AKEBIA THERAPEUTICS INC

Ticker: AKBA CUSIP: 00972D105 Class: COM

D. E. Shaw & Co., Inc.'s Holding History (CIK: 0001009207)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 15,522 Value ($000) $25 Avg Close $2.09 Range $1.45 - $3.20

Q3 2025

Shares 39,126 Value ($000) $107 Avg Close $3.33 Range $2.66 - $4.08

Q2 2025

Shares 219,089 Value ($000) $797 Avg Close $2.75 Range $1.52 - $4.08

Q1 2025

Shares 73,161 Value ($000) $140 Avg Close $2.04 Range $1.52 - $2.89

Q4 2024

Shares 82,661 Value ($000) $157 Avg Close $1.74 Range $1.24 - $2.17

Q3 2024

Shares 82,961 Value ($000) $110 Avg Close $1.34 Range $0.91 - $1.58

Q1 2022

Shares 22,547 Value ($000) $16 Avg Close $2.14 Range $0.67 - $2.93

Q4 2021

Shares 14,393 Value ($000) $33 Avg Close $2.73 Range $2.20 - $3.35

Q4 2020

Shares 416,583 Value ($000) $1,166 Avg Close $2.92 Range $2.09 - $4.18

Q3 2020

Shares 2,030,370 Value ($000) $5,096 Avg Close $8.78 Range $2.34 - $13.71

Q2 2020

Shares 2,321,807 Value ($000) $31,530 Avg Close $10.35 Range $6.37 - $13.68

Q1 2020

Shares 1,311,965 Value ($000) $9,945 Avg Close $7.78 Range $3.81 - $10.53

Q4 2019

Shares 787,631 Value ($000) $4,978 Avg Close $4.75 Range $2.99 - $6.96

Q3 2019

Shares 409,043 Value ($000) $1,603 Avg Close $4.29 Range $3.50 - $5.77

Q2 2019

Shares 526,592 Value ($000) $2,549 Avg Close $5.69 Range $4.09 - $8.33

Q1 2019

Shares 351,787 Value ($000) $2,881 Avg Close $6.86 Range $5.22 - $9.30

Q4 2018

Shares 417,178 Value ($000) $2,307 Avg Close $7.83 Range $5.20 - $10.45

Q3 2018

Shares 104,971 Value ($000) $927 Avg Close $8.94 Range $7.32 - $10.73

Q2 2018

Shares 79,575 Value ($000) $794 Avg Close $10.01 Range $7.90 - $11.60

Q1 2018

Shares 31,714 Value ($000) $302 Avg Close $13.99 Range $9.29 - $15.86

Q4 2017

Shares 51,349 Value ($000) $764 Avg Close $16.58 Range $14.07 - $20.25

Q3 2017

Shares 99,937 Value ($000) $1,966 Avg Close $15.37 Range $12.78 - $19.73

Q2 2017

Shares 20,478 Value ($000) $294 Avg Close $12.68 Range $8.69 - $16.54

Q4 2016

Shares 14,477 Value ($000) $151 Avg Close $8.61 Range $7.16 - $11.07

Q3 2016

Shares 23,359 Value ($000) $211 Avg Close $8.50 Range $7.31 - $9.38

Q2 2016

Shares 24,485 Value ($000) $183 Avg Close $8.73 Range $7.00 - $9.99

Q1 2016

Shares 27,700 Value ($000) $250 Avg Close $8.11 Range $7.02 - $12.74

Q4 2014

Shares 14,584 Value ($000) $170 Avg Close $14.34 Range $8.60 - $21.75

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	15,522	$25	$2.09	$1.45 - $3.20
Q3 2025	39,126	$107	$3.33	$2.66 - $4.08
Q2 2025	219,089	$797	$2.75	$1.52 - $4.08
Q1 2025	73,161	$140	$2.04	$1.52 - $2.89
Q4 2024	82,661	$157	$1.74	$1.24 - $2.17
Q3 2024	82,961	$110	$1.34	$0.91 - $1.58
Q1 2022	22,547	$16	$2.14	$0.67 - $2.93
Q4 2021	14,393	$33	$2.73	$2.20 - $3.35
Q4 2020	416,583	$1,166	$2.92	$2.09 - $4.18
Q3 2020	2,030,370	$5,096	$8.78	$2.34 - $13.71
Q2 2020	2,321,807	$31,530	$10.35	$6.37 - $13.68
Q1 2020	1,311,965	$9,945	$7.78	$3.81 - $10.53
Q4 2019	787,631	$4,978	$4.75	$2.99 - $6.96
Q3 2019	409,043	$1,603	$4.29	$3.50 - $5.77
Q2 2019	526,592	$2,549	$5.69	$4.09 - $8.33
Q1 2019	351,787	$2,881	$6.86	$5.22 - $9.30
Q4 2018	417,178	$2,307	$7.83	$5.20 - $10.45
Q3 2018	104,971	$927	$8.94	$7.32 - $10.73
Q2 2018	79,575	$794	$10.01	$7.90 - $11.60
Q1 2018	31,714	$302	$13.99	$9.29 - $15.86
Q4 2017	51,349	$764	$16.58	$14.07 - $20.25
Q3 2017	99,937	$1,966	$15.37	$12.78 - $19.73
Q2 2017	20,478	$294	$12.68	$8.69 - $16.54
Q4 2016	14,477	$151	$8.61	$7.16 - $11.07
Q3 2016	23,359	$211	$8.50	$7.31 - $9.38
Q2 2016	24,485	$183	$8.73	$7.00 - $9.99
Q1 2016	27,700	$250	$8.11	$7.02 - $12.74
Q4 2014	14,584	$170	$14.34	$8.60 - $21.75