AARDVARK THERAPEUTICS INC

Ticker: AARD CUSIP: 002942100 Class: Common Stock

TWO SIGMA INVESTMENTS, LP's Holding History (CIK: 0001179392)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 128,786 Value ($000) $1,690 Avg Close $12.48 Range $8.82 - $17.94

Q3 2025

Shares 63,569 Value ($000) $845 Avg Close $11.28 Range $7.50 - $15.17

Q1 2025

Shares 15,424 Value ($000) $116 Avg Close $11.23 Range $6.79 - $19.58

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	128,786	$1,690	$12.48	$8.82 - $17.94
Q3 2025	63,569	$845	$11.28	$7.50 - $15.17
Q1 2025	15,424	$116	$11.23	$6.79 - $19.58