017 (+56.1%)	6.8%	$29.10	-19.2%	COM	47103J105
CON	CONCENTRA GROUP HOLDINGS PAR	891,030 (+46.1%)	$17,535 (+37.3%)	3.6%	$20.82	-4.1%	COMMON STOCK	20603L102
SEM	SELECT MED HLDGS CORP	1,035,086 (+18.3%)	$15,371 (+36.8%)	3.2%	$14.11	-0.1%	COM	81619Q105
PLRX	PLIANT THERAPEUTICS INC	1,555,744 (+7493.8%)	$1,898 (+6159.7%)	0.4%	$1.53	-1.5%	COM	729139105
OKUR	ONKURE THERAPEUTICS INC	816,909 (+204.9%)	$2,369 (+221.5%)	0.5%	$4.07	-26.5%	COM CL A	68277Q105
TBI	TRUEBLUE INC	442,554 (+456.8%)	$2,014 (+313.3%)	0.4%	$5.35	-4.0%	COM	89785X101
CRBP	CORBUS PHARMACEUTICALS HLDGS	683,872 (+99.1%)	$5,567 (+28.1%)	1.2%	$16.35	-24.5%	COM NEW	21833P301
ADCT	ADC THERAPEUTICS SA	8,477,338 (+13.5%)	$29,925 (+0.1%)	6.2%	$3.23	+25.8%	SHS	H0036K147

Exited Positions (15)

