AEGLEA BIOTHERAPEUTICS INC

CUSIP: 00773J103 Class: COM

TWO SIGMA ADVISERS, LP's Holding History (CIK: 0001478735)

Note: Option positions (PUT/CALL) are excluded.

Q1 2023
Shares 210,800 Value ($000) $61 Avg Close — Range —
Q4 2022
Shares 272,800 Value ($000) $123 Avg Close — Range —
Q3 2022
Shares 409,900 Value ($000) $216 Avg Close — Range —
Q2 2022
Shares 231,700 Value ($000) $117 Avg Close — Range —
Q1 2022
Shares 161,300 Value ($000) $371 Avg Close — Range —
Q4 2021
Shares 38,200 Value ($000) $181 Avg Close — Range —
Q1 2021
Shares 33,800 Value ($000) $268 Avg Close — Range —
Q4 2020
Shares 63,400 Value ($000) $499 Avg Close — Range —
Q3 2020
Shares 57,200 Value ($000) $406 Avg Close — Range —
Q2 2020
Shares 42,700 Value ($000) $395 Avg Close — Range —
Q1 2020
Shares 33,100 Value ($000) $154 Avg Close — Range —
Q4 2019
Shares 32,900 Value ($000) $251 Avg Close — Range —
Q3 2019
Shares 15,900 Value ($000) $122 Avg Close — Range —
Q2 2019
Shares 13,800 Value ($000) $95 Avg Close — Range —