Kalehua Capital Management LLC Quant / Systematic

Location: Dallas, TX

CIK: 0002106181 · Show all filings

Period: Q1 2026 (← Previous)

Filing Date: May 15, 2026

Total Value: $120M

Holdings (25)

New Positions (9)

MANE Veradermics Inc 5.4%

Value $6.497M Shares 102,879 Est. Cost $63.15 Unrealized —

ACRS ACLARIS THERAPEUTICS INC 4.2%

Value $5.016M Shares 1,337,556 Est. Cost $3.33 Unrealized 0.0%

GLTO Damora Therapeutics Inc 3.0%

Value $3.6M Shares 139,000 Est. Cost $25.80 Unrealized 0.0%

QURE Uniqure NV 2.9%

Value $3.461M Shares 211,702 Est. Cost $23.55 Unrealized 0.0%

GOSS Gossamer Bio Inc 2.0%

Value $2.454M Shares 7,471,840 Est. Cost $2.26 Unrealized 0.0%

PEPG PepGen Inc 1.1%

Value $1.292M Shares 729,961 Est. Cost $5.83 Unrealized 0.0%

KRRO KORRO BIO INC 1.0%

Value $1.238M Shares 109,376 Est. Cost $10.79 Unrealized 0.0%

TIL Instil Bio Inc 1.0%

Value $1.152M Shares 139,849 Est. Cost $7.86 Unrealized 0.0%

LOOP LONGEVERON INC 0.3%

Value $361K Shares 347,539 Est. Cost $1.20 Unrealized 0.0%

Ticker	Issuer	Shares	Value	%	Est. Cost	Unrealized	Class	CUSIP
MANE	Veradermics Inc	102,879	$6.497M	5.4%	$63.15	—	—	922967104
ACRS	ACLARIS THERAPEUTICS INC	1,337,556	$5.016M	4.2%	$3.33	0.0%	—	00461U105
GLTO	Damora Therapeutics Inc	139,000	$3.6M	3.0%	$25.80	0.0%	—	36322Q206
QURE	Uniqure NV	211,702	$3.461M	2.9%	$23.55	0.0%	—	N90064101
GOSS	Gossamer Bio Inc	7,471,840	$2.454M	2.0%	$2.26	0.0%	—	38341P102
PEPG	PepGen Inc	729,961	$1.292M	1.1%	$5.83	0.0%	—	713317105
KRRO	KORRO BIO INC	109,376	$1.238M	1.0%	$10.79	0.0%	—	500946108
TIL	Instil Bio Inc	139,849	$1.152M	1.0%	$7.86	0.0%	—	45783C200
LOOP	LONGEVERON INC	347,539	$361K	0.3%	$1.20	0.0%	—	543518104

Increased Positions (1)

IKT Inhibikase Therapeutics Inc 3.7%

Value $4.49M (+25.2%) Shares 2,672,608 (+52.7%) Est. Cost $1.64 Unrealized +5.7%

Ticker	Issuer	Shares	Value	%	Est. Cost	Unrealized	Class	CUSIP
IKT	Inhibikase Therapeutics Inc	2,672,608 (+52.7%)	$4.49M (+25.2%)	3.7%	$1.64	+5.7%	—	45719W205

Exited Positions (3)

ALLO Allogene Therapeutics Inc 2.9%

Value $3.488M Shares 2,546,129 Est. Cost $1.32 Unrealized +31.7%

ORIC Oric Pharmaceuticals Inc 1.8%

Value $2.185M Shares 267,059 Est. Cost $11.51 Unrealized -6.5%

VRCA Verrica Pharmaceuticals Inc 1.6%

Value $1.959M Shares 235,779 Est. Cost $5.54 Unrealized +26.6%

Ticker	Issuer	Shares	Value	%	Est. Cost	Unrealized	Class	CUSIP
ALLO	Allogene Therapeutics Inc	2,546,129	$3.488M	2.9%	$1.32	+31.7%	—	019770106
ORIC	Oric Pharmaceuticals Inc	267,059	$2.185M	1.8%	$11.51	-6.5%	—	68622P109
VRCA	Verrica Pharmaceuticals Inc	235,779	$1.959M	1.6%	$5.54	+26.6%	—	92511W207

Decreased Positions (3)

