AKCEA THERAPEUTICS INC

CUSIP: 00972L107 Class: COM

MANUFACTURERS LIFE INSURANCE COMPANY, THE's Holding History (CIK: 0000928047)

Note: Option positions (PUT/CALL) are excluded.

Q3 2020
Shares 11,870 Value ($000) $215 Avg Close — Range —
Q2 2020
Shares 11,870 Value ($000) $170 Avg Close — Range —
Q1 2020
Shares 10,402 Value ($000) $149 Avg Close — Range —
Q3 2019
Shares 10,179 Value ($000) $165 Avg Close — Range —
Q2 2019
Shares 10,112 Value ($000) $237 Avg Close — Range —
Q3 2018
Shares 6,291 Value ($000) $220 Avg Close — Range —
Q2 2018
Shares 11,687 Value ($000) $277 Avg Close — Range —
Q1 2018
Shares 13,015 Value ($000) $333 Avg Close — Range —
Q4 2017
Shares 13,238 Value ($000) $230 Avg Close — Range —
Q3 2017
Shares 11,115 Value ($000) $308 Avg Close — Range —