ALNYLAM PHARMACEUTICALS INC

Ticker: ALNY CUSIP: 02043Q107 Class: EQTY

FRONTIER CAPITAL MANAGEMENT CO LLC's Holding History (CIK: 0000351173)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 48,859 Value ($000) $19,429 Avg Close $442.56 Range $387.03 - $495.55

Q3 2025

Shares 118,878 Value ($000) $54,208 Avg Close $407.20 Range $309.57 - $484.21

Q2 2025

Shares 103,003 Value ($000) $33,588 Avg Close $276.71 Range $205.87 - $327.21

Q1 2025

Shares 102,420 Value ($000) $27,655 Avg Close $257.00 Range $230.79 - $300.90

Q4 2024

Shares 104,718 Value ($000) $24,641 Avg Close $262.99 Range $229.86 - $304.39

Q3 2024

Shares 111,231 Value ($000) $30,592 Avg Close $260.36 Range $231.01 - $287.55

Q2 2024

Shares 168,442 Value ($000) $40,931 Avg Close $157.87 Range $141.98 - $252.87

Q2 2021

Shares 45,822 Value ($000) $7,768 Avg Close $146.46 Range $125.08 - $177.53

Q4 2020

Shares 4,746 Value ($000) $617 Avg Close $133.53 Range $119.29 - $148.76

Q3 2020

Shares 4,746 Value ($000) $691 Avg Close $142.10 Range $119.67 - $167.33

Q2 2020

Shares 4,850 Value ($000) $718 Avg Close $134.81 Range $98.01 - $158.37

Q1 2020

Shares 39,037 Value ($000) $4,249 Avg Close $115.43 Range $84.97 - $134.51

Q4 2019

Shares 51,484 Value ($000) $5,929 Avg Close $99.70 Range $73.32 - $125.72

Q3 2019

Shares 93,369 Value ($000) $7,509 Avg Close $79.11 Range $69.11 - $88.00

Q2 2019

Shares 74,689 Value ($000) $5,419 Avg Close $76.72 Range $65.81 - $96.08

Q1 2019

Shares 68,126 Value ($000) $6,366 Avg Close $83.64 Range $70.29 - $93.95

Q4 2018

Shares 197,869 Value ($000) $14,427 Avg Close $76.92 Range $60.27 - $90.00

Q3 2018

Shares 6,240 Value ($000) $546 Avg Close $100.59 Range $86.95 - $124.22

Q2 2018

Shares 36,200 Value ($000) $3,565 Avg Close $99.19 Range $87.35 - $118.71

Q1 2018

Shares 27,036 Value ($000) $3,220 Avg Close $128.92 Range $108.13 - $153.99

Q4 2017

Shares 33,681 Value ($000) $4,279 Avg Close $125.65 Range $111.25 - $147.63

Q3 2017

Shares 84,501 Value ($000) $9,928 Avg Close $85.36 Range $70.76 - $119.02

Q2 2017

Shares 116,922 Value ($000) $9,326 Avg Close $63.91 Range $46.90 - $86.92

Q1 2017

Shares 196,332 Value ($000) $10,062 Avg Close $46.22 Range $35.98 - $60.41

Q4 2016

Shares 236,935 Value ($000) $8,871 Avg Close $41.87 Range $31.38 - $71.67

Q3 2015

Shares 212,682 Value ($000) $17,091 Avg Close $111.10 Range $76.46 - $137.89

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	48,859	$19,429	$442.56	$387.03 - $495.55
Q3 2025	118,878	$54,208	$407.20	$309.57 - $484.21
Q2 2025	103,003	$33,588	$276.71	$205.87 - $327.21
Q1 2025	102,420	$27,655	$257.00	$230.79 - $300.90
Q4 2024	104,718	$24,641	$262.99	$229.86 - $304.39
Q3 2024	111,231	$30,592	$260.36	$231.01 - $287.55
Q2 2024	168,442	$40,931	$157.87	$141.98 - $252.87
Q2 2021	45,822	$7,768	$146.46	$125.08 - $177.53
Q4 2020	4,746	$617	$133.53	$119.29 - $148.76
Q3 2020	4,746	$691	$142.10	$119.67 - $167.33
Q2 2020	4,850	$718	$134.81	$98.01 - $158.37
Q1 2020	39,037	$4,249	$115.43	$84.97 - $134.51
Q4 2019	51,484	$5,929	$99.70	$73.32 - $125.72
Q3 2019	93,369	$7,509	$79.11	$69.11 - $88.00
Q2 2019	74,689	$5,419	$76.72	$65.81 - $96.08
Q1 2019	68,126	$6,366	$83.64	$70.29 - $93.95
Q4 2018	197,869	$14,427	$76.92	$60.27 - $90.00
Q3 2018	6,240	$546	$100.59	$86.95 - $124.22
Q2 2018	36,200	$3,565	$99.19	$87.35 - $118.71
Q1 2018	27,036	$3,220	$128.92	$108.13 - $153.99
Q4 2017	33,681	$4,279	$125.65	$111.25 - $147.63
Q3 2017	84,501	$9,928	$85.36	$70.76 - $119.02
Q2 2017	116,922	$9,326	$63.91	$46.90 - $86.92
Q1 2017	196,332	$10,062	$46.22	$35.98 - $60.41
Q4 2016	236,935	$8,871	$41.87	$31.38 - $71.67
Q3 2015	212,682	$17,091	$111.10	$76.46 - $137.89