ALNYLAM PHARMACEUTICALS INC

Ticker: ALNY CUSIP: 02043Q107 Class: EQTY

GILDER GAGNON HOWE & CO LLC's Holding History (CIK: 0000902464)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 319,305 Value ($000) $126,972 Avg Close $442.56 Range $387.03 - $495.55

Q3 2025

Shares 329,321 Value ($000) $150,171 Avg Close $407.20 Range $309.57 - $484.21

Q2 2025

Shares 337,088 Value ($000) $109,921 Avg Close $276.71 Range $205.87 - $327.21

Q1 2025

Shares 345,575 Value ($000) $93,312 Avg Close $257.00 Range $230.79 - $300.90

Q4 2024

Shares 365,463 Value ($000) $85,997 Avg Close $262.99 Range $229.86 - $304.39

Q3 2024

Shares 383,993 Value ($000) $105,610 Avg Close $260.36 Range $231.01 - $287.55

Q2 2024

Shares 398,616 Value ($000) $96,864 Avg Close $157.87 Range $141.98 - $252.87

Q1 2024

Shares 405,173 Value ($000) $60,553 Avg Close $166.82 Range $143.52 - $199.38

Q4 2023

Shares 587,045 Value ($000) $112,366 Avg Close $170.34 Range $148.10 - $198.00

Q3 2023

Shares 594,979 Value ($000) $105,371 Avg Close $191.12 Range $168.65 - $218.88

Q2 2023

Shares 598,696 Value ($000) $113,716 Avg Close $198.26 Range $183.00 - $212.47

Q1 2023

Shares 621,208 Value ($000) $124,440 Avg Close $210.20 Range $179.19 - $242.39

Q4 2022

Shares 649,617 Value ($000) $154,381 Avg Close $213.29 Range $181.65 - $242.97

Q3 2022

Shares 663,983 Value ($000) $132,903 Avg Close $190.74 Range $135.46 - $236.80

Q2 2022

Shares 754,575 Value ($000) $110,055 Avg Close $141.87 Range $117.58 - $180.35

Q1 2022

Shares 791,224 Value ($000) $129,199 Avg Close $152.35 Range $125.00 - $174.66

Q4 2021

Shares 839,568 Value ($000) $142,374 Avg Close $185.86 Range $154.82 - $212.00

Q3 2021

Shares 923,684 Value ($000) $174,401 Avg Close $187.58 Range $166.16 - $209.73

Q2 2021

Shares 925,726 Value ($000) $156,929 Avg Close $146.46 Range $125.08 - $177.53

Q1 2021

Shares 929,643 Value ($000) $131,256 Avg Close $150.49 Range $124.00 - $178.41

Q4 2020

Shares 884,130 Value ($000) $114,910 Avg Close $133.53 Range $119.29 - $148.76

Q3 2020

Shares 890,416 Value ($000) $129,645 Avg Close $142.10 Range $119.67 - $167.33

Q2 2020

Shares 883,768 Value ($000) $130,895 Avg Close $134.81 Range $98.01 - $158.37

Q1 2020

Shares 919,177 Value ($000) $100,052 Avg Close $115.43 Range $84.97 - $134.51

Q4 2019

Shares 936,479 Value ($000) $107,854 Avg Close $99.70 Range $73.32 - $125.72

Q3 2019

Shares 954,105 Value ($000) $76,729 Avg Close $79.11 Range $69.11 - $88.00

Q2 2019

Shares 977,819 Value ($000) $70,951 Avg Close $76.72 Range $65.81 - $96.08

Q1 2019

Shares 987,770 Value ($000) $92,307 Avg Close $83.64 Range $70.29 - $93.95

Q4 2018

Shares 954,596 Value ($000) $69,600 Avg Close $76.92 Range $60.27 - $90.00

Q3 2018

Shares 1,088,895 Value ($000) $95,300 Avg Close $100.59 Range $86.95 - $124.22

Q2 2018

Shares 1,094,716 Value ($000) $107,819 Avg Close $99.19 Range $87.35 - $118.71

Q1 2018

Shares 1,210,422 Value ($000) $144,161 Avg Close $128.92 Range $108.13 - $153.99

Q4 2017

Shares 1,217,367 Value ($000) $154,666 Avg Close $125.65 Range $111.25 - $147.63

Q3 2017

Shares 1,120,555 Value ($000) $131,654 Avg Close $85.36 Range $70.76 - $119.02

Q2 2017

Shares 1,185,380 Value ($000) $94,546 Avg Close $63.91 Range $46.90 - $86.92

Q1 2017

Shares 1,206,049 Value ($000) $61,810 Avg Close $46.22 Range $35.98 - $60.41

Q4 2016

Shares 1,230,794 Value ($000) $46,081 Avg Close $41.87 Range $31.38 - $71.67

Q3 2016

Shares 1,361,656 Value ($000) $92,293 Avg Close $70.55 Range $53.56 - $80.11

Q2 2016

Shares 1,393,947 Value ($000) $77,350 Avg Close $63.00 Range $49.96 - $75.08

Q1 2016

