ADAMAS PHARMACEUTICALS INC

CUSIP: 00548A106 Class: COM

TWO SIGMA INVESTMENTS, LP's Holding History (CIK: 0001179392)

Note: Option positions (PUT/CALL) are excluded.

Q3 2021
Shares 331,243 Value ($000) $1,626 Avg Close — Range —
Q2 2021
Shares 578,159 Value ($000) $3,053 Avg Close — Range —
Q1 2021
Shares 427,458 Value ($000) $2,052 Avg Close — Range —
Q4 2020
Shares 174,534 Value ($000) $756 Avg Close — Range —
Q3 2020
Shares 139,059 Value ($000) $573 Avg Close — Range —
Q3 2019
Shares 58,231 Value ($000) $298 Avg Close — Range —
Q2 2019
Shares 27,720 Value ($000) $172 Avg Close — Range —
Q1 2019
Shares 41,711 Value ($000) $297 Avg Close — Range —
Q4 2018
Shares 78,189 Value ($000) $668 Avg Close — Range —
Q4 2015
Shares 19,876 Value ($000) $563 Avg Close — Range —
Q2 2015
Shares 29,800 Value ($000) $781 Avg Close — Range —