ACHILLION PHARMACEUTICALS IN

CUSIP: 00448Q201 Class: COM

TWO SIGMA ADVISERS, LP's Holding History (CIK: 0001478735)

Note: Option positions (PUT/CALL) are excluded.

Q4 2019
Shares 583,428 Value ($000) $3,518 Avg Close — Range —
Q3 2019
Shares 571,428 Value ($000) $2,057 Avg Close — Range —
Q2 2019
Shares 385,828 Value ($000) $1,034 Avg Close — Range —
Q1 2019
Shares 298,728 Value ($000) $884 Avg Close — Range —
Q4 2018
Shares 307,828 Value ($000) $489 Avg Close — Range —
Q3 2018
Shares 14,013 Value ($000) $52 Avg Close — Range —
Q2 2018
Shares 34,413 Value ($000) $97 Avg Close — Range —
Q4 2017
Shares 108,913 Value ($000) $314 Avg Close — Range —
Q4 2016
Shares 58,185 Value ($000) $240 Avg Close — Range —
Q3 2016
Shares 31,828 Value ($000) $258 Avg Close — Range —
Q2 2016
Shares 23,628 Value ($000) $184 Avg Close — Range —
Q1 2016
Shares 37,400 Value ($000) $289 Avg Close — Range —
Q4 2015
Shares 57,000 Value ($000) $615 Avg Close — Range —
Q3 2014
Shares 94,028 Value ($000) $938 Avg Close — Range —
Q2 2014
Shares 72,500 Value ($000) $549 Avg Close — Range —