ACRIVON THERAPEUTICS INC

Ticker: ACRV CUSIP: 004890109 Class: Common Stock

TWO SIGMA INVESTMENTS, LP's Holding History (CIK: 0001179392)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 585,069 Value ($000) $1,410 Avg Close $2.17 Range $1.69 - $2.73

Q3 2025

Shares 319,205 Value ($000) $578 Avg Close $1.41 Range $1.15 - $2.67

Q2 2025

Shares 181,172 Value ($000) $216 Avg Close $1.37 Range $1.05 - $2.19

Q4 2022

Shares 21,534 Value ($000) $248 Avg Close $12.69 Range $10.90 - $20.70

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	585,069	$1,410	$2.17	$1.69 - $2.73
Q3 2025	319,205	$578	$1.41	$1.15 - $2.67
Q2 2025	181,172	$216	$1.37	$1.05 - $2.19
Q4 2022	21,534	$248	$12.69	$10.90 - $20.70