ALNYLAM PHARMACEUTICALS INC

Ticker: ALNY CUSIP: 02043Q107 Class: EQTY

NEW YORK STATE COMMON RETIREMENT FUND's Holding History (CIK: 0000810265)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 64,424 Value ($000) $25,618 Avg Close $442.56 Range $387.03 - $495.55

Q3 2025

Shares 64,424 Value ($000) $29,377 Avg Close $407.20 Range $309.57 - $484.21

Q2 2025

Shares 63,272 Value ($000) $20,632 Avg Close $276.71 Range $205.87 - $327.21

Q1 2025

Shares 64,272 Value ($000) $17,355 Avg Close $257.00 Range $230.79 - $300.90

Q4 2024

Shares 72,228 Value ($000) $16,996 Avg Close $262.99 Range $229.86 - $304.39

Q3 2024

Shares 76,228 Value ($000) $20,965 Avg Close $260.36 Range $231.01 - $287.55

Q2 2024

Shares 94,685 Value ($000) $23,008 Avg Close $157.87 Range $141.98 - $252.87

Q1 2024

Shares 93,766 Value ($000) $14,013 Avg Close $166.82 Range $143.52 - $199.38

Q4 2023

Shares 111,914 Value ($000) $21,421 Avg Close $170.34 Range $148.10 - $198.00

Q3 2023

Shares 124,963 Value ($000) $22,131 Avg Close $191.12 Range $168.65 - $218.88

Q2 2023

Shares 142,119 Value ($000) $26,994 Avg Close $198.26 Range $183.00 - $212.47

Q1 2023

Shares 148,088 Value ($000) $29,665 Avg Close $210.20 Range $179.19 - $242.39

Q4 2022

Shares 154,698 Value ($000) $36,764 Avg Close $213.29 Range $181.65 - $242.97

Q3 2022

Shares 148,018 Value ($000) $29,627 Avg Close $190.74 Range $135.46 - $236.80

Q2 2022

Shares 153,124 Value ($000) $22,333 Avg Close $141.87 Range $117.58 - $180.35

Q1 2022

Shares 186,700 Value ($000) $30,486 Avg Close $152.35 Range $125.00 - $174.66

Q4 2021

Shares 187,641 Value ($000) $31,820 Avg Close $185.86 Range $154.82 - $212.00

Q3 2021

Shares 180,924 Value ($000) $34,160 Avg Close $187.58 Range $166.16 - $209.73

Q2 2021

Shares 184,120 Value ($000) $31,212 Avg Close $146.46 Range $125.08 - $177.53

Q1 2021

Shares 184,454 Value ($000) $26,043 Avg Close $150.49 Range $124.00 - $178.41

Q4 2020

Shares 198,554 Value ($000) $25,806 Avg Close $133.53 Range $119.29 - $148.76

Q3 2020

Shares 219,754 Value ($000) $31,996 Avg Close $142.10 Range $119.67 - $167.33

Q2 2020

Shares 242,549 Value ($000) $35,924 Avg Close $134.81 Range $98.01 - $158.37

Q1 2020

Shares 240,229 Value ($000) $26,149 Avg Close $115.43 Range $84.97 - $134.51

Q4 2019

Shares 253,320 Value ($000) $29,175 Avg Close $99.70 Range $73.32 - $125.72

Q3 2019

Shares 260,833 Value ($000) $20,976 Avg Close $79.11 Range $69.11 - $88.00

Q2 2019

Shares 241,762 Value ($000) $17,542 Avg Close $76.72 Range $65.81 - $96.08

Q1 2019

Shares 223,363 Value ($000) $20,873 Avg Close $83.64 Range $70.29 - $93.95

Q4 2018

Shares 212,161 Value ($000) $15,469 Avg Close $76.92 Range $60.27 - $90.00

Q3 2018

Shares 206,808 Value ($000) $18,100 Avg Close $100.59 Range $86.95 - $124.22

Q2 2018

Shares 202,981 Value ($000) $19,992 Avg Close $99.19 Range $87.35 - $118.71

Q1 2018

Shares 215,481 Value ($000) $25,664 Avg Close $128.92 Range $108.13 - $153.99

Q4 2017

Shares 217,081 Value ($000) $27,580 Avg Close $125.65 Range $111.25 - $147.63

Q3 2017

Shares 216,488 Value ($000) $25,435 Avg Close $85.36 Range $70.76 - $119.02

Q2 2017

Shares 202,988 Value ($000) $16,190 Avg Close $63.91 Range $46.90 - $86.92

Q1 2017

Shares 213,251 Value ($000) $10,929 Avg Close $46.22 Range $35.98 - $60.41

Q4 2016

Shares 179,854 Value ($000) $6,734 Avg Close $41.87 Range $31.38 - $71.67

Q3 2016

Shares 215,277 Value ($000) $14,591 Avg Close $70.55 Range $53.56 - $80.11

