AKOUOS INC

CUSIP: 00973J101 Class: COM

ADAGE CAPITAL PARTNERS GP, L.L.C.'s Holding History (CIK: 0001165408)

Note: Option positions (PUT/CALL) are excluded.

Q1 2021
Shares 222,418 Value ($000) $3,085 Avg Close — Range —
Q4 2020
Shares 405,000 Value ($000) $8,031 Avg Close — Range —
Q3 2020
Shares 469,000 Value ($000) $10,726 Avg Close — Range —
Q2 2020
Shares 540,000 Value ($000) $12,150 Avg Close — Range —