ARCA BIOPHARMA INC

CUSIP: 00211Y407 Class: COM PAR$.001

TWO SIGMA SECURITIES, LLC's Holding History (CIK: 0001450144)

Note: Option positions (PUT/CALL) are excluded.

Q1 2019
Shares 12,428 Value ($000) $5 Avg Close — Range —
Q1 2018
Shares 32,337 Value ($000) $16 Avg Close — Range —