ALNYLAM PHARMACEUTICALS INC

Ticker: ALNY CUSIP: 02043Q107 Class: EQTY

BARCLAYS PLC's Holding History (CIK: 0000312069)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 222,561 Value ($000) $88,501 Avg Close $442.56 Range $387.03 - $495.55

Q3 2025

Shares 105,185 Value ($000) $28,929 Avg Close $407.20 Range $309.57 - $484.21

Q2 2025

Shares 94,058 Value ($000) $30,671 Avg Close $276.71 Range $205.87 - $327.21

Q1 2025

Shares 95,719 Value ($000) $25,846 Avg Close $257.00 Range $230.79 - $300.90

Q4 2024

Shares 103,847 Value ($000) $24,436 Avg Close $262.99 Range $229.86 - $304.39

Q3 2024

Shares 105,185 Value ($000) $29 Avg Close $260.36 Range $231.01 - $287.55

Q2 2024

Shares 131,265 Value ($000) $31,897 Avg Close $157.87 Range $141.98 - $252.87

Q1 2024

Shares 193,972 Value ($000) $28,989 Avg Close $166.82 Range $143.52 - $199.38

Q4 2023

Shares 142,000 Value ($000) $27,180 Avg Close $170.34 Range $148.10 - $198.00

Q3 2023

Shares 162,195 Value ($000) $28,725 Avg Close $191.12 Range $168.65 - $218.88

Q2 2023

Shares 210,145 Value ($000) $40 Avg Close $198.26 Range $183.00 - $212.47

Q1 2023

Shares 141,595 Value ($000) $28 Avg Close $210.20 Range $179.19 - $242.39

Q4 2022

Shares 162,134 Value ($000) $39 Avg Close $213.29 Range $181.65 - $242.97

Q3 2022

Shares 141,354 Value ($000) $28,292 Avg Close $190.74 Range $135.46 - $236.80

Q2 2022

Shares 126,121 Value ($000) $18,395 Avg Close $141.87 Range $117.58 - $180.35

Q1 2022

Shares 79,598 Value ($000) $12,997 Avg Close $152.35 Range $125.00 - $174.66

Q4 2021

Shares 81,965 Value ($000) $13,899 Avg Close $185.86 Range $154.82 - $212.00

Q3 2021

Shares 97,475 Value ($000) $18,403 Avg Close $187.58 Range $166.16 - $209.73

Q2 2021

Shares 103,026 Value ($000) $17,465 Avg Close $146.46 Range $125.08 - $177.53

Q1 2021

Shares 77,865 Value ($000) $10,995 Avg Close $150.49 Range $124.00 - $178.41

Q4 2020

Shares 62,975 Value ($000) $8,185 Avg Close $133.53 Range $119.29 - $148.76

Q3 2020

Shares 94,495 Value ($000) $13,759 Avg Close $142.10 Range $119.67 - $167.33

Q2 2020

Shares 116,188 Value ($000) $17,208 Avg Close $134.81 Range $98.01 - $158.37

Q1 2020

Shares 102,715 Value ($000) $11,182 Avg Close $115.43 Range $84.97 - $134.51

Q4 2019

Shares 61,158 Value ($000) $7,044 Avg Close $99.70 Range $73.32 - $125.72

Q3 2019

Shares 100,887 Value ($000) $8,114 Avg Close $79.11 Range $69.11 - $88.00

Q2 2019

Shares 65,893 Value ($000) $4,780 Avg Close $76.72 Range $65.81 - $96.08

Q1 2019

Shares 50,123 Value ($000) $4,683 Avg Close $83.64 Range $70.29 - $93.95

Q4 2018

Shares 73,566 Value ($000) $5,364 Avg Close $76.92 Range $60.27 - $90.00

Q3 2018

Shares 69,674 Value ($000) $6,098 Avg Close $100.59 Range $86.95 - $124.22

Q2 2018

Shares 50,112 Value ($000) $4,936 Avg Close $99.19 Range $87.35 - $118.71

Q1 2018

Shares 17,018 Value ($000) $2,026 Avg Close $128.92 Range $108.13 - $153.99

Q4 2017

Shares 85,544 Value ($000) $10,869 Avg Close $125.65 Range $111.25 - $147.63

Q3 2017

Shares 11,447 Value ($000) $1,344 Avg Close $85.36 Range $70.76 - $119.02

Q2 2017

Shares 54,322 Value ($000) $4,332 Avg Close $63.91 Range $46.90 - $86.92

Q1 2017

Shares 50,633 Value ($000) $2,595 Avg Close $46.22 Range $35.98 - $60.41

Q4 2016

Shares 51,172 Value ($000) $1,917 Avg Close $41.87 Range $31.38 - $71.67

Q3 2016

Shares 17,887 Value ($000) $1,213 Avg Close $70.55 Range $53.56 - $80.11

Q2 2016

