ALNYLAM PHARMACEUTICALS INC

Ticker: ALNY CUSIP: 02043Q107 Class: EQTY

ROYAL LONDON ASSET MANAGEMENT LTD's Holding History (CIK: 0000863748)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 253,072 Value ($000) $100,634 Avg Close $442.56 Range $387.03 - $495.55

Q3 2025

Shares 257,313 Value ($000) $117,335 Avg Close $407.20 Range $309.57 - $484.21

Q2 2025

Shares 259,071 Value ($000) $84,480 Avg Close $276.71 Range $205.87 - $327.21

Q1 2025

Shares 286,943 Value ($000) $77,480 Avg Close $257.00 Range $230.79 - $300.90

Q4 2024

Shares 281,509 Value ($000) $66,242 Avg Close $262.99 Range $229.86 - $304.39

Q3 2024

Shares 279,750 Value ($000) $76,940 Avg Close $260.36 Range $231.01 - $287.55

Q2 2024

Shares 282,345 Value ($000) $68,610 Avg Close $157.87 Range $141.98 - $252.87

Q1 2024

Shares 326,869 Value ($000) $48,851 Avg Close $166.82 Range $143.52 - $199.38

Q4 2023

Shares 308,824 Value ($000) $59,112 Avg Close $170.34 Range $148.10 - $198.00

Q3 2023

Shares 306,595 Value ($000) $54,303 Avg Close $191.12 Range $168.65 - $218.88

Q2 2023

Shares 164,238 Value ($000) $31,209 Avg Close $198.26 Range $183.00 - $212.47

Q1 2023

Shares 124,771 Value ($000) $24,994 Avg Close $210.20 Range $179.19 - $242.39

Q4 2022

Shares 42,078 Value ($000) $9,994 Avg Close $213.29 Range $181.65 - $242.97

Q3 2022

Shares 40,642 Value ($000) $8,130 Avg Close $190.74 Range $135.46 - $236.80

Q2 2022

Shares 42,411 Value ($000) $6,188 Avg Close $141.87 Range $117.58 - $180.35

Q1 2022

Shares 41,560 Value ($000) $6,788 Avg Close $152.35 Range $125.00 - $174.66

Q4 2021

Shares 40,303 Value ($000) $6,842 Avg Close $185.86 Range $154.82 - $212.00

Q3 2021

Shares 41,280 Value ($000) $7,799 Avg Close $187.58 Range $166.16 - $209.73

Q2 2021

Shares 42,392 Value ($000) $7,184 Avg Close $146.46 Range $125.08 - $177.53

Q1 2021

Shares 42,392 Value ($000) $5,987 Avg Close $150.49 Range $124.00 - $178.41

Q4 2020

Shares 41,636 Value ($000) $5,415 Avg Close $133.53 Range $119.29 - $148.76

Q3 2020

Shares 42,683 Value ($000) $6,189 Avg Close $142.10 Range $119.67 - $167.33

Q2 2020

Shares 40,708 Value ($000) $6,026 Avg Close $134.81 Range $98.01 - $158.37

Q1 2020

Shares 40,708 Value ($000) $4,430 Avg Close $115.43 Range $84.97 - $134.51

Q4 2019

Shares 40,708 Value ($000) $4,667 Avg Close $99.70 Range $73.32 - $125.72

Q3 2019

Shares 39,957 Value ($000) $3,212 Avg Close $79.11 Range $69.11 - $88.00

Q2 2019

Shares 37,038 Value ($000) $2,689 Avg Close $76.72 Range $65.81 - $96.08

Q1 2019

Shares 36,294 Value ($000) $3,393 Avg Close $83.64 Range $70.29 - $93.95

Q4 2018

Shares 66,803 Value ($000) $4,703 Avg Close $76.92 Range $60.27 - $90.00

Q3 2018

