ADVERUM BIOTECHNOLOGIES INC

CUSIP: 00773U108 Class: Common Stock

TWO SIGMA INVESTMENTS, LP's Holding History (CIK: 0001179392)

Note: Option positions (PUT/CALL) are excluded.

Q4 2023
Shares 446,396 Value ($000) $336 Avg Close — Range —
Q3 2023
Shares 518,035 Value ($000) $777 Avg Close — Range —
Q2 2023
Shares 485,340 Value ($000) $772 Avg Close — Range —
Q1 2023
Shares 621,122 Value ($000) $446 Avg Close — Range —
Q4 2022
Shares 707,647 Value ($000) $410 Avg Close — Range —
Q3 2022
Shares 1,048,063 Value ($000) $996 Avg Close — Range —
Q2 2022
Shares 1,164,562 Value ($000) $1,397 Avg Close — Range —
Q1 2022
Shares 1,568,597 Value ($000) $2,055 Avg Close — Range —
Q4 2021
Shares 1,766,277 Value ($000) $3,109 Avg Close — Range —
Q3 2021
Shares 1,870,697 Value ($000) $4,059 Avg Close — Range —
Q2 2021
Shares 1,520,734 Value ($000) $5,323 Avg Close — Range —
Q1 2021
Shares 681,934 Value ($000) $6,724 Avg Close — Range —
Q4 2020
Shares 677,630 Value ($000) $7,346 Avg Close — Range —
Q3 2020
Shares 1,062,791 Value ($000) $10,947 Avg Close — Range —
Q2 2020
Shares 15,249 Value ($000) $318 Avg Close — Range —
Q3 2019
Shares 113,633 Value ($000) $619 Avg Close — Range —
Q1 2019
Shares 74,728 Value ($000) $392 Avg Close — Range —
Q4 2018
Shares 272,789 Value ($000) $859 Avg Close — Range —
Q3 2018
Shares 185,364 Value ($000) $1,121 Avg Close — Range —
Q1 2018
Shares 17,223 Value ($000) $100 Avg Close — Range —
Q4 2017
Shares 337,956 Value ($000) $1,183 Avg Close — Range —
Q3 2017
Shares 75,012 Value ($000) $274 Avg Close — Range —
Q2 2017
Shares 62,325 Value ($000) $156 Avg Close — Range —