Q2 2016

Shares 229,977 Value ($000) $12,761 Avg Close $63.00 Range $49.96 - $75.08

Q1 2016

Shares 221,577 Value ($000) $13,908 Avg Close $66.49 Range $51.51 - $98.00

Q4 2015

Shares 224,877 Value ($000) $21,170 Avg Close $92.72 Range $71.14 - $110.75

Q3 2015

Shares 205,723 Value ($000) $16,532 Avg Close $111.10 Range $76.46 - $137.89

Q2 2015

Shares 135,522 Value ($000) $16,245 Avg Close $119.50 Range $98.63 - $140.00

Q1 2015

Shares 36,794 Value ($000) $3,842 Avg Close $101.34 Range $82.06 - $121.93

Q4 2014

Shares 41,123 Value ($000) $3,989 Avg Close $92.65 Range $72.80 - $111.49

Q3 2014

Shares 131,254 Value ($000) $10,251 Avg Close $64.51 Range $51.93 - $79.88

Q2 2014

Shares 134,989 Value ($000) $8,527 Avg Close $59.44 Range $47.03 - $71.40

Q1 2014

Shares 121,640 Value ($000) $8,167 Avg Close $77.42 Range $60.24 - $112.57

Q4 2013

Shares 85,017 Value ($000) $5,469 Avg Close $59.65 Range $48.16 - $67.97

Q3 2013

Shares 72,500 Value ($000) $4,641 Avg Close $49.85 Range $31.75 - $65.83

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	64,424	$25,618	$442.56	$387.03 - $495.55
Q3 2025	64,424	$29,377	$407.20	$309.57 - $484.21
Q2 2025	63,272	$20,632	$276.71	$205.87 - $327.21
Q1 2025	64,272	$17,355	$257.00	$230.79 - $300.90
Q4 2024	72,228	$16,996	$262.99	$229.86 - $304.39
Q3 2024	76,228	$20,965	$260.36	$231.01 - $287.55
Q2 2024	94,685	$23,008	$157.87	$141.98 - $252.87
Q1 2024	93,766	$14,013	$166.82	$143.52 - $199.38
Q4 2023	111,914	$21,421	$170.34	$148.10 - $198.00
Q3 2023	124,963	$22,131	$191.12	$168.65 - $218.88
Q2 2023	142,119	$26,994	$198.26	$183.00 - $212.47
Q1 2023	148,088	$29,665	$210.20	$179.19 - $242.39
Q4 2022	154,698	$36,764	$213.29	$181.65 - $242.97
Q3 2022	148,018	$29,627	$190.74	$135.46 - $236.80
Q2 2022	153,124	$22,333	$141.87	$117.58 - $180.35
Q1 2022	186,700	$30,486	$152.35	$125.00 - $174.66
Q4 2021	187,641	$31,820	$185.86	$154.82 - $212.00
Q3 2021	180,924	$34,160	$187.58	$166.16 - $209.73
Q2 2021	184,120	$31,212	$146.46	$125.08 - $177.53
Q1 2021	184,454	$26,043	$150.49	$124.00 - $178.41
Q4 2020	198,554	$25,806	$133.53	$119.29 - $148.76
Q3 2020	219,754	$31,996	$142.10	$119.67 - $167.33
Q2 2020	242,549	$35,924	$134.81	$98.01 - $158.37
Q1 2020	240,229	$26,149	$115.43	$84.97 - $134.51
Q4 2019	253,320	$29,175	$99.70	$73.32 - $125.72
Q3 2019	260,833	$20,976	$79.11	$69.11 - $88.00
Q2 2019	241,762	$17,542	$76.72	$65.81 - $96.08
Q1 2019	223,363	$20,873	$83.64	$70.29 - $93.95
Q4 2018	212,161	$15,469	$76.92	$60.27 - $90.00
Q3 2018	206,808	$18,100	$100.59	$86.95 - $124.22
Q2 2018	202,981	$19,992	$99.19	$87.35 - $118.71
Q1 2018	215,481	$25,664	$128.92	$108.13 - $153.99
Q4 2017	217,081	$27,580	$125.65	$111.25 - $147.63
Q3 2017	216,488	$25,435	$85.36	$70.76 - $119.02
Q2 2017	202,988	$16,190	$63.91	$46.90 - $86.92
Q1 2017	213,251	$10,929	$46.22	$35.98 - $60.41
Q4 2016	179,854	$6,734	$41.87	$31.38 - $71.67
Q3 2016	215,277	$14,591	$70.55	$53.56 - $80.11
Q2 2016	229,977	$12,761	$63.00	$49.96 - $75.08
Q1 2016	221,577	$13,908	$66.49	$51.51 - $98.00
Q4 2015	224,877	$21,170	$92.72	$71.14 - $110.75
Q3 2015	205,723	$16,532	$111.10	$76.46 - $137.89
Q2 2015	135,522	$16,245	$119.50	$98.63 - $140.00
Q1 2015	36,794	$3,842	$101.34	$82.06 - $121.93
Q4 2014	41,123	$3,989	$92.65	$72.80 - $111.49
Q3 2014	131,254	$10,251	$64.51	$51.93 - $79.88
Q2 2014	134,989	$8,527	$59.44	$47.03 - $71.40
Q1 2014	121,640	$8,167	$77.42	$60.24 - $112.57
Q4 2013	85,017	$5,469	$59.65	$48.16 - $67.97
Q3 2013	72,500	$4,641	$49.85	$31.75 - $65.83