ACURA PHARMACEUTICALS INC

CUSIP: 00509L703 Class: CMN

MANUFACTURERS LIFE INSURANCE COMPANY, THE's Holding History (CIK: 0000928047)

Note: Option positions (PUT/CALL) are excluded.

Q2 2015
Shares 1,950 Value ($000) $2 Avg Close — Range —
Q1 2015
Shares 1,950 Value ($000) $2 Avg Close — Range —
Q4 2014
Shares 1,950 Value ($000) $1 Avg Close — Range —
Q3 2014
Shares 1,950 Value ($000) $2 Avg Close — Range —
Q2 2014
Shares 1,950 Value ($000) $2 Avg Close — Range —
Q1 2014
Shares 1,950 Value ($000) $3 Avg Close — Range —
Q4 2013
Shares 1,950 Value ($000) $3 Avg Close — Range —
Q3 2013
Shares 1,950 Value ($000) $4 Avg Close — Range —
Q2 2013
Shares 1,950 Value ($000) $4 Avg Close — Range —