ACHILLION PHARMACEUTICALS IN

CUSIP: 00448Q201 Class: COM

TWO SIGMA INVESTMENTS, LP's Holding History (CIK: 0001179392)

Note: Option positions (PUT/CALL) are excluded.

Q4 2019
Shares 344,781 Value ($000) $2,079 Avg Close — Range —
Q3 2019
Shares 676,688 Value ($000) $2,436 Avg Close — Range —
Q2 2019
Shares 532,031 Value ($000) $1,426 Avg Close — Range —
Q1 2019
Shares 355,737 Value ($000) $1,053 Avg Close — Range —
Q4 2018
Shares 1,171,696 Value ($000) $1,863 Avg Close — Range —
Q3 2018
Shares 48,703 Value ($000) $179 Avg Close — Range —
Q4 2017
Shares 1,107,595 Value ($000) $3,190 Avg Close — Range —
Q4 2016
Shares 383,676 Value ($000) $1,585 Avg Close — Range —
Q3 2016
Shares 125,387 Value ($000) $1,016 Avg Close — Range —
Q2 2016
Shares 12,453 Value ($000) $97 Avg Close — Range —
Q1 2016
Shares 19,900 Value ($000) $154 Avg Close — Range —
Q4 2015
Shares 37,500 Value ($000) $405 Avg Close — Range —
Q3 2014
Shares 546,672 Value ($000) $5,456 Avg Close — Range —
Q2 2014
Shares 90,449 Value ($000) $685 Avg Close — Range —