ALNYLAM PHARMACEUTICALS INC

Ticker: ALNY CUSIP: 02043Q107 Class: EQTY

PUBLIC EMPLOYEES RETIREMENT ASSOCIATION OF COLORADO's Holding History (CIK: 0000315297)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 12,445 Value ($000) $5 Avg Close $442.56 Range $387.03 - $495.55

Q3 2025

Shares 12,445 Value ($000) $6 Avg Close $407.20 Range $309.57 - $484.21

Q2 2025

Shares 12,841 Value ($000) $4 Avg Close $276.71 Range $205.87 - $327.21

Q1 2025

Shares 13,073 Value ($000) $4 Avg Close $257.00 Range $230.79 - $300.90

Q4 2024

Shares 13,073 Value ($000) $3 Avg Close $262.99 Range $229.86 - $304.39

Q3 2024

Shares 13,384 Value ($000) $4 Avg Close $260.36 Range $231.01 - $287.55

Q2 2024

Shares 13,384 Value ($000) $3 Avg Close $157.87 Range $141.98 - $252.87

Q1 2024

Shares 13,875 Value ($000) $2 Avg Close $166.82 Range $143.52 - $199.38

Q4 2023

Shares 14,397 Value ($000) $3 Avg Close $170.34 Range $148.10 - $198.00

Q3 2023

Shares 15,106 Value ($000) $3 Avg Close $191.12 Range $168.65 - $218.88

Q2 2023

Shares 15,690 Value ($000) $3 Avg Close $198.26 Range $183.00 - $212.47

Q1 2023

Shares 15,690 Value ($000) $3 Avg Close $210.20 Range $179.19 - $242.39

Q4 2022

Shares 15,690 Value ($000) $4 Avg Close $213.29 Range $181.65 - $242.97

Q3 2022

Shares 15,690 Value ($000) $3,141 Avg Close $190.74 Range $135.46 - $236.80

Q2 2022

Shares 15,690 Value ($000) $2,288 Avg Close $141.87 Range $117.58 - $180.35

Q1 2022

Shares 15,690 Value ($000) $2,562 Avg Close $152.35 Range $125.00 - $174.66

Q4 2021

Shares 16,463 Value ($000) $2,792 Avg Close $185.86 Range $154.82 - $212.00

Q3 2021

Shares 16,463 Value ($000) $3,108 Avg Close $187.58 Range $166.16 - $209.73

Q2 2021

Shares 16,463 Value ($000) $2,791 Avg Close $146.46 Range $125.08 - $177.53

Q1 2021

Shares 16,463 Value ($000) $2,324 Avg Close $150.49 Range $124.00 - $178.41

Q4 2020

Shares 16,463 Value ($000) $2,140 Avg Close $133.53 Range $119.29 - $148.76

Q3 2020

Shares 16,463 Value ($000) $2,397 Avg Close $142.10 Range $119.67 - $167.33

Q2 2020

Shares 16,463 Value ($000) $2,438 Avg Close $134.81 Range $98.01 - $158.37

Q1 2020

Shares 16,463 Value ($000) $1,792 Avg Close $115.43 Range $84.97 - $134.51

Q4 2019

Shares 13,797 Value ($000) $1,589 Avg Close $99.70 Range $73.32 - $125.72

Q3 2019

Shares 13,797 Value ($000) $1,110 Avg Close $79.11 Range $69.11 - $88.00

Q2 2019

Shares 13,797 Value ($000) $1,001 Avg Close $76.72 Range $65.81 - $96.08

Q1 2019

Shares 13,797 Value ($000) $1,289 Avg Close $83.64 Range $70.29 - $93.95

Q4 2018

Shares 17,055 Value ($000) $1,243 Avg Close $76.92 Range $60.27 - $90.00

Q3 2018

Shares 17,093 Value ($000) $1,496 Avg Close $100.59 Range $86.95 - $124.22

Q2 2018

Shares 17,110 Value ($000) $1,685 Avg Close $99.19 Range $87.35 - $118.71

Q1 2018

Shares 17,099 Value ($000) $2,036 Avg Close $128.92 Range $108.13 - $153.99

Q4 2017

Shares 17,321 Value ($000) $2,201 Avg Close $125.65 Range $111.25 - $147.63

Q3 2017

Shares 16,585 Value ($000) $1,949 Avg Close $85.36 Range $70.76 - $119.02

Q2 2017

Shares 16,759 Value ($000) $1,337 Avg Close $63.91 Range $46.90 - $86.92

Q1 2017

Shares 16,762 Value ($000) $859 Avg Close $46.22 Range $35.98 - $60.41

Q4 2016

Shares 16,792 Value ($000) $629 Avg Close $41.87 Range $31.38 - $71.67

Q3 2016

Shares 16,801 Value ($000) $1,139 Avg Close $70.55 Range $53.56 - $80.11

Q2 2016