ISRG INTUITIVE SURGICAL INC 4.5%

Value ($000) $21,785 Shares 48,711 Est. Cost $479.87 Unrealized +10.9%

DXCM DEXCOM INC 2.7%

Value ($000) $13,136 Shares 195,217 Est. Cost $78.87 Unrealized -18.0%

— CORCEPT THERAPEUTICS INC 2.5%

Value ($000) $12,284 Shares 147,800 Est. Cost — Unrealized —

BHVN BIOHAVEN LTD 1.9%

Value ($000) $9,006 Shares 600,000 Est. Cost $20.40 Unrealized -39.3%

VRTX VERTEX PHARMACEUTICALS INC 1.7%

Value ($000) $8,029 Shares 20,500 Est. Cost $417.92 Unrealized +3.1%

ACHC ACADIA HEALTHCARE COMPANY IN 1.3%

Value ($000) $6,190 Shares 250,000 Est. Cost $41.81 Unrealized -54.7%

ALGN ALIGN TECHNOLOGY INC 0.5%

Value ($000) $2,435 Shares 19,442 Est. Cost $156.63 Unrealized -8.5%

ARGX ARGENX SE 0.5%

Value ($000) $2,434 Shares 3,300 Est. Cost $576.53 Unrealized —

TWST TWIST BIOSCIENCE CORP 0.4%

Value ($000) $2,111 Shares 75,000 Est. Cost $30.29 Unrealized +3.0%

— AKERO THERAPEUTICS INC 0.4%

Value ($000) $1,855 Shares 39,072 Est. Cost $47.48 Unrealized —

CTMX CYTOMX THERAPEUTICS INC 0.4%

Value ($000) $1,802 Shares 564,800 Est. Cost $1.23 Unrealized +209.8%

SGHT SIGHT SCIENCES INC 0.3%

Value ($000) $1,513 Shares 439,941 Est. Cost $5.64 Unrealized +13.3%

SDGR SCHRODINGER INC 0.1%

Value ($000) $699 Shares 34,830 Est. Cost $20.09 Unrealized -5.6%

PRTA PROTHENA CORP PLC 0.0%

Value ($000) $195 Shares 20,000 Est. Cost $26.88 Unrealized -62.1%

ACTU ACTUATE THERAPEUTICS ORD 0.0%

Value ($000) $6 Shares 885 Est. Cost $7.25 Unrealized -5.2%

Ticker	Issuer	Shares	Value ($000)	%	Est. Cost	Unrealized	Class	CUSIP
ISRG	INTUITIVE SURGICAL INC	48,711	$21,785	4.5%	$479.87	+10.9%	—	46120E602
DXCM	DEXCOM INC	195,217	$13,136	2.7%	$78.87	-18.0%	—	252131107
—	CORCEPT THERAPEUTICS INC	147,800	$12,284	2.5%	—	—	CALL	218352902
BHVN	BIOHAVEN LTD	600,000	$9,006	1.9%	$20.40	-39.3%	—	G1110E107
VRTX	VERTEX PHARMACEUTICALS INC	20,500	$8,029	1.7%	$417.92	+3.1%	—	92532F100
ACHC	ACADIA HEALTHCARE COMPANY IN	250,000	$6,190	1.3%	$41.81	-54.7%	—	00404A109
ALGN	ALIGN TECHNOLOGY INC	19,442	$2,435	0.5%	$156.63	-8.5%	—	016255101
ARGX	ARGENX SE	3,300	$2,434	0.5%	$576.53	—	—	04016X101
TWST	TWIST BIOSCIENCE CORP	75,000	$2,111	0.4%	$30.29	+3.0%	—	90184D100
—	AKERO THERAPEUTICS INC	39,072	$1,855	0.4%	$47.48	—	—	00973Y108
CTMX	CYTOMX THERAPEUTICS INC	564,800	$1,802	0.4%	$1.23	+209.8%	—	23284F105
SGHT	SIGHT SCIENCES INC	439,941	$1,513	0.3%	$5.64	+13.3%	—	82657M105
SDGR	SCHRODINGER INC	34,830	$699	0.1%	$20.09	-5.6%	—	80810D103
PRTA	PROTHENA CORP PLC	20,000	$195	0.0%	$26.88	-62.1%	—	G72800108
ACTU	ACTUATE THERAPEUTICS ORD	885	$6	0.0%	$7.25	-5.2%	—	005083100

Decreased Positions (16)

BBIO BRIDGEBIO PHARMA INC 0.5%

Value ($000) $2,295 (-83.3%) Shares 30,000 (-88.7%) Est. Cost $30.67 Unrealized +114.0%

MGTX MEIRAGTX HLDGS PLC 5.3%

Value ($000) $25,518 (-24.2%) Shares 3,209,788 (-21.5%) Est. Cost $6.93 Unrealized +19.9%

ROIV ROIVANT SCIENCES LTD 2.8%

Value ($000) $13,609 (-32.6%) Shares 627,162 (-53.0%) Est. Cost $10.80 Unrealized +82.7%

IMVT IMMUNOVANT INC 1.3%

Value ($000) $6,187 (-45.0%) Shares 243,404 (-65.2%) Est. Cost $23.65 Unrealized -5.7%

GLPG GALAPAGOS NV 7.3%

Value ($000) $35,123 (-11.8%) Shares 1,074,112 (-6.6%) Est. Cost $33.19 Unrealized —

STTK SHATTUCK LABS INC 1.8%

Value ($000) $8,692 (-33.3%) Shares 2,381,502 (-56.3%) Est. Cost $5.19 Unrealized -54.1%

KIDS ORTHOPEDIATRICS CORP 0.5%

Value ($000) $2,429 (-57.5%) Shares 136,741 (-55.7%) Est. Cost $20.84 Unrealized -16.0%

FOLD AMICUS THERAPEUTICS INC 3.4%

Value ($000) $16,376 (+21.6%) Shares 1,150,000 (-32.7%) Est. Cost $7.87 Unrealized +24.9%

CDNA CAREDX INC 1.0%

Value ($000) $4,710 (-35.7%) Shares 250,000 (-50.4%) Est. Cost $17.83 Unrealized -6.0%

KURA KURA ONCOLOGY INC 5.4%

Value ($000) $26,283 (+7.7%) Shares 2,529,600 (-8.3%) Est. Cost $9.51 Unrealized +10.3%

RCKT ROCKET PHARMACEUTICALS INC 0.5%

Value ($000) $2,611 (-36.8%) Shares 743,942 (-41.3%) Est. Cost $13.68 Unrealized -75.0%

SNDX SYNDAX PHARMACEUTICALS INC 2.9%

Value ($000) $13,972 (-9.5%) Shares 665,000 (-33.7%) Est. Cost $16.38 Unrealized +6.5%

