AKEBIA THERAPEUTICS INC

Ticker: AKBA CUSIP: 00972D105 Class: COM

Brevan Howard Capital Management LP's Holding History (CIK: 0001512857)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 236,631 Value ($000) $381 Avg Close $2.09 Range $1.45 - $3.20

Q3 2025

Shares 78,121 Value ($000) $213 Avg Close $3.33 Range $2.66 - $4.08

Q2 2025

Shares 17,148 Value ($000) $62 Avg Close $2.75 Range $1.52 - $4.08

Q1 2024

Shares 81,676 Value ($000) $149 Avg Close $1.60 Range $1.21 - $2.48

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	236,631	$381	$2.09	$1.45 - $3.20
Q3 2025	78,121	$213	$3.33	$2.66 - $4.08
Q2 2025	17,148	$62	$2.75	$1.52 - $4.08
Q1 2024	81,676	$149	$1.60	$1.21 - $2.48