ACADIA PHARMACEUTICALS INC

Ticker: ACAD CUSIP: 004225108 Class: Common Stock

TWO SIGMA ADVISERS, LP's Holding History (CIK: 0001478735)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 370,200 Value ($000) $9,888 Avg Close $23.90 Range $19.69 - $28.35

Q3 2025

Shares 98,400 Value ($000) $2,100 Avg Close $23.65 Range $20.02 - $26.65

Q2 2025

Shares 194,900 Value ($000) $4,204 Avg Close $18.59 Range $13.40 - $25.23

Q1 2025

Shares 967,500 Value ($000) $16,070 Avg Close $18.17 Range $16.28 - $20.68

Q4 2024

Shares 1,263,200 Value ($000) $23,180 Avg Close $16.14 Range $14.15 - $19.05

Q3 2024

Shares 484,300 Value ($000) $7,449 Avg Close $16.68 Range $15.08 - $19.44

Q2 2024

Shares 55,400 Value ($000) $900 Avg Close $16.14 Range $14.55 - $18.63

Q1 2024

Shares 22,000 Value ($000) $407 Avg Close $24.78 Range $17.56 - $31.82

Q4 2023

Shares 69,600 Value ($000) $2,179 Avg Close $23.88 Range $20.31 - $32.59

Q3 2023

Shares 18,700 Value ($000) $390 Avg Close $27.16 Range $20.54 - $33.99

Q2 2023

Shares 170,400 Value ($000) $4,081 Avg Close $22.23 Range $17.71 - $26.04

Q1 2023

Shares 12,300 Value ($000) $231 Avg Close $19.05 Range $15.77 - $21.87

Q2 2022

Shares 16,600 Value ($000) $234 Avg Close $18.68 Range $12.24 - $28.06

Q1 2022

Shares 56,900 Value ($000) $1,378 Avg Close $24.20 Range $20.74 - $27.81

Q1 2021

Shares 189,500 Value ($000) $4,889 Avg Close $44.02 Range $23.35 - $55.85

Q4 2020

Shares 422,600 Value ($000) $22,592 Avg Close $49.64 Range $40.38 - $57.46

Q3 2020

Shares 638,200 Value ($000) $26,326 Avg Close $43.18 Range $36.33 - $58.72

Q2 2020

Shares 400,100 Value ($000) $19,393 Avg Close $48.00 Range $38.45 - $53.75

Q1 2020

Shares 61,700 Value ($000) $2,607 Avg Close $41.20 Range $30.02 - $47.99

Q4 2019

Shares 104,800 Value ($000) $4,483 Avg Close $43.50 Range $35.35 - $53.70

Q3 2019

Shares 107,300 Value ($000) $3,862 Avg Close $30.32 Range $21.56 - $44.85

Q2 2019

Shares 71,300 Value ($000) $1,906 Avg Close $25.54 Range $22.45 - $28.67

Q1 2019

Shares 73,100 Value ($000) $1,963 Avg Close $23.35 Range $15.73 - $28.12

Q4 2018

Shares 54,500 Value ($000) $881 Avg Close $19.42 Range $14.01 - $23.55

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	370,200	$9,888	$23.90	$19.69 - $28.35
Q3 2025	98,400	$2,100	$23.65	$20.02 - $26.65
Q2 2025	194,900	$4,204	$18.59	$13.40 - $25.23
Q1 2025	967,500	$16,070	$18.17	$16.28 - $20.68
Q4 2024	1,263,200	$23,180	$16.14	$14.15 - $19.05
Q3 2024	484,300	$7,449	$16.68	$15.08 - $19.44
Q2 2024	55,400	$900	$16.14	$14.55 - $18.63
Q1 2024	22,000	$407	$24.78	$17.56 - $31.82
Q4 2023	69,600	$2,179	$23.88	$20.31 - $32.59
Q3 2023	18,700	$390	$27.16	$20.54 - $33.99
Q2 2023	170,400	$4,081	$22.23	$17.71 - $26.04
Q1 2023	12,300	$231	$19.05	$15.77 - $21.87
Q2 2022	16,600	$234	$18.68	$12.24 - $28.06
Q1 2022	56,900	$1,378	$24.20	$20.74 - $27.81
Q1 2021	189,500	$4,889	$44.02	$23.35 - $55.85
Q4 2020	422,600	$22,592	$49.64	$40.38 - $57.46
Q3 2020	638,200	$26,326	$43.18	$36.33 - $58.72
Q2 2020	400,100	$19,393	$48.00	$38.45 - $53.75
Q1 2020	61,700	$2,607	$41.20	$30.02 - $47.99
Q4 2019	104,800	$4,483	$43.50	$35.35 - $53.70
Q3 2019	107,300	$3,862	$30.32	$21.56 - $44.85
Q2 2019	71,300	$1,906	$25.54	$22.45 - $28.67
Q1 2019	73,100	$1,963	$23.35	$15.73 - $28.12
Q4 2018	54,500	$881	$19.42	$14.01 - $23.55