CRNX CRINETICS PHARMACEUTICALS IN 2.5%

Value ($000) $12,238 (-10.6%) Shares 262,904 (-20.0%) Est. Cost $30.98 Unrealized +43.7%

ZYME ZYMEWORKS INC 2.9%

Value ($000) $13,965 (+9.1%) Shares 530,393 (-29.2%) Est. Cost $10.69 Unrealized +104.1%

TECX TECTONIC THERAPEUTIC INC 1.0%

Value ($000) $4,902 (-17.6%) Shares 235,000 (-38.0%) Est. Cost $31.39 Unrealized -40.8%

RNTX REIN THERAPEUTICS INC 0.1%

Value ($000) $513 (-21.0%) Shares 442,600 (-22.1%) Est. Cost $2.99 Unrealized -53.9%

Ticker	Issuer	Shares	Value ($000)	%	Est. Cost	Unrealized	Class	CUSIP
BBIO	BRIDGEBIO PHARMA INC	30,000 (-88.7%)	$2,295 (-83.3%)	0.5%	$30.67	+114.0%	COM	10806X102
MGTX	MEIRAGTX HLDGS PLC	3,209,788 (-21.5%)	$25,518 (-24.2%)	5.3%	$6.93	+19.9%	COM	G59665102
ROIV	ROIVANT SCIENCES LTD	627,162 (-53.0%)	$13,609 (-32.6%)	2.8%	$10.80	+82.7%	SHS	G76279101
IMVT	IMMUNOVANT INC	243,404 (-65.2%)	$6,187 (-45.0%)	1.3%	$23.65	-5.7%	COM	45258J102
GLPG	GALAPAGOS NV	1,074,112 (-6.6%)	$35,123 (-11.8%)	7.3%	$33.19	—	SPON ADR	36315X101
STTK	SHATTUCK LABS INC	2,381,502 (-56.3%)	$8,692 (-33.3%)	1.8%	$5.19	-54.1%	COM	82024L103
KIDS	ORTHOPEDIATRICS CORP	136,741 (-55.7%)	$2,429 (-57.5%)	0.5%	$20.84	-16.0%	COM	68752L100
FOLD	AMICUS THERAPEUTICS INC	1,150,000 (-32.7%)	$16,376 (+21.6%)	3.4%	$7.87	+24.9%	COM	03152W109
CDNA	CAREDX INC	250,000 (-50.4%)	$4,710 (-35.7%)	1.0%	$17.83	-6.0%	COM	14167L103
KURA	KURA ONCOLOGY INC	2,529,600 (-8.3%)	$26,283 (+7.7%)	5.4%	$9.51	+10.3%	COM	50127T109
RCKT	ROCKET PHARMACEUTICALS INC	743,942 (-41.3%)	$2,611 (-36.8%)	0.5%	$13.68	-75.0%	COM	77313F106
SNDX	SYNDAX PHARMACEUTICALS INC	665,000 (-33.7%)	$13,972 (-9.5%)	2.9%	$16.38	+6.5%	COM	87164F105
CRNX	CRINETICS PHARMACEUTICALS IN	262,904 (-20.0%)	$12,238 (-10.6%)	2.5%	$30.98	+43.7%	COM	22663K107
ZYME	ZYMEWORKS INC	530,393 (-29.2%)	$13,965 (+9.1%)	2.9%	$10.69	+104.1%	COM	98985Y108
TECX	TECTONIC THERAPEUTIC INC	235,000 (-38.0%)	$4,902 (-17.6%)	1.0%	$31.39	-40.8%	COM	878972108
RNTX	REIN THERAPEUTICS INC	442,600 (-22.1%)	$513 (-21.0%)	0.1%	$2.99	-53.9%	COM NEW	00887A204

Unchanged Positions (1)

ICLR ICON PLC 4.1%

Value ($000) $20,044 Shares 110,000 Est. Cost $194.71 Unrealized -8.5%

Ticker	Issuer	Shares	Value ($000)	%	Est. Cost	Unrealized	Class	CUSIP
ICLR	ICON PLC	110,000	$20,044	4.1%	$194.71	-8.5%	SHS	G4705A100