ADVERUM BIOTECHNOLOGIES INC

CUSIP: 00773U108 Class: Common Stock

TWIN FOCUS CAPITAL PARTNERS, LLC's Holding History (CIK: 0001387761)

Note: Option positions (PUT/CALL) are excluded.

Q3 2022
Shares 100,000 Value ($000) $95 Avg Close — Range —
Q2 2022
Shares 100,000 Value ($000) $120 Avg Close — Range —
Q1 2022
Shares 100,000 Value ($000) $131 Avg Close — Range —
Q4 2021
Shares 100,000 Value ($000) $176 Avg Close — Range —
Q3 2021
Shares 100,000 Value ($000) $217 Avg Close — Range —
Q2 2021
Shares 100,000 Value ($000) $350 Avg Close — Range —
Q1 2021
Shares 100,000 Value ($000) $986 Avg Close — Range —