ALNYLAM PHARMACEUTICALS INC

Ticker: ALNY CUSIP: 02043Q107 Class: EQTY

DIMENSIONAL FUND ADVISORS LP's Holding History (CIK: 0000354204)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 301,865 Value ($000) $120,033 Avg Close $442.56 Range $387.03 - $495.55

Q3 2025

Shares 241,934 Value ($000) $110,284 Avg Close $407.20 Range $309.57 - $484.21

Q2 2025

Shares 305,563 Value ($000) $99,633 Avg Close $276.71 Range $205.87 - $327.21

Q1 2025

Shares 309,819 Value ($000) $83,645 Avg Close $257.00 Range $230.79 - $300.90

Q4 2024

Shares 333,661 Value ($000) $78,520 Avg Close $262.99 Range $229.86 - $304.39

Q3 2024

Shares 301,389 Value ($000) $82,885 Avg Close $260.36 Range $231.01 - $287.55

Q2 2024

Shares 266,206 Value ($000) $64,702 Avg Close $157.87 Range $141.98 - $252.87

Q1 2024

Shares 255,179 Value ($000) $38,137 Avg Close $166.82 Range $143.52 - $199.38

Q4 2023

Shares 267,034 Value ($000) $51,126 Avg Close $170.34 Range $148.10 - $198.00

Q3 2023

Shares 251,911 Value ($000) $44,611 Avg Close $191.12 Range $168.65 - $218.88

Q2 2023

Shares 240,990 Value ($000) $45,775 Avg Close $198.26 Range $183.00 - $212.47

Q1 2023

Shares 218,479 Value ($000) $43,762 Avg Close $210.20 Range $179.19 - $242.39

Q4 2022

Shares 194,576 Value ($000) $46 Avg Close $213.29 Range $181.65 - $242.97

Q3 2022

Shares 176,266 Value ($000) $35,290 Avg Close $190.74 Range $135.46 - $236.80

Q2 2022

Shares 173,425 Value ($000) $25,292 Avg Close $141.87 Range $117.58 - $180.35

Q1 2022

Shares 181,271 Value ($000) $29,601 Avg Close $152.35 Range $125.00 - $174.66

Q4 2021

Shares 179,160 Value ($000) $30,383 Avg Close $185.86 Range $154.82 - $212.00

Q3 2021

Shares 187,263 Value ($000) $35,351 Avg Close $187.58 Range $166.16 - $209.73

Q2 2021

Shares 204,999 Value ($000) $34,747 Avg Close $146.46 Range $125.08 - $177.53

Q1 2021

Shares 227,702 Value ($000) $32,152 Avg Close $150.49 Range $124.00 - $178.41

Q4 2020

Shares 235,001 Value ($000) $30,545 Avg Close $133.53 Range $119.29 - $148.76

Q3 2020

Shares 238,021 Value ($000) $34,654 Avg Close $142.10 Range $119.67 - $167.33

Q2 2020

Shares 246,330 Value ($000) $36,483 Avg Close $134.81 Range $98.01 - $158.37

Q1 2020

Shares 265,758 Value ($000) $28,926 Avg Close $115.43 Range $84.97 - $134.51

Q4 2019

Shares 261,245 Value ($000) $30,087 Avg Close $99.70 Range $73.32 - $125.72

Q3 2019

Shares 258,967 Value ($000) $20,828 Avg Close $79.11 Range $69.11 - $88.00

Q2 2019

Shares 251,258 Value ($000) $18,229 Avg Close $76.72 Range $65.81 - $96.08

Q1 2019

Shares 224,470 Value ($000) $20,972 Avg Close $83.64 Range $70.29 - $93.95

Q4 2018

Shares 225,148 Value ($000) $16,412 Avg Close $76.92 Range $60.27 - $90.00

Q3 2018

Shares 158,895 Value ($000) $13,910 Avg Close $100.59 Range $86.95 - $124.22

Q2 2018

Shares 161,942 Value ($000) $15,948 Avg Close $99.19 Range $87.35 - $118.71

Q1 2018

Shares 167,072 Value ($000) $19,898 Avg Close $128.92 Range $108.13 - $153.99

Q4 2017

Shares 173,757 Value ($000) $22,081 Avg Close $125.65 Range $111.25 - $147.63

Q3 2017

Shares 180,058 Value ($000) $21,156 Avg Close $85.36 Range $70.76 - $119.02

Q2 2017

Shares 179,429 Value ($000) $14,311 Avg Close $63.91 Range $46.90 - $86.92

Q1 2017

Shares 112,778 Value ($000) $5,780 Avg Close $46.22 Range $35.98 - $60.41

Q4 2016

Shares 111,350 Value ($000) $4,170 Avg Close $41.87 Range $31.38 - $71.67

Q3 2016

Shares 110,655 Value ($000) $7,503 Avg Close $70.55 Range $53.56 - $80.11

Q2 2016

Shares 101,569 Value ($000) $5,636 Avg Close $63.00 Range $49.96 - $75.08