BOXX Alpha Architect 1-3 Month Box ETF 11.5%

Value $13.77M (-48.2%) Shares 118,422 (-48.7%) Est. Cost $115.10 Unrealized —

KLRS Kalaris Therapeutics Inc 0.7%

Value $782K (-33.7%) Shares 135,585 (-3.1%) Est. Cost $6.39 Unrealized +46.6%

DMAC DiaMedica Therapeutics Inc 0.4%

Value $423K (-44.3%) Shares 62,488 (-34.5%) Est. Cost $7.48 Unrealized +11.1%

Ticker	Issuer	Shares	Value	%	Est. Cost	Unrealized	Class	CUSIP
BOXX	Alpha Architect 1-3 Month Box ETF	118,422 (-48.7%)	$13.77M (-48.2%)	11.5%	$115.10	—	—	02072L565
KLRS	Kalaris Therapeutics Inc	135,585 (-3.1%)	$782K (-33.7%)	0.7%	$6.39	+46.6%	—	482929106
DMAC	DiaMedica Therapeutics Inc	62,488 (-34.5%)	$423K (-44.3%)	0.4%	$7.48	+11.1%	—	25253X207

Unchanged Positions (12)

SRZN Surrozen Inc 9.3%

Value $11.22M Shares 385,178 Est. Cost $16.18 Unrealized +37.4%

ORKA Oruka Therapeutics Inc 4.8%

Value $5.814M Shares 118,524 Est. Cost $27.86 Unrealized +16.5%

RLAY Relay Therapeutics Inc 7.5%

Value $8.969M Shares 901,457 Est. Cost $7.14 Unrealized +16.3%

CMPS Compass Pathways PLC 3.8%

Value $4.533M Shares 819,692 Est. Cost $6.90 Unrealized —

LONA LeonaBio Inc 3.4%

Value $4.047M Shares 393,701 Est. Cost $4.58 Unrealized +22.8%

MLTX MoonLake Immunotherapeutics 2.7%

Value $3.276M Shares 175,734 Est. Cost $11.80 Unrealized +36.0%

TYRA Tyra Biosciences Inc 2.4%

Value $2.852M Shares 74,465 Est. Cost $18.37 Unrealized +64.7%

SEPN Septerna Inc 3.9%

Value $4.675M Shares 194,544 Est. Cost $23.88 Unrealized +11.0%

XFOR X4 Pharmaceuticals Inc 12.8%

Value $15.38M Shares 3,722,840 Est. Cost $3.63 Unrealized +0.1%

SION Sionna Therapeutics Inc 6.6%

Value $7.901M Shares 197,072 Est. Cost $37.92 Unrealized +3.5%

PHVS Pharvaris NV 4.7%

Value $5.615M Shares 198,772 Est. Cost $24.09 Unrealized +11.0%

TNYA Tenaya Therapeutics Inc 1.2%

Value $1.385M Shares 2,000,000 Est. Cost $1.36 Unrealized -46.6%

Ticker	Issuer	Shares	Value	%	Est. Cost	Unrealized	Class	CUSIP
SRZN	Surrozen Inc	385,178	$11.22M	9.3%	$16.18	+37.4%	—	86889P208
ORKA	Oruka Therapeutics Inc	118,524	$5.814M	4.8%	$27.86	+16.5%	—	687604108
RLAY	Relay Therapeutics Inc	901,457	$8.969M	7.5%	$7.14	+16.3%	—	75943R102
CMPS	Compass Pathways PLC	819,692	$4.533M	3.8%	$6.90	—	—	20451W101
LONA	LeonaBio Inc	393,701	$4.047M	3.4%	$4.58	+22.8%	—	04746L203
MLTX	MoonLake Immunotherapeutics	175,734	$3.276M	2.7%	$11.80	+36.0%	—	61559X104
TYRA	Tyra Biosciences Inc	74,465	$2.852M	2.4%	$18.37	+64.7%	—	90240B106
SEPN	Septerna Inc	194,544	$4.675M	3.9%	$23.88	+11.0%	—	81734D104
XFOR	X4 Pharmaceuticals Inc	3,722,840	$15.38M	12.8%	$3.63	+0.1%	—	98420X202
SION	Sionna Therapeutics Inc	197,072	$7.901M	6.6%	$37.92	+3.5%	—	829401108
PHVS	Pharvaris NV	198,772	$5.615M	4.7%	$24.09	+11.0%	—	N69605108
TNYA	Tenaya Therapeutics Inc	2,000,000	$1.385M	1.2%	$1.36	-46.6%	—	87990A106