AKCEA THERAPEUTICS INC

CUSIP: 00972L107 Class: COM

Swiss National Bank's Holding History (CIK: 0001582202)

Note: Option positions (PUT/CALL) are excluded.

Q3 2020
Shares 45,100 Value ($000) $818 Avg Close — Range —
Q2 2020
Shares 45,100 Value ($000) $618 Avg Close — Range —
Q1 2020
Shares 36,400 Value ($000) $521 Avg Close — Range —
Q4 2019
Shares 35,600 Value ($000) $603 Avg Close — Range —
Q3 2019
Shares 34,800 Value ($000) $536 Avg Close — Range —
Q2 2019
Shares 33,300 Value ($000) $781 Avg Close — Range —
Q1 2019
Shares 32,500 Value ($000) $921 Avg Close — Range —
Q4 2018
Shares 30,300 Value ($000) $913 Avg Close — Range —
Q3 2018
Shares 28,300 Value ($000) $991 Avg Close — Range —
Q2 2018
Shares 28,300 Value ($000) $671 Avg Close — Range —
Q1 2018
Shares 28,300 Value ($000) $725 Avg Close — Range —
Q4 2017
Shares 28,300 Value ($000) $491 Avg Close — Range —