AEGLEA BIOTHERAPEUTICS INC

CUSIP: 00773J103 Class: COM

MANUFACTURERS LIFE INSURANCE COMPANY, THE's Holding History (CIK: 0000928047)

Note: Option positions (PUT/CALL) are excluded.

Q1 2022
Shares 11,679 Value ($000) $27 Avg Close — Range —
Q4 2021
Shares 20,139 Value ($000) $96 Avg Close — Range —
Q3 2021
Shares 25,323 Value ($000) $201 Avg Close — Range —
Q2 2021
Shares 26,523 Value ($000) $185 Avg Close — Range —
Q1 2021
Shares 29,097 Value ($000) $230 Avg Close — Range —
Q4 2020
Shares 29,124 Value ($000) $229 Avg Close — Range —
Q3 2020
Shares 25,754 Value ($000) $183 Avg Close — Range —
Q2 2020
Shares 25,754 Value ($000) $236 Avg Close — Range —
Q1 2020
Shares 18,583 Value ($000) $87 Avg Close — Range —
Q4 2019
Shares 17,398 Value ($000) $133 Avg Close — Range —
Q3 2019
Shares 19,622 Value ($000) $150 Avg Close — Range —
Q2 2019
Shares 19,526 Value ($000) $134 Avg Close — Range —
Q2 2018
Shares 13,755 Value ($000) $145 Avg Close — Range —