Q1 2016

Shares 102,430 Value ($000) $6,426 Avg Close $66.49 Range $51.51 - $98.00

Q4 2015

Shares 99,578 Value ($000) $9,375 Avg Close $92.72 Range $71.14 - $110.75

Q3 2015

Shares 121,316 Value ($000) $9,747 Avg Close $111.10 Range $76.46 - $137.89

Q2 2015

Shares 127,245 Value ($000) $15,247 Avg Close $119.50 Range $98.63 - $140.00

Q1 2015

Shares 125,203 Value ($000) $13,076 Avg Close $101.34 Range $82.06 - $121.93

Q4 2014

Shares 123,364 Value ($000) $11,967 Avg Close $92.65 Range $72.80 - $111.49

Q3 2014

Shares 123,392 Value ($000) $9,638 Avg Close $64.51 Range $51.93 - $79.88

Q2 2014

Shares 130,983 Value ($000) $8,273 Avg Close $59.44 Range $47.03 - $71.40

Q1 2014

Shares 222,322 Value ($000) $14,925 Avg Close $77.42 Range $60.24 - $112.57

Q4 2013

Shares 221,451 Value ($000) $14,246 Avg Close $59.65 Range $48.16 - $67.97

Q3 2013

Shares 227,153 Value ($000) $14,539 Avg Close $49.85 Range $31.75 - $65.83

Q2 2013

Shares 177,674 Value ($000) $5,510 Avg Close $26.61 Range $21.60 - $31.79

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	301,865	$120,033	$442.56	$387.03 - $495.55
Q3 2025	241,934	$110,284	$407.20	$309.57 - $484.21
Q2 2025	305,563	$99,633	$276.71	$205.87 - $327.21
Q1 2025	309,819	$83,645	$257.00	$230.79 - $300.90
Q4 2024	333,661	$78,520	$262.99	$229.86 - $304.39
Q3 2024	301,389	$82,885	$260.36	$231.01 - $287.55
Q2 2024	266,206	$64,702	$157.87	$141.98 - $252.87
Q1 2024	255,179	$38,137	$166.82	$143.52 - $199.38
Q4 2023	267,034	$51,126	$170.34	$148.10 - $198.00
Q3 2023	251,911	$44,611	$191.12	$168.65 - $218.88
Q2 2023	240,990	$45,775	$198.26	$183.00 - $212.47
Q1 2023	218,479	$43,762	$210.20	$179.19 - $242.39
Q4 2022	194,576	$46	$213.29	$181.65 - $242.97
Q3 2022	176,266	$35,290	$190.74	$135.46 - $236.80
Q2 2022	173,425	$25,292	$141.87	$117.58 - $180.35
Q1 2022	181,271	$29,601	$152.35	$125.00 - $174.66
Q4 2021	179,160	$30,383	$185.86	$154.82 - $212.00
Q3 2021	187,263	$35,351	$187.58	$166.16 - $209.73
Q2 2021	204,999	$34,747	$146.46	$125.08 - $177.53
Q1 2021	227,702	$32,152	$150.49	$124.00 - $178.41
Q4 2020	235,001	$30,545	$133.53	$119.29 - $148.76
Q3 2020	238,021	$34,654	$142.10	$119.67 - $167.33
Q2 2020	246,330	$36,483	$134.81	$98.01 - $158.37
Q1 2020	265,758	$28,926	$115.43	$84.97 - $134.51
Q4 2019	261,245	$30,087	$99.70	$73.32 - $125.72
Q3 2019	258,967	$20,828	$79.11	$69.11 - $88.00
Q2 2019	251,258	$18,229	$76.72	$65.81 - $96.08
Q1 2019	224,470	$20,972	$83.64	$70.29 - $93.95
Q4 2018	225,148	$16,412	$76.92	$60.27 - $90.00
Q3 2018	158,895	$13,910	$100.59	$86.95 - $124.22
Q2 2018	161,942	$15,948	$99.19	$87.35 - $118.71
Q1 2018	167,072	$19,898	$128.92	$108.13 - $153.99
Q4 2017	173,757	$22,081	$125.65	$111.25 - $147.63
Q3 2017	180,058	$21,156	$85.36	$70.76 - $119.02
Q2 2017	179,429	$14,311	$63.91	$46.90 - $86.92
Q1 2017	112,778	$5,780	$46.22	$35.98 - $60.41
Q4 2016	111,350	$4,170	$41.87	$31.38 - $71.67
Q3 2016	110,655	$7,503	$70.55	$53.56 - $80.11
Q2 2016	101,569	$5,636	$63.00	$49.96 - $75.08
Q1 2016	102,430	$6,426	$66.49	$51.51 - $98.00
Q4 2015	99,578	$9,375	$92.72	$71.14 - $110.75
Q3 2015	121,316	$9,747	$111.10	$76.46 - $137.89
Q2 2015	127,245	$15,247	$119.50	$98.63 - $140.00
Q1 2015	125,203	$13,076	$101.34	$82.06 - $121.93
Q4 2014	123,364	$11,967	$92.65	$72.80 - $111.49
Q3 2014	123,392	$9,638	$64.51	$51.93 - $79.88
Q2 2014	130,983	$8,273	$59.44	$47.03 - $71.40
Q1 2014	222,322	$14,925	$77.42	$60.24 - $112.57
Q4 2013	221,451	$14,246	$59.65	$48.16 - $67.97
Q3 2013	227,153	$14,539	$49.85	$31.75 - $65.83
Q2 2013	177,674	$5,510	$26.61	$21.60 - $31.79