ADVERUM BIOTECHNOLOGIES INC

CUSIP: 00773U207 Class: Common Stock

TWO SIGMA INVESTMENTS, LP's Holding History (CIK: 0001179392)

Note: Option positions (PUT/CALL) are excluded.

Q3 2025
Shares 88,670 Value ($000) $402 Avg Close — Range —
Q2 2025
Shares 18,757 Value ($000) $40 Avg Close — Range —
Q3 2024
Shares 27,499 Value ($000) $193 Avg Close — Range —
Q2 2024
Shares 77,345 Value ($000) $531 Avg Close — Range —
Q1 2024
Shares 11,842 Value ($000) $167 Avg Close — Range —