Shares 17,829 Value ($000) $989 Avg Close $63.00 Range $49.96 - $75.08

Q1 2016

Shares 17,808 Value ($000) $1,118 Avg Close $66.49 Range $51.51 - $98.00

Q4 2015

Shares 17,831 Value ($000) $1,679 Avg Close $92.72 Range $71.14 - $110.75

Q3 2015

Shares 17,812 Value ($000) $1,431 Avg Close $111.10 Range $76.46 - $137.89

Q2 2015

Shares 17,836 Value ($000) $2,138 Avg Close $119.50 Range $98.63 - $140.00

Q1 2015

Shares 17,808 Value ($000) $1,860 Avg Close $101.34 Range $82.06 - $121.93

Q4 2014

Shares 17,571 Value ($000) $1,704 Avg Close $92.65 Range $72.80 - $111.49

Q3 2014

Shares 17,607 Value ($000) $1,375 Avg Close $64.51 Range $51.93 - $79.88

Q2 2014

Shares 17,627 Value ($000) $1,113 Avg Close $59.44 Range $47.03 - $71.40

Q1 2014

Shares 16,491 Value ($000) $1,107 Avg Close $77.42 Range $60.24 - $112.57

Q4 2013

Shares 16,491 Value ($000) $1,061 Avg Close $59.65 Range $48.16 - $67.97

Q3 2013

Shares 16,491 Value ($000) $1,056 Avg Close $49.85 Range $31.75 - $65.83

Q2 2013

Shares 16,491 Value ($000) $511 Avg Close $26.61 Range $21.60 - $31.79

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	12,445	$5	$442.56	$387.03 - $495.55
Q3 2025	12,445	$6	$407.20	$309.57 - $484.21
Q2 2025	12,841	$4	$276.71	$205.87 - $327.21
Q1 2025	13,073	$4	$257.00	$230.79 - $300.90
Q4 2024	13,073	$3	$262.99	$229.86 - $304.39
Q3 2024	13,384	$4	$260.36	$231.01 - $287.55
Q2 2024	13,384	$3	$157.87	$141.98 - $252.87
Q1 2024	13,875	$2	$166.82	$143.52 - $199.38
Q4 2023	14,397	$3	$170.34	$148.10 - $198.00
Q3 2023	15,106	$3	$191.12	$168.65 - $218.88
Q2 2023	15,690	$3	$198.26	$183.00 - $212.47
Q1 2023	15,690	$3	$210.20	$179.19 - $242.39
Q4 2022	15,690	$4	$213.29	$181.65 - $242.97
Q3 2022	15,690	$3,141	$190.74	$135.46 - $236.80
Q2 2022	15,690	$2,288	$141.87	$117.58 - $180.35
Q1 2022	15,690	$2,562	$152.35	$125.00 - $174.66
Q4 2021	16,463	$2,792	$185.86	$154.82 - $212.00
Q3 2021	16,463	$3,108	$187.58	$166.16 - $209.73
Q2 2021	16,463	$2,791	$146.46	$125.08 - $177.53
Q1 2021	16,463	$2,324	$150.49	$124.00 - $178.41
Q4 2020	16,463	$2,140	$133.53	$119.29 - $148.76
Q3 2020	16,463	$2,397	$142.10	$119.67 - $167.33
Q2 2020	16,463	$2,438	$134.81	$98.01 - $158.37
Q1 2020	16,463	$1,792	$115.43	$84.97 - $134.51
Q4 2019	13,797	$1,589	$99.70	$73.32 - $125.72
Q3 2019	13,797	$1,110	$79.11	$69.11 - $88.00
Q2 2019	13,797	$1,001	$76.72	$65.81 - $96.08
Q1 2019	13,797	$1,289	$83.64	$70.29 - $93.95
Q4 2018	17,055	$1,243	$76.92	$60.27 - $90.00
Q3 2018	17,093	$1,496	$100.59	$86.95 - $124.22
Q2 2018	17,110	$1,685	$99.19	$87.35 - $118.71
Q1 2018	17,099	$2,036	$128.92	$108.13 - $153.99
Q4 2017	17,321	$2,201	$125.65	$111.25 - $147.63
Q3 2017	16,585	$1,949	$85.36	$70.76 - $119.02
Q2 2017	16,759	$1,337	$63.91	$46.90 - $86.92
Q1 2017	16,762	$859	$46.22	$35.98 - $60.41
Q4 2016	16,792	$629	$41.87	$31.38 - $71.67
Q3 2016	16,801	$1,139	$70.55	$53.56 - $80.11
Q2 2016	17,829	$989	$63.00	$49.96 - $75.08
Q1 2016	17,808	$1,118	$66.49	$51.51 - $98.00
Q4 2015	17,831	$1,679	$92.72	$71.14 - $110.75
Q3 2015	17,812	$1,431	$111.10	$76.46 - $137.89
Q2 2015	17,836	$2,138	$119.50	$98.63 - $140.00
Q1 2015	17,808	$1,860	$101.34	$82.06 - $121.93
Q4 2014	17,571	$1,704	$92.65	$72.80 - $111.49
Q3 2014	17,607	$1,375	$64.51	$51.93 - $79.88
Q2 2014	17,627	$1,113	$59.44	$47.03 - $71.40
Q1 2014	16,491	$1,107	$77.42	$60.24 - $112.57
Q4 2013	16,491	$1,061	$59.65	$48.16 - $67.97
Q3 2013	16,491	$1,056	$49.85	$31.75 - $65.83
Q2 2013	16,491	$511	$26.61	$21.60 - $31.79