ACHILLION PHARMACEUTICALS IN

CUSIP: 00448Q201 Class: COM

ADAGE CAPITAL PARTNERS GP, L.L.C.'s Holding History (CIK: 0001165408)

Note: Option positions (PUT/CALL) are excluded.

Q3 2015
Shares 800,700 Value ($000) $5,533 Avg Close — Range —
Q2 2015
Shares 3,018,430 Value ($000) $26,743 Avg Close — Range —
Q1 2015
Shares 2,843,430 Value ($000) $28,036 Avg Close — Range —
Q4 2014
Shares 1,643,430 Value ($000) $20,132 Avg Close — Range —
Q1 2014
Shares 870,009 Value ($000) $2,862 Avg Close — Range —
Q3 2013
Shares 628,267 Value ($000) $1,897 Avg Close — Range —
Q2 2013
Shares 1,415,467 Value ($000) $11,579 Avg Close — Range —
Q1 2013
Shares 1,272,067 Value ($000) $11,131 Avg Close — Range —