AILERON THERAPEUTICS INC

CUSIP: 00887A105 Class: Stock

TWO SIGMA ADVISERS, LP's Holding History (CIK: 0001478735)

Note: Option positions (PUT/CALL) are excluded.

Q4 2021
Shares 11,300 Value ($000) $6 Avg Close — Range —
Q2 2021
Shares 124,800 Value ($000) $156 Avg Close — Range —
Q1 2021
Shares 184,400 Value ($000) $264 Avg Close — Range —