Shares 9,502 Value ($000) $527 Avg Close $63.00 Range $49.96 - $75.08

Q1 2016

Shares 28,236 Value ($000) $1,752 Avg Close $66.49 Range $51.51 - $98.00

Q4 2015

Shares 12,967 Value ($000) $1,218 Avg Close $92.72 Range $71.14 - $110.75

Q3 2015

Shares 39,133 Value ($000) $3,131 Avg Close $111.10 Range $76.46 - $137.89

Q2 2015

Shares 12,484 Value ($000) $1,486 Avg Close $119.50 Range $98.63 - $140.00

Q1 2015

Shares 8,867 Value ($000) $922 Avg Close $101.34 Range $82.06 - $121.93

Q4 2014

Shares 528 Value ($000) $51 Avg Close $92.65 Range $72.80 - $111.49

Q3 2014

Shares 33,359 Value ($000) $2,602 Avg Close $64.51 Range $51.93 - $79.88

Q2 2014

Shares 61,821 Value ($000) $3,894 Avg Close $59.44 Range $47.03 - $71.40

Q1 2014

Shares 9,866 Value ($000) $661 Avg Close $77.42 Range $60.24 - $112.57

Q4 2013

Shares 27,965 Value ($000) $1,788 Avg Close $59.65 Range $48.16 - $67.97

Q3 2013

Shares 7,978 Value ($000) $510 Avg Close $49.85 Range $31.75 - $65.83

Q2 2013

Shares 43,212 Value ($000) $1,340 Avg Close $26.61 Range $21.60 - $31.79

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	222,561	$88,501	$442.56	$387.03 - $495.55
Q3 2025	105,185	$28,929	$407.20	$309.57 - $484.21
Q2 2025	94,058	$30,671	$276.71	$205.87 - $327.21
Q1 2025	95,719	$25,846	$257.00	$230.79 - $300.90
Q4 2024	103,847	$24,436	$262.99	$229.86 - $304.39
Q3 2024	105,185	$29	$260.36	$231.01 - $287.55
Q2 2024	131,265	$31,897	$157.87	$141.98 - $252.87
Q1 2024	193,972	$28,989	$166.82	$143.52 - $199.38
Q4 2023	142,000	$27,180	$170.34	$148.10 - $198.00
Q3 2023	162,195	$28,725	$191.12	$168.65 - $218.88
Q2 2023	210,145	$40	$198.26	$183.00 - $212.47
Q1 2023	141,595	$28	$210.20	$179.19 - $242.39
Q4 2022	162,134	$39	$213.29	$181.65 - $242.97
Q3 2022	141,354	$28,292	$190.74	$135.46 - $236.80
Q2 2022	126,121	$18,395	$141.87	$117.58 - $180.35
Q1 2022	79,598	$12,997	$152.35	$125.00 - $174.66
Q4 2021	81,965	$13,899	$185.86	$154.82 - $212.00
Q3 2021	97,475	$18,403	$187.58	$166.16 - $209.73
Q2 2021	103,026	$17,465	$146.46	$125.08 - $177.53
Q1 2021	77,865	$10,995	$150.49	$124.00 - $178.41
Q4 2020	62,975	$8,185	$133.53	$119.29 - $148.76
Q3 2020	94,495	$13,759	$142.10	$119.67 - $167.33
Q2 2020	116,188	$17,208	$134.81	$98.01 - $158.37
Q1 2020	102,715	$11,182	$115.43	$84.97 - $134.51
Q4 2019	61,158	$7,044	$99.70	$73.32 - $125.72
Q3 2019	100,887	$8,114	$79.11	$69.11 - $88.00
Q2 2019	65,893	$4,780	$76.72	$65.81 - $96.08
Q1 2019	50,123	$4,683	$83.64	$70.29 - $93.95
Q4 2018	73,566	$5,364	$76.92	$60.27 - $90.00
Q3 2018	69,674	$6,098	$100.59	$86.95 - $124.22
Q2 2018	50,112	$4,936	$99.19	$87.35 - $118.71
Q1 2018	17,018	$2,026	$128.92	$108.13 - $153.99
Q4 2017	85,544	$10,869	$125.65	$111.25 - $147.63
Q3 2017	11,447	$1,344	$85.36	$70.76 - $119.02
Q2 2017	54,322	$4,332	$63.91	$46.90 - $86.92
Q1 2017	50,633	$2,595	$46.22	$35.98 - $60.41
Q4 2016	51,172	$1,917	$41.87	$31.38 - $71.67
Q3 2016	17,887	$1,213	$70.55	$53.56 - $80.11
Q2 2016	9,502	$527	$63.00	$49.96 - $75.08
Q1 2016	28,236	$1,752	$66.49	$51.51 - $98.00
Q4 2015	12,967	$1,218	$92.72	$71.14 - $110.75
Q3 2015	39,133	$3,131	$111.10	$76.46 - $137.89
Q2 2015	12,484	$1,486	$119.50	$98.63 - $140.00
Q1 2015	8,867	$922	$101.34	$82.06 - $121.93
Q4 2014	528	$51	$92.65	$72.80 - $111.49
Q3 2014	33,359	$2,602	$64.51	$51.93 - $79.88
Q2 2014	61,821	$3,894	$59.44	$47.03 - $71.40
Q1 2014	9,866	$661	$77.42	$60.24 - $112.57
Q4 2013	27,965	$1,788	$59.65	$48.16 - $67.97
Q3 2013	7,978	$510	$49.85	$31.75 - $65.83
Q2 2013	43,212	$1,340	$26.61	$21.60 - $31.79