Shares 1,414,631 Value ($000) $88,796 Avg Close $66.49 Range $51.51 - $98.00

Q4 2015

Shares 1,477,367 Value ($000) $139,079 Avg Close $92.72 Range $71.14 - $110.75

Q3 2015

Shares 1,493,847 Value ($000) $120,046 Avg Close $111.10 Range $76.46 - $137.89

Q2 2015

Shares 1,506,238 Value ($000) $180,553 Avg Close $119.50 Range $98.63 - $140.00

Q1 2015

Shares 1,748,367 Value ($000) $182,564 Avg Close $101.34 Range $82.06 - $121.93

Q4 2014

Shares 1,950,269 Value ($000) $189,176 Avg Close $92.65 Range $72.80 - $111.49

Q3 2014

Shares 1,987,562 Value ($000) $155,229 Avg Close $64.51 Range $51.93 - $79.88

Q2 2014

Shares 1,995,870 Value ($000) $126,079 Avg Close $59.44 Range $47.03 - $71.40

Q1 2014

Shares 1,915,598 Value ($000) $128,613 Avg Close $77.42 Range $60.24 - $112.57

Q4 2013

Shares 1,899,152 Value ($000) $122,115 Avg Close $59.65 Range $48.16 - $67.97

Q3 2013

Shares 1,921,078 Value ($000) $122,968 Avg Close $49.85 Range $31.75 - $65.83

Q2 2013

Shares 1,676,428 Value ($000) $51,969,268 Avg Close $26.61 Range $21.60 - $31.79

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	319,305	$126,972	$442.56	$387.03 - $495.55
Q3 2025	329,321	$150,171	$407.20	$309.57 - $484.21
Q2 2025	337,088	$109,921	$276.71	$205.87 - $327.21
Q1 2025	345,575	$93,312	$257.00	$230.79 - $300.90
Q4 2024	365,463	$85,997	$262.99	$229.86 - $304.39
Q3 2024	383,993	$105,610	$260.36	$231.01 - $287.55
Q2 2024	398,616	$96,864	$157.87	$141.98 - $252.87
Q1 2024	405,173	$60,553	$166.82	$143.52 - $199.38
Q4 2023	587,045	$112,366	$170.34	$148.10 - $198.00
Q3 2023	594,979	$105,371	$191.12	$168.65 - $218.88
Q2 2023	598,696	$113,716	$198.26	$183.00 - $212.47
Q1 2023	621,208	$124,440	$210.20	$179.19 - $242.39
Q4 2022	649,617	$154,381	$213.29	$181.65 - $242.97
Q3 2022	663,983	$132,903	$190.74	$135.46 - $236.80
Q2 2022	754,575	$110,055	$141.87	$117.58 - $180.35
Q1 2022	791,224	$129,199	$152.35	$125.00 - $174.66
Q4 2021	839,568	$142,374	$185.86	$154.82 - $212.00
Q3 2021	923,684	$174,401	$187.58	$166.16 - $209.73
Q2 2021	925,726	$156,929	$146.46	$125.08 - $177.53
Q1 2021	929,643	$131,256	$150.49	$124.00 - $178.41
Q4 2020	884,130	$114,910	$133.53	$119.29 - $148.76
Q3 2020	890,416	$129,645	$142.10	$119.67 - $167.33
Q2 2020	883,768	$130,895	$134.81	$98.01 - $158.37
Q1 2020	919,177	$100,052	$115.43	$84.97 - $134.51
Q4 2019	936,479	$107,854	$99.70	$73.32 - $125.72
Q3 2019	954,105	$76,729	$79.11	$69.11 - $88.00
Q2 2019	977,819	$70,951	$76.72	$65.81 - $96.08
Q1 2019	987,770	$92,307	$83.64	$70.29 - $93.95
Q4 2018	954,596	$69,600	$76.92	$60.27 - $90.00
Q3 2018	1,088,895	$95,300	$100.59	$86.95 - $124.22
Q2 2018	1,094,716	$107,819	$99.19	$87.35 - $118.71
Q1 2018	1,210,422	$144,161	$128.92	$108.13 - $153.99
Q4 2017	1,217,367	$154,666	$125.65	$111.25 - $147.63
Q3 2017	1,120,555	$131,654	$85.36	$70.76 - $119.02
Q2 2017	1,185,380	$94,546	$63.91	$46.90 - $86.92
Q1 2017	1,206,049	$61,810	$46.22	$35.98 - $60.41
Q4 2016	1,230,794	$46,081	$41.87	$31.38 - $71.67
Q3 2016	1,361,656	$92,293	$70.55	$53.56 - $80.11
Q2 2016	1,393,947	$77,350	$63.00	$49.96 - $75.08
Q1 2016	1,414,631	$88,796	$66.49	$51.51 - $98.00
Q4 2015	1,477,367	$139,079	$92.72	$71.14 - $110.75
Q3 2015	1,493,847	$120,046	$111.10	$76.46 - $137.89
Q2 2015	1,506,238	$180,553	$119.50	$98.63 - $140.00
Q1 2015	1,748,367	$182,564	$101.34	$82.06 - $121.93
Q4 2014	1,950,269	$189,176	$92.65	$72.80 - $111.49
Q3 2014	1,987,562	$155,229	$64.51	$51.93 - $79.88
Q2 2014	1,995,870	$126,079	$59.44	$47.03 - $71.40
Q1 2014	1,915,598	$128,613	$77.42	$60.24 - $112.57
Q4 2013	1,899,152	$122,115	$59.65	$48.16 - $67.97
Q3 2013	1,921,078	$122,968	$49.85	$31.75 - $65.83
Q2 2013	1,676,428	$51,969,268	$26.61	$21.60 - $31.79