Shares 57,237 Value ($000) $5,010 Avg Close $100.59 Range $86.95 - $124.22

Q2 2018

Shares 57,152 Value ($000) $5,629 Avg Close $99.19 Range $87.35 - $118.71

Q2 2016

Shares 70,380 Value ($000) $3,905 Avg Close $63.00 Range $49.96 - $75.08

Q1 2016

Shares 1,127,456 Value ($000) $18 Avg Close $66.49 Range $51.51 - $98.00

Q4 2015

Shares 70,047 Value ($000) $6,622 Avg Close $92.72 Range $71.14 - $110.75

Q3 2015

Shares 68,258 Value ($000) $5,485 Avg Close $111.10 Range $76.46 - $137.89

Q4 2014

Shares 27,500 Value ($000) $26,676 Avg Close $92.65 Range $72.80 - $111.49

Q3 2014

Shares 28,800 Value ($000) $2,264 Avg Close $64.51 Range $51.93 - $79.88

Q2 2014

Shares 28,800 Value ($000) $1,650 Avg Close $59.44 Range $47.03 - $71.40

Q1 2014

Shares 25,400 Value ($000) $1,461 Avg Close $77.42 Range $60.24 - $112.57

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	253,072	$100,634	$442.56	$387.03 - $495.55
Q3 2025	257,313	$117,335	$407.20	$309.57 - $484.21
Q2 2025	259,071	$84,480	$276.71	$205.87 - $327.21
Q1 2025	286,943	$77,480	$257.00	$230.79 - $300.90
Q4 2024	281,509	$66,242	$262.99	$229.86 - $304.39
Q3 2024	279,750	$76,940	$260.36	$231.01 - $287.55
Q2 2024	282,345	$68,610	$157.87	$141.98 - $252.87
Q1 2024	326,869	$48,851	$166.82	$143.52 - $199.38
Q4 2023	308,824	$59,112	$170.34	$148.10 - $198.00
Q3 2023	306,595	$54,303	$191.12	$168.65 - $218.88
Q2 2023	164,238	$31,209	$198.26	$183.00 - $212.47
Q1 2023	124,771	$24,994	$210.20	$179.19 - $242.39
Q4 2022	42,078	$9,994	$213.29	$181.65 - $242.97
Q3 2022	40,642	$8,130	$190.74	$135.46 - $236.80
Q2 2022	42,411	$6,188	$141.87	$117.58 - $180.35
Q1 2022	41,560	$6,788	$152.35	$125.00 - $174.66
Q4 2021	40,303	$6,842	$185.86	$154.82 - $212.00
Q3 2021	41,280	$7,799	$187.58	$166.16 - $209.73
Q2 2021	42,392	$7,184	$146.46	$125.08 - $177.53
Q1 2021	42,392	$5,987	$150.49	$124.00 - $178.41
Q4 2020	41,636	$5,415	$133.53	$119.29 - $148.76
Q3 2020	42,683	$6,189	$142.10	$119.67 - $167.33
Q2 2020	40,708	$6,026	$134.81	$98.01 - $158.37
Q1 2020	40,708	$4,430	$115.43	$84.97 - $134.51
Q4 2019	40,708	$4,667	$99.70	$73.32 - $125.72
Q3 2019	39,957	$3,212	$79.11	$69.11 - $88.00
Q2 2019	37,038	$2,689	$76.72	$65.81 - $96.08
Q1 2019	36,294	$3,393	$83.64	$70.29 - $93.95
Q4 2018	66,803	$4,703	$76.92	$60.27 - $90.00
Q3 2018	57,237	$5,010	$100.59	$86.95 - $124.22
Q2 2018	57,152	$5,629	$99.19	$87.35 - $118.71
Q2 2016	70,380	$3,905	$63.00	$49.96 - $75.08
Q1 2016	1,127,456	$18	$66.49	$51.51 - $98.00
Q4 2015	70,047	$6,622	$92.72	$71.14 - $110.75
Q3 2015	68,258	$5,485	$111.10	$76.46 - $137.89
Q4 2014	27,500	$26,676	$92.65	$72.80 - $111.49
Q3 2014	28,800	$2,264	$64.51	$51.93 - $79.88
Q2 2014	28,800	$1,650	$59.44	$47.03 - $71.40
Q1 2014	25,400	$1,461	$77.42	$60.